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Pet in the Diagnostic Management of Soft Tissue Sarcomas of Musculoskeletal Origin Publisher Pubmed



Katal S1 ; Gholamrezanezhad A2 ; Kessler M3 ; Olyaei M1 ; Jadvar H2
Authors
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Authors Affiliations
  1. 1. Tehran University of Medical Sciences (TUMS), Tehran, Iran
  2. 2. Keck School of Medicine, University of Southern California (USC), 1520 San Pablo Street, Suite L1600, Los Angeles, 90033, CA, United States
  3. 3. Case Medical Center, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH, United States

Source: PET Clinics Published:2018


Abstract

Soft tissue sarcomas (STSs) account for less than 1% of adult solid tumors and about 7% of pediatric malignancies, causing 2% of cancer-related deaths. With the advent of PET–computed tomography (CT), the value of (18) fluorine-2-fluoro-2-deoxy-D-glucose (FDG) PET imaging to improve the management of STSs has been explored. FDG PET imaging has been found useful in restaging and treatment response assessment. This article reviews current knowledge and application of FDG PET-CT in initial diagnosis, staging, restaging, treatment response monitoring, and prognosis, with a brief overview of the most common histologic subtypes of STS. © 2018 Elsevier Inc.