Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.]

Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.] Publisher

Shagholian M¹ ; Goli SAH¹ ; Shirvani A¹ ; Aghaghazvini MR² ; Asgary S³

Show Affiliations

1. Department of Food Science and Technology, College of Agriculture, Isfahan University of Technology, Isfahan, 84156 83111, Iran
2. Isfahan Center of Health Research, National Institute of Health Research, Tehran University of Medical Sciences, Tehran, Iran
3. Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of medical Sciences, Isfahan, Iran

Source: Grasas y Aceites Published:2019

Abstract

Conjugated linoleic acid (CLA) and conjugated linolenic acid (CLnA) have been known to have several health-promoting effects. The aim of this study was to introduce a novel structured lipid (SL) including both CLA and CLnA (cis9, trans11, cis13-18:3, punicic acid) into one triacylglycerol (TAG) molecule through enzymatic interesterification and investigate its effect on body weight, liver and serum lipids in Wistar rats. CLA oil, pomegranate seed oil (as a rich source of CLnA) and soybean oil (as a negative control) were applied as other experimental oils. The rats were fed the oils at 1500 mg/kg body weight per day via oral gavage for 45 days. Gas chromatography analysis showed that SL included CLnA and CLA in roughly equal concentrations. The in vivo study revealed that SL had the greatest effect on the reduction in liver lipid weight (4.65 g/100g of liver) and liver TAG (13.28 mg/g) compared to soybean oil (8.7 g/100g and 18.8 mg/g, respectively). High density lipoprotein cholesterol (HDL-C) in the serum of rats which were fed CLA oil significantly (p < 0.05) increased (from 0.95 to 1.14 mmol/l). Pomegranate seed oil reduced low density lipoprotein cholesterol (LDL-C) and total cholesterol (about 40% and 24% reduction, respectively). A remarkable TAG reduction (p < 0.05) was observed in all treated rats. ©2019 CSIC.

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Style	Citing Format
MLA	Shagholian M, et al.. "Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.]." Grasas y Aceites, vol. 70, no. 2, 2019, pp. -.
APA	Shagholian M, Goli SAH, Shirvani A, Aghaghazvini MR, Asgary S (2019). Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.]. Grasas y Aceites, 70(2), -.
Chicago	Shagholian M, Goli SAH, Shirvani A, Aghaghazvini MR, Asgary S. "Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.]." Grasas y Aceites 70, no. 2 (2019): -.
Harvard	Shagholian M et al. (2019) 'Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.]', Grasas y Aceites, 70(2), pp. -.
Vancouver	Shagholian M, Goli SAH, Shirvani A, Aghaghazvini MR, Asgary S. Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.]. Grasas y Aceites. 2019;70(2):-.
BibTex	@article{ author = {Shagholian M and Goli SAH and Shirvani A and Aghaghazvini MR and Asgary S}, title = {Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.]}, journal = {Grasas y Aceites}, volume = {70}, number = {2}, pages = {-}, year = {2019} }
RIS	TY - JOUR AU - Shagholian M AU - Goli SAH AU - Shirvani A AU - Aghaghazvini MR AU - Asgary S TI - Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.] JO - Grasas y Aceites VL - 70 IS - 2 SP - EP - PY - 2019 ER -

Style

Citing Format

MLA

Shagholian M, et al.. "Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.]." Grasas y Aceites, vol. 70, no. 2, 2019, pp. -.

APA

Shagholian M, Goli SAH, Shirvani A, Aghaghazvini MR, Asgary S (2019). Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.]. Grasas y Aceites, 70(2), -.

Chicago

Shagholian M, Goli SAH, Shirvani A, Aghaghazvini MR, Asgary S. "Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.]." Grasas y Aceites 70, no. 2 (2019): -.

Harvard

Shagholian M et al. (2019) 'Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.]', Grasas y Aceites, 70(2), pp. -.

Vancouver

Shagholian M, Goli SAH, Shirvani A, Aghaghazvini MR, Asgary S. Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.]. Grasas y Aceites. 2019;70(2):-.

BibTex

@article{ author = {Shagholian M and Goli SAH and Shirvani A and Aghaghazvini MR and Asgary S}, title = {Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.]}, journal = {Grasas y Aceites}, volume = {70}, number = {2}, pages = {-}, year = {2019} }

RIS

TY - JOUR
AU - Shagholian M
AU - Goli SAH
AU - Shirvani A
AU - Aghaghazvini MR
AU - Asgary S
TI - Liver and Serum Lipids in Wistar Rats Fed a Novel Structured Lipid Containing Conjugated Linoleic Acid and Conjugated Linolenic Acid; [Lipidos Hepaticos Y Sericos En Ratas Wistar Alimentadas Con Nuevos Lipidos Estructurados Que Con-Tienen Acido Linoleico Conjugado Y Acido Linolenico Conjugado.]
JO - Grasas y Aceites
VL - 70
IS - 2
SP -
EP -
PY - 2019
ER -

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