Mitochondrial Proteome Profiling of Leishmania Tropica

Mitochondrial Proteome Profiling of Leishmania Tropica Publisher Pubmed

Tasbihi M¹ ; Shekari F^{2, 3} ; Hajjaran H³ ; Masoori L¹ ; Hadighi R¹

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1. Department of Medical Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
2. Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
3. Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Source: Microbial Pathogenesis Published:2019

Abstract

The mitochondrion of kinetoplastida has unique characteristics both in structure and function. To better understand the mitochondrial proteome of the Leishmania tropica promastigote stage, liquid chromatography coupled with mass spectrometry (LC/MS/MS) approach was used. In the wake of mitochondria isolation and purity validation, 1212 proteins were identified, among which approximately 44% of proteins belonged to the mitochondrial proteome. Several functions were enriched in mitochondrial proteome including tricarboxylic acid cycle and respiratory chain, protein folding, signalling, transport, lipid metabolism, amino acid, and nucleotide metabolism. Furthermore, the result of the present research was compared with the previous related studies. Gaining more information about vital metabolism of the cell and molecules can be used for therapeutic purposes. © 2019 Elsevier Ltd

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Style	Citing Format
MLA	Tasbihi M, et al.. "Mitochondrial Proteome Profiling of Leishmania Tropica." Microbial Pathogenesis, vol. 133, no. , 2019, pp. -.
APA	Tasbihi M, Shekari F, Hajjaran H, Masoori L, Hadighi R (2019). Mitochondrial Proteome Profiling of Leishmania Tropica. Microbial Pathogenesis, 133(), -.
Chicago	Tasbihi M, Shekari F, Hajjaran H, Masoori L, Hadighi R. "Mitochondrial Proteome Profiling of Leishmania Tropica." Microbial Pathogenesis 133, no. (2019): -.
Harvard	Tasbihi M et al. (2019) 'Mitochondrial Proteome Profiling of Leishmania Tropica', Microbial Pathogenesis, 133(), pp. -.
Vancouver	Tasbihi M, Shekari F, Hajjaran H, Masoori L, Hadighi R. Mitochondrial Proteome Profiling of Leishmania Tropica. Microbial Pathogenesis. 2019;133():-.
BibTex	@article{ author = {Tasbihi M and Shekari F and Hajjaran H and Masoori L and Hadighi R}, title = {Mitochondrial Proteome Profiling of Leishmania Tropica}, journal = {Microbial Pathogenesis}, volume = {133}, number = {}, pages = {-}, year = {2019} }
RIS	TY - JOUR AU - Tasbihi M AU - Shekari F AU - Hajjaran H AU - Masoori L AU - Hadighi R TI - Mitochondrial Proteome Profiling of Leishmania Tropica JO - Microbial Pathogenesis VL - 133 IS - SP - EP - PY - 2019 ER -

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