Comparison of Efficacy of Granisetron and Promethazine in Control of Hyperemesis Gravidarum

Comparison of Efficacy of Granisetron and Promethazine in Control of Hyperemesis Gravidarum Publisher

Aleyasin A¹ ; Saffarieh E⁵ ; Torkamandi H² ; Hanafi S² ; Sadeghi F² ; Mahdavi A¹ ; Bahmaei F¹ ; Javadi M^{3, 4}

Show Affiliations

1. Obstetrics and Gynecology Department, Dr. Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
2. Pharmaceutical Care Department, Dr. Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
3. Clinical Pharmacy Department, College of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
4. Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, Iran
5. Abnormal uterine Bleeding Research Center, Semnan University of Medical Sciences, Semnan, Iran

Source: Journal of Obstetrics and Gynecology of India Published:2016

Abstract

Purpose: Hyperemesis gravidarum is the third leading cause of hospitalization during pregnancy. 5-HT3-receptor antagonists are the most effective against chemotherapy-induced nausea and vomiting and radiation. This randomized study aimed to compare and evaluate the efficacies of granisetron and promethazine for controlling nausea and vomiting of pregnancy. Methods: The included patients were administered (oral and intravenous) granisetron and promethazine randomly. The patients were evaluated for nausea and vomiting by a senior gynecology resident blinded to designated drugs. Results: This study revealed that granisetron significantly decreased nausea and vomiting in pregnant women (pi¿½

Style	Citing Format
MLA	Aleyasin A, et al.. "Comparison of Efficacy of Granisetron and Promethazine in Control of Hyperemesis Gravidarum." Journal of Obstetrics and Gynecology of India, vol. 66, no. 6, 2016, pp. 409-414.
APA	Aleyasin A, Saffarieh E, Torkamandi H, Hanafi S, Sadeghi F, Mahdavi A, Bahmaei F, Javadi M (2016). Comparison of Efficacy of Granisetron and Promethazine in Control of Hyperemesis Gravidarum. Journal of Obstetrics and Gynecology of India, 66(6), 409-414.
Chicago	Aleyasin A, Saffarieh E, Torkamandi H, Hanafi S, Sadeghi F, Mahdavi A, Bahmaei F, Javadi M. "Comparison of Efficacy of Granisetron and Promethazine in Control of Hyperemesis Gravidarum." Journal of Obstetrics and Gynecology of India 66, no. 6 (2016): 409-414.
Harvard	Aleyasin A et al. (2016) 'Comparison of Efficacy of Granisetron and Promethazine in Control of Hyperemesis Gravidarum', Journal of Obstetrics and Gynecology of India, 66(6), pp. 409-414.
Vancouver	Aleyasin A, Saffarieh E, Torkamandi H, Hanafi S, Sadeghi F, Mahdavi A, et al.. Comparison of Efficacy of Granisetron and Promethazine in Control of Hyperemesis Gravidarum. Journal of Obstetrics and Gynecology of India. 2016;66(6):409-414.
BibTex	@article{ author = {Aleyasin A and Saffarieh E and Torkamandi H and Hanafi S and Sadeghi F and Mahdavi A and Bahmaei F and Javadi M}, title = {Comparison of Efficacy of Granisetron and Promethazine in Control of Hyperemesis Gravidarum}, journal = {Journal of Obstetrics and Gynecology of India}, volume = {66}, number = {6}, pages = {409-414}, year = {2016} }
RIS	TY - JOUR AU - Aleyasin A AU - Saffarieh E AU - Torkamandi H AU - Hanafi S AU - Sadeghi F AU - Mahdavi A AU - Bahmaei F AU - Javadi M TI - Comparison of Efficacy of Granisetron and Promethazine in Control of Hyperemesis Gravidarum JO - Journal of Obstetrics and Gynecology of India VL - 66 IS - 6 SP - 409 EP - 414 PY - 2016 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract