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Tuberculosis and Diabetes Mellitus in Northwest of Iran Publisher Pubmed



Ozma MA1 ; Rashedi J2 ; Poor BM3 ; Vegari A4 ; Asgharzadeh V5 ; Kafil HS6 ; Kazemi A5 ; Sahebi L7 ; Asgharzadeh M8
Authors
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Authors Affiliations
  1. 1. Department of Microbiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
  2. 2. Tuberculosis and Lung Disease Research Center, Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, Iran
  3. 3. Department of Laboratory Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
  4. 4. Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
  5. 5. Infectious and Tropical Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  6. 6. Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  7. 7. Maternal-Fetal and Neonatal Research Center, Tehran University of Medical Science, Tehran, Iran
  8. 8. Biotechnology Research Center, Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, Iran

Source: Infectious Disorders - Drug Targets Published:2020


Abstract

Background: Planning for control of tuberculosis would need to screen and identify individuals susceptible to TB. Due to the weakness of immune system in diabetic patients, it is more likely for them to reactivate latent TB infection. Regarding the increasing number of diabetics in the community, in this study efforts have been made to estimate the frequency of individuals who have tuberculosis and diabetes mellitus (TB-DM) simultaneously, as it could help making preventive decisions to reduce TB in this part of Iran. Materials and Methods: In this study, 329 cases of confirmed TB patients were divided into two groups of diabetic and non-diabetic, then demographic information and clinical variables have been compared between the two groups. Results: Among the examined subjects, 47 patients (14.29 %) had suffered from diabetes mellitus and tuberculosis. All of the DM patients had pulmonary tuberculosis and 87.23% of them were over the age of 50. Conclusion: Majority of DM-TB patients were over 50 years of age and also more than half of them were women. So it seems that for DM women over the age of 50, to detect tuberculosis, screening tests such as PPD may be necessary. © 2020 Bentham Science Publishers.