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Investigating the Relationship Between Shift Work Schedule and Blood and Metabolic Parameters: A 10-Years Retrospective Cohort Study Publisher Pubmed



Soltanzadeh A1 ; Eyvazlou M2 ; Mohammadghasemi M3 ; Sadeghiyarandi M4 ; Rahimkhani M5 ; Ghasemi N6 ; Bonyadi M7 ; Sadeghiyarandi M4
Authors
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Authors Affiliations
  1. 1. Department of Occupational Health, School of Public Health, Qom University of Medical Sciences, Qom, Iran
  2. 2. Department of Occupational Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Environmental Science and Engineering, West Tehran Branch, Islamic Azad University, Tehran, Iran
  4. 4. Department of Counseling, Faculty of Humanities, Science and Research Branch, Islamic Azad University, Tehran, Iran
  5. 5. Lab Medical Sciences Department, Allied Medical Sciences Faculty, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Ergonomics, Faculty of Health, Yazd University of Medical Sciences, Yazd, Iran
  7. 7. Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran

Source: Scientific Reports Published:2024


Abstract

Shift work has become increasingly common in modern society. Shift work has been associated with a range of negative health outcomes. Therefore, this 10-years retrospective cohort study, aimed to investigate the relationship between shift work and blood and metabolic parameters. This retrospective cohort study was conducted in a metal parts manufacturing industry in 2023. In this study, 204 shift workers and 204 day workers were examined. All the studied blood and metabolic parameters were collected by reviewing the medical records of all participants during a 10-years period (2013–2022). Moreover, the amounts of physical, chemical, and ergonomics harmful agents in the work environment were investigated. All the collected data were analyzed using SPSS version 25.0. The values of Body Mass Index (BMI), Red Blood Cell Count (RBC), Platelets Count (PLT), Thyroid-Stimulating Hormone Level (TSH), Fasting Blood Sugar Level (FBS), Creatinine, Triglyceride (TG), Liver Enzymes level (SGOT and SGPT), and Systolic Blood Pressure (SBP) were higher among the shift work employees, and a significant difference was observed between the values of these parameters between the two groups. The results of logistic regression showed that the highest effect of shift work was observed on the parameters of FBS, TG, SGPT, TSH, Physical activity, BMI, Sleep duration, PLT, and Sleep quality with beta coefficient values of 0.49, 0.33, 0.29, 0.29, 0.20, 0.18, 0.14, 0.13 and, 0.11, respectively (p-value < 0.01). The present study contributes to a growing body of evidence that blood and metabolic factors are likely to be influenced by shift work. These findings have important implications for policy makers, highlighting the need for interventions to mitigate the negative health effects of shift work on workers. © The Author(s) 2024.
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