Waist-To-Hip Ratio As a Contributor Associated With Higher Atherosclerotic Cardiovascular Disease Risk Assessment in Patients With Diabetes: A Cross-Sectional Study Publisher Pubmed



Rafsanjani K¹ ; Rabizadeh S¹ ; Ebrahimiantabrizi A² ; Asadibideshki Z² ; Yadegar A¹ ; Esteghamati A¹ ; Nakhjavani M¹ ; Reyhan SK¹ Show Affiliations
Source: BMC Cardiovascular Disorders Published:2024

Abstract

Introduction: This study aimed to identify the factors most strongly associated with an increased atherosclerotic cardiovascular disease (ASCVD) risk score in patients with type 2 diabetes (T2D). Methods: This cross-sectional study included 4698 patients with T2D over an 11-year period (2010–2021). Patients were categorized into four groups based on their 10-year ASCVD risk score (< 5%, 5–7.5%, 7.5–20%, and > 20%). Multinominal regression analysis was used to evaluate the association between various modifiable and non-modifiable risk factors and the ASCVD risk score. Results: Of the patients, 35.9% had a 10-year ASCVD risk score below 5%, 12.6% had a score between 5% and 7.5%, 30.8% had a score between 7.5% and 20%, and 19.7% had a score above 20%. Higher ASCVD risk scores were significantly associated with elevated waist-to-hip ratio (WHR > 0.93), pulse pressure, uric acid, triglycerides, and decreased glomerular filtration rate (all p-values < 0.05). WHR demonstrated the strongest association with higher ASCVD risk scores (OR: 4.55, 95% CI: 2.94–7.03, p < 0.001) when comparing patients with ASCVD scores > 5% to those with scores < 5%. Conclusion: WHR was independently associated with higher ASCVD risk scores in patients with T2D. Incorporating WHR, along with traditional risk factors, could improve ASCVD risk assessments in this population. © The Author(s) 2024.