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Botanicals: An Alternative Remedy to Radiotherapy-Induced Dysuria Publisher Pubmed



Jaladat AM1 ; Atarzadeh F1 ; Rezaeizadeh H2 ; Mofid B3 ; Mosalaie A4 ; Farhan F5 ; Amin G6
Authors
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Authors Affiliations
  1. 1. Department of Traditional Iranian Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Traditional Iranian Medicine and Traditional Medicine and Pharmacy Research Center, Faculty of Traditional Medicine, Tehran University of Medical Science, Tehran, Iran
  3. 3. Department of Radiation Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Department of Radiation Oncology, Shiraz University of Medical Sciences, Shiraz, Iran
  5. 5. Department of Radiation Oncology, Cancer Institute, Imam Khomeini Hospital, Tehran, Iran
  6. 6. Department of Traditional Iranian Medicine and Pharmacy Research Center, Faculty of traditional Medicine, Tehran University of Medical Science, Tehran, Iran

Source: Complementary Therapies in Medicine Published:2015


Abstract

Everyday, many patients get radiotherapy for prostatic, rectal, uterine cervix and other pelvic organs cancer. Dysuria is common in pelvic, especially prostate radiotherapy, but there is not any established and confirmed treatment for this therapeutic side effect. Therefore, an alternative therapeutic method, using herbal preparation, may be an effective solution. This study seeks a defensible suggestion in Iranian Traditional Medicine (ITM).In ITM, a few medicinal herbs such as Plantago psyllium, Cydonia oblonga, Portulaca oleracea and some species of Malvaceae and Cucurbitaceae family are indicated in treating dysuria secondary to urethral moisturizing layer defect and inflammatory disorders. Most of these herbs have mucilaginous characteristics and tissue regeneration ability. This choice can be an appropriate one for radiotherapy-induced dysuria as it is produced by a similar pathophysiology with bladder cell layer injury and urethritis. Pharmacological properties such as anti-oxidant, anti-inflammatory, and anti-ulcerogenic activity of the offered herbs make its use justifiable. In lack of sufficient clinical trials to clarify the clinical outcome, further clinical investigation seems to be necessary. © 2014 Elsevier Ltd.
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