Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Recent Progress in the Application of Plant-Based Colloidal Drug Delivery Systems in the Pharmaceutical Sciences Publisher Pubmed



Mohammadi K1 ; Sani MA2 ; Azizilalabadi M3 ; Mcclements DJ4, 5
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Division of Food Safety and Hygiene, Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Research Center for Environmental Determinants of Health (RCEDH), Kermanshah University of Medical Sciences, Kermanshah, Iran
  4. 4. Department of Food Science, University of Massachusetts Amherst, Amherst, 01003, MA, United States
  5. 5. Department of Food Science & Bioengineering, Zhejiang Gongshang University, 18 Xuezheng Street, Hangzhou, 310018, Zhejiang, China

Source: Advances in Colloid and Interface Science Published:2022


Abstract

The potential for utilizing plant-derived components, such as plant proteins, polysaccharides, lipids, and phospholipids, to create targeted drug delivery systems has been demonstrated in recent years. These colloidal delivery systems can encapsulate, protect, and release pharmaceuticals, vitamins, and nutraceuticals, thereby improving their bioavailability and efficacy. Moreover, they have the potential to reduce the side effects associated with some conventional drug formulations, while still achieving controlled or targeted delivery of pharmaceutical agents by various administration routes, including oral, nasal, dermal and inhalation. The pharmacokinetic and pharmacodynamic profiles of drugs can be modulated by altering the composition, dimensions, and structure of drug formulations created using plant-based colloidal delivery systems. The utilization of plant-derived ingredients may also reduce the environmental impact and improve the sustainability of drug formulations. Initially, we provide an overview of the general characteristics and requirements of drug delivery systems. The opportunities and challenges of using plant-derived components to fabricate colloidal particles for drug delivery applications is then discussed. Finally, potential clinical applications of plant-based delivery drug systems are reviewed. © 2022 Elsevier B.V.
Related Docs
View other Related Docs
1. Nano-Enabled Plant-Based Colloidal Delivery Systems for Bioactive Agents in Foods: Design, Formulation, and Application, Advances in Colloid and Interface Science (2022)
2. Plant Protein-Based Hydrophobic Fine and Ultrafine Carrier Particles in Drug Delivery Systems, Critical Reviews in Biotechnology (2018)
3. Biopharmaceutical and Pharmacokinetic Aspects of Nanocarrier-Mediated Oral Delivery of Poorly Soluble Drugs, Journal of Drug Delivery Science and Technology (2021)
4. Status and Future Scope of Plant-Based Green Hydrogels in Biomedical Engineering, Applied Materials Today (2019)
5. The Colorful World of Carotenoids: A Profound Insight on Therapeutics and Recent Trends in Nano Delivery Systems, Critical Reviews in Food Science and Nutrition (2022)
6. Nanovehicles for Co-Delivery of Anticancer Agents, Drug Discovery Today (2020)
7. Recent Progresses in the Delivery of Β-Carotene: From Nano/Microencapsulation to Bioaccessibility, Advances in Colloid and Interface Science (2022)
8. Encapsulation: Controlled Drug Delivery, Principles of Biomaterials Encapsulation: Volume 2 (2023)
Experts (# of related papers)
View all Related Experts
Rassoul Dinarvand (4)
Farid Dorkoosh (3)
Other Related Docs
9. Oral Delivery of Therapeutic Peptides and Proteins: Technology Landscape of Lipid-Based Nanocarriers, Advanced Drug Delivery Reviews (2022)
10. Diatoms With Invaluable Applications in Nanotechnology, Biotechnology, and Biomedicine: Recent Advances, ACS Biomaterials Science and Engineering (2021)
11. Chemotherapeutic Effects of Apigenin in Breast Cancer: Preclinical Evidence and Molecular Mechanisms; Enhanced Bioavailability by Nanoparticles, Biotechnology Reports (2022)
12. Ultrasound-Modified Protein-Based Colloidal Particles: Interfacial Activity, Gelation Properties, and Encapsulation Efficiency, Advances in Colloid and Interface Science (2022)
13. Recent Developments of Nanostructures for the Ocular Delivery of Natural Compounds, Frontiers in Chemistry (2022)
14. Curcumin in Liver Diseases: A Systematic Review of the Cellular Mechanisms of Oxidative Stress and Clinical Perspective, Nutrients (2018)
15. A State-Of-The-Art Review on Solid Lipid Nanoparticles As a Nanovaccines Delivery System, Journal of Drug Delivery Science and Technology (2023)
16. Ph-Responsive, Adorned Nanoniosomes for Codelivery of Cisplatin and Epirubicin: Synergistic Treatment of Breast Cancer, ACS Applied Bio Materials (2022)
17. A Concise Review on Cancer Treatment Methods and Delivery Systems, Journal of Drug Delivery Science and Technology (2019)
18. Nano-Particles’ Benefits for Colon Cancer Effective Therapy: A Review of Recent Advancements and Clinical Trials, International Journal of Polymeric Materials and Polymeric Biomaterials (2024)
19. Value-Added Utilization of Fruit and Vegetable Processing By-Products for the Manufacture of Biodegradable Food Packaging Films, Food Chemistry (2023)
20. Resveratrol in Breast Cancer Treatment: From Cellular Effects to Molecular Mechanisms of Action, Cellular and Molecular Life Sciences (2022)
21. Temperature-Responsive Smart Nanocarriers for Delivery of Therapeutic Agents: Applications and Recent Advances, ACS Applied Materials and Interfaces (2016)
22. Application of Nano-Based Systems for Drug Delivery and Targeting: A Review, Journal of Nanoparticle Research (2020)
23. Design and Evaluation of a Novel Nanodrug Delivery System for Reducing the Side Effects of Clomiphene Citrate on Endometrium, DARU# Journal of Pharmaceutical Sciences (2020)
24. Preparation and In-Vitro Hematological Evaluation of Chlorambucil Loaded Lipid Nanoparticles, International Journal of Drug Delivery Technology (2021)
25. Attenuation of Aggregatibacter Actinomycetemcomitans Virulence Using Curcumin-Decorated Nanophytosomes-Mediated Photo-Sonoantimicrobial Chemotherapy, Scientific Reports (2021)
26. Cross-Linked Polysaccharides in Drug Delivery, Tailor-Made Polysaccharides in Drug Delivery (2022)
27. Design and Optimization of Noscapine Nanosuspensions and Study of Its Cytotoxic Effect, Journal of Biomolecular Structure and Dynamics (2019)
28. Targeted Ph- and Redox-Responsive Aus/Micelles With Low Cmc for Highly Efficient Sonodynamic Therapy of Metastatic Breast Cancer, Biomaterials Advances (2024)
29. Anti-Cancer Drug Delivery Using Carbohydrate-Based Polymers, Current Pharmaceutical Design (2017)
30. Recent Advances on Biomedical Applications of Pectin-Containing Biomaterials, International Journal of Biological Macromolecules (2022)
31. Advances in Plant Gum Polysaccharides; Sources, Techno-Functional Properties, and Applications in the Food Industry - a Review, International Journal of Biological Macromolecules (2022)
32. Multifunctional 3D Hierarchical Bioactive Green Carbon-Based Nanocomposites, ACS Sustainable Chemistry and Engineering (2021)
33. Lipid-Based Nanoparticles for the Targeted Delivery of Anticancer Drugs: A Review, Current Drug Delivery (2022)
34. Lipid-Based Nanoparticles for Drug Delivery Systems, Characterization and Biology of Nanomaterials for Drug Delivery: Nanoscience and Nanotechnology in Drug Delivery (2018)
35. Brain Delivery of Curcumin Using Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Preparation, Optimization, and Pharmacokinetic Evaluation, ACS Chemical Neuroscience (2019)
36. The Potential Use of Antibiotics Against Helicobacter Pylori Infection: Biopharmaceutical Implications, Frontiers in Pharmacology (2022)
37. Nobiletin in Cancer Therapy; Mechanisms and Therapy Perspectives, Current Pharmaceutical Design (2023)
38. Release Behavior and Signaling Effect of Vitamin D3 in Layered Double Hydroxides-Hydroxyapatite/Gelatin Bone Tissue Engineering Scaffold: An in Vitro Evaluation, Colloids and Surfaces B: Biointerfaces (2017)
39. Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery, Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (2015)
40. Encapsulation of Ritonavir in Solid Lipid Nanoparticles: In-Vitro Anti-Hiv-1 Activity Using Lentiviral Particles, Journal of Pharmacy and Pharmacology (2017)
41. Toxicity and Biocompatibility of Nanomaterials: In Vivo Studies, Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance (2022)
42. Ph-Responsive Chitosan-Adorned Niosome Nanocarriers for Co-Delivery of Drugs for Breast Cancer Therapy, ACS Applied Nano Materials (2022)
43. Biological and Thermodynamic Stabilization of Lipid-Based Delivery Systems Through Natural Biopolymers; Controlled Release and Molecular Dynamics Simulations, Critical Reviews in Food Science and Nutrition (2023)