Nanovehicles for Co-Delivery of Anticancer Agents

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):

Share this content! On (X network) By

Nanovehicles for Co-Delivery of Anticancer Agents Publisher Pubmed

Zeinali M^{1, 2} ; Abbaspourravasjani S^{2, 3} ; Ghorbani M⁴ ; Babazadeh A⁵ ; Soltanfam T¹ ; Santos AC^{6, 7} ; Hamishehkar H² ; Hamblin MR^{8, 9, 10}

Show Affiliations

1. Student Research Committee and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
2. Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
3. Student's Scientific Research Center and Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
4. Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
5. Department of Biomedical Sciences, Faculty of Medicine, Health, and Human Sciences, Macquarie University, Sydney, 2109, NSW, Australia
6. Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal
7. REQUIMTE/LAQV, Group of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal
8. Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, 02114, MA, United States
9. Department of Dermatology, Harvard Medical School, Boston, 02115, MA, United States
10. Laser Research Centre, Faculty of Health Science, University of Johannesburg, Doornfontein, 2028, South Africa

Source: Drug Discovery Today Published:2020

Abstract

Using nanovehicles for co-delivery of two or more anticancer agents shows benefits including: synergistic effects, promoting apoptosis pathways, reduction of toxicity and side effects, and overcoming multidrug resistance. © 2020 Elsevier Ltd; Effective cancer treatment remains a significant challenge in human healthcare. Although many different types of cancer therapy have been tested, scientists have now concluded that combinations of drugs, or drugs plus gene therapy, can target multiple pathways to fight cancer. Nanovehicles can increase drug uptake inside tumor cells, improve biodistribution and accumulation at tumor sites. The ability to deliver two or more anticancer drugs, genes, among others, at the same time and place will increase therapeutic effects while decreasing side effects and reducing the risk of multidrug resistance. This review discusses the advantages of nano-based co-delivery methods in cancer therapy, summarizes the common types of nanovehicles and their preparation methods, and covers some recent co-delivery studies in detail. © 2020 Elsevier Ltd

Related Docs

View other Related Docs

1. Lipid-Based Nanoparticles for the Targeted Delivery of Anticancer Drugs: A Review, Current Drug Delivery (2022)

2. Co-Delivery Systems: Hope for Clinical Application?, Drug Delivery and Translational Research (2022)

3. Nanoparticulate Systems for Combination Therapies of Lung Cancer: A Review, Journal of Nanoparticle Research (2025)

4. Liposomal Formulation for Co-Delivery of Paclitaxel and Lapatinib, Preparation, Characterization and Optimization, Journal of Liposome Research (2016)

5. Nano-Enabled Plant-Based Colloidal Delivery Systems for Bioactive Agents in Foods: Design, Formulation, and Application, Advances in Colloid and Interface Science (2022)

6. Recent Progress in the Application of Plant-Based Colloidal Drug Delivery Systems in the Pharmaceutical Sciences, Advances in Colloid and Interface Science (2022)

7. Polymeric Nanoparticles for Dna Vaccine-Based Cancer Immunotherapy: A Review, Biotechnology Letters (2023)

8. Synergistic Effect of Curcumin and Tamoxifen Loaded in Ph-Responsive Gemini Surfactant Nanoparticles on Breast Cancer Cells, BMC Complementary Medicine and Therapies (2024)

Experts (# of related papers)

View all Related Experts

Farid Dorkoosh (4)

Rassoul Dinarvand (2)

Other Related Docs

9. Lipid-Based Nanoparticles for Drug Delivery Systems, Characterization and Biology of Nanomaterials for Drug Delivery: Nanoscience and Nanotechnology in Drug Delivery (2018)

10. Encapsulation for General Cancer Treatment, Principles of Biomaterials Encapsulation: Volume 2 (2023)

11. In-Vitro Tumor Microenvironment Models Containing Physical and Biological Barriers for Modelling Multidrug Resistance Mechanisms and Multidrug Delivery Strategies, Journal of Controlled Release (2021)

12. Functionalized Liposomes As a Potential Drug Delivery Systems for Colon Cancer Treatment: A Systematic Review, International Journal of Biological Macromolecules (2024)

13. Enhancing the Cytotoxic Effects of Carboplatin and Cisplatin on Liposomes in Oral Cancer Cells With Curcumin, Asian Pacific Journal of Cancer Biology (2024)

14. A Concise Review on Cancer Treatment Methods and Delivery Systems, Journal of Drug Delivery Science and Technology (2019)

15. Biopolymeric Nanoparticles, Pickering Nanoemulsions and Nanophytosomes for Loading of Zataria Multiflora Essential Oil As a Biopreservative; [نانوذرات بیوپلیمری، نانوامولسیون های جمع کننده و نانوفیتوزوم ها برای بارگیری اسانسآویشن شیرازی 1 بهعنوان نگهدارنده زیستی], Applied Food Biotechnology (2023)

16. Hyaluronic Acid-Coated Liposomes for Targeted Delivery of Paclitaxel, In-Vitro Characterization and In-Vivo Evaluation, Journal of Controlled Release (2016)

17. Enhancing Sirna Cancer Therapy: Multifaceted Strategies With Lipid and Polymer-Based Carrier Systems, International Journal of Pharmaceutics (2024)

18. Apigenin As Tumor Suppressor in Cancers: Biotherapeutic Activity, Nanodelivery, and Mechanisms With Emphasis on Pancreatic Cancer, Frontiers in Chemistry (2020)

19. Simultaneous Controlled Release of 5-Fu, Dox and Ptx From Chitosan/Pla/5-Fu/G-C3n4-Dox/G-C3n4-Ptx Triaxial Nanofibers for Breast Cancer Treatment in Vitro, Colloids and Surfaces B: Biointerfaces (2019)

20. Hyaluronic Acid-Based Drug Nanocarriers As a Novel Drug Delivery System for Cancer Chemotherapy: A Systematic Review, DARU# Journal of Pharmaceutical Sciences (2021)

21. Ph-Responsive, Adorned Nanoniosomes for Codelivery of Cisplatin and Epirubicin: Synergistic Treatment of Breast Cancer, ACS Applied Bio Materials (2022)

22. The Effects of Ovalbumin on Proliferation, Migration, and Stemness Properties of Chemoresistant Sw480 Colon Cancer Cells, Nutrition and Cancer (2022)

Style	Citing Format
MLA	Zeinali M, et al.. "Nanovehicles for Co-Delivery of Anticancer Agents." Drug Discovery Today, vol. 25, no. 8, 2020, pp. 1416-1430.
APA	Zeinali M, Abbaspourravasjani S, Ghorbani M, Babazadeh A, Soltanfam T, Santos AC, Hamishehkar H, Hamblin MR (2020). Nanovehicles for Co-Delivery of Anticancer Agents. Drug Discovery Today, 25(8), 1416-1430.
Chicago	Zeinali M, Abbaspourravasjani S, Ghorbani M, Babazadeh A, Soltanfam T, Santos AC, Hamishehkar H, Hamblin MR. "Nanovehicles for Co-Delivery of Anticancer Agents." Drug Discovery Today 25, no. 8 (2020): 1416-1430.
Harvard	Zeinali M et al. (2020) 'Nanovehicles for Co-Delivery of Anticancer Agents', Drug Discovery Today, 25(8), pp. 1416-1430.
Vancouver	Zeinali M, Abbaspourravasjani S, Ghorbani M, Babazadeh A, Soltanfam T, Santos AC, et al.. Nanovehicles for Co-Delivery of Anticancer Agents. Drug Discovery Today. 2020;25(8):1416-1430.
BibTex	@article{ author = {Zeinali M and Abbaspourravasjani S and Ghorbani M and Babazadeh A and Soltanfam T and Santos AC and Hamishehkar H and Hamblin MR}, title = {Nanovehicles for Co-Delivery of Anticancer Agents}, journal = {Drug Discovery Today}, volume = {25}, number = {8}, pages = {1416-1430}, year = {2020} }
RIS	TY - JOUR AU - Zeinali M AU - Abbaspourravasjani S AU - Ghorbani M AU - Babazadeh A AU - Soltanfam T AU - Santos AC AU - Hamishehkar H AU - Hamblin MR TI - Nanovehicles for Co-Delivery of Anticancer Agents JO - Drug Discovery Today VL - 25 IS - 8 SP - 1416 EP - 1430 PY - 2020 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract