A Literature Review of the Studies Concerning Selected Plant-Derived Adaptogens and Their General Function in Body With a Focus on Animal Studies

A Literature Review of the Studies Concerning Selected Plant-Derived Adaptogens and Their General Function in Body With a Focus on Animal Studies Publisher Pubmed

Esmaealzadeh N^{1, 2} ; Iranpanah A^{3, 4} ; Sarris J^{5, 6} ; Rahimi R^{1, 2}

Show Affiliations

1. Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, P.O. Box 1417653761, Iran
2. PhytoPharmacology Interest Group (PPIG), Universal Scientific Education and Research Network (USERN), Tehran, Iran
3. Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran
4. Kermanshah USERN Office, Universal Scientific Education and Research Network (USERN), Kermanshah, Iran
5. NICM Health Research Institute, Western Sydney University, Westmead, NSW, Australia
6. The Florey Institute of Neuroscience and Mental Health & The Professorial Unit, The Melbourne Clinic, Department of Psychiatry, University of Melbourne, Melbourne, VIC, Australia

Source: Phytomedicine Published:2022

Abstract

Background: Adaptogens are generally referred to the substances, mostly found in plants, which non-specifically increase resilience and chances of survival by activation of signaling pathways in affected cells. Purpose: This literature review was conducted to summarize the investigation, until March 2021, on selected adaptogenic plants and plant-derived substances. Study Design: Electronic databases were searched (up to March 2021) for in vitro and animal studies, as well as clinical trials. Moreover, all modes of action connected with the adaptogenic effects of plants and phytochemicals were collected. Methods: The search of relevant studies was performed within electronic databases including Scopus, Science Direct, PubMed, and Cochrane library. The most important keywords were adaptogen, plant, phytochemical, and plant-derived. Results: The most investigated medicinal herbs for their adaptogenic activity are Eleutherococcus senticosus, Panax ginseng, Withania somnifera, Schisandra chinensis, and Rhodiola spp., salidroside, ginsenosides, andrographolide, methyl jasmonate, cucurbitacin R, dichotosin, and dichotosininare are phytochemicals that have shown a considerable adaptogenic activity. Phytochemicals that have been demonstrated adaptogenic properties mainly belong to flavonoids, terpenoids, and phenylpropanoid glycosides. Conclusion: It is concluded that the main modes of action of the selected adaptogenic plants are stress modulatory, antioxidant, anti-fatigue, and physical endurance enhancement. Other properties were nootropic, immunomodulatory, cardiovascular, and radioprotective activities. © 2022

Experts (# of related papers)

View all Related Experts

Kurosh Djafarian (1)

Zahra Vahabi (1)

Style	Citing Format
MLA	Esmaealzadeh N, et al.. "A Literature Review of the Studies Concerning Selected Plant-Derived Adaptogens and Their General Function in Body With a Focus on Animal Studies." Phytomedicine, vol. 105, no. , 2022, pp. -.
APA	Esmaealzadeh N, Iranpanah A, Sarris J, Rahimi R (2022). A Literature Review of the Studies Concerning Selected Plant-Derived Adaptogens and Their General Function in Body With a Focus on Animal Studies. Phytomedicine, 105(), -.
Chicago	Esmaealzadeh N, Iranpanah A, Sarris J, Rahimi R. "A Literature Review of the Studies Concerning Selected Plant-Derived Adaptogens and Their General Function in Body With a Focus on Animal Studies." Phytomedicine 105, no. (2022): -.
Harvard	Esmaealzadeh N et al. (2022) 'A Literature Review of the Studies Concerning Selected Plant-Derived Adaptogens and Their General Function in Body With a Focus on Animal Studies', Phytomedicine, 105(), pp. -.
Vancouver	Esmaealzadeh N, Iranpanah A, Sarris J, Rahimi R. A Literature Review of the Studies Concerning Selected Plant-Derived Adaptogens and Their General Function in Body With a Focus on Animal Studies. Phytomedicine. 2022;105():-.
BibTex	@article{ author = {Esmaealzadeh N and Iranpanah A and Sarris J and Rahimi R}, title = {A Literature Review of the Studies Concerning Selected Plant-Derived Adaptogens and Their General Function in Body With a Focus on Animal Studies}, journal = {Phytomedicine}, volume = {105}, number = {}, pages = {-}, year = {2022} }
RIS	TY - JOUR AU - Esmaealzadeh N AU - Iranpanah A AU - Sarris J AU - Rahimi R TI - A Literature Review of the Studies Concerning Selected Plant-Derived Adaptogens and Their General Function in Body With a Focus on Animal Studies JO - Phytomedicine VL - 105 IS - SP - EP - PY - 2022 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract