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Global, Regional, and National Incidence of Six Major Immune-Mediated Inflammatory Diseases: Findings From the Global Burden of Disease Study 2019 Publisher



Wu D1 ; Jin Y2 ; Xing Y3 ; Abate MD6 ; Abbasian M7, 12 ; Abbasikangevari M33 ; Abbasikangevari Z13, 33 ; Abdallah F62 ; Abdelmasseh M64 ; Abdollahifar MA65 ; Abdulah DM66 ; Abedi A67, 68 ; Abedi V70, 71 ; Abidi H72 Show All Authors
Authors
  1. Wu D1
  2. Jin Y2
  3. Xing Y3
  4. Abate MD6
  5. Abbasian M7, 12
  6. Abbasikangevari M33
  7. Abbasikangevari Z13, 33
  8. Abdallah F62
  9. Abdelmasseh M64
  10. Abdollahifar MA65
  11. Abdulah DM66
  12. Abedi A67, 68
  13. Abedi V70, 71
  14. Abidi H72
  15. Aboagye RG74
  16. Abolhassani H34, 76
  17. Abuabara K77
  18. Abyadeh M78
  19. Addo IY79, 80
  20. Adeniji KN81
  21. Adepoju AV83, 84
  22. Adesina MA86
  23. Adnani QES91
  24. Afarideh M35, 92
  25. Aghamiri S14
  26. Agodi A93
  27. Agrawal A94, 95
  28. Arriagada CEA96
  29. Ahmad A15, 97
  30. Ahmad D100, 101
  31. Ahmad S102, 103
  32. Ahmad S102, 103
  33. Ahmadi A15, 104
  34. Ahmed A106, 107, 108, 110
  35. Ahmed A106, 107, 108, 110
  36. Aithala JP111
  37. Ajadi AA112, 113
  38. Ajami M16, 114
  39. Akbarzadehkhiavi M115
  40. Alahdab F122
  41. Albataineh MT123
  42. Alemi S125
  43. Algheethi AAS126, 128
  44. Ali L129, 441
  45. Alif SM130
  46. Almazan JU133
  47. Almustanyir S135, 136
  48. Alqahtani JS137
  49. Alqasmi I138
  50. Altaf IUK139
  51. Alvisguzman N140, 141
  52. Alviszakzuk NJ142, 143
  53. Alworafi YM144, 145
  54. Aly H146
  55. Amani R148, 149
  56. Amu H75
  57. Amusa GA157, 158
  58. Andrei CL159
  59. Ansar A161, 162
  60. Ansariniya H17, 163
  61. Anyasodor AE164
  62. Arabloo J165
  63. Arefnezhad R150
  64. Arulappan J171
  65. Asgharijafarabadi M131, 172
  66. Ashraf T173
  67. Atata JA176
  68. Athari SS177
  69. Atlaw D179
  70. Atout MMW180
  71. Aujayeb A181
  72. Awan AT182, 183
  73. Ayatollahi H165, 166
  74. Azadnajafabad S33
  75. Azzam AY184, 185
  76. Badawi A186, 187
  77. Badiye AD189
  78. Bagherieh S190
  79. Baig AA174
  80. Bantie BB193
  81. Barchitta M93
  82. Bardhan M196, 197
  83. Barkercollo SL199
  84. Baroneadesi F200
  85. Batra K201
  86. Bayileyegn NS203
  87. Behnoush AH205
  88. Belgaumi UI206
  89. Bemanalizadeh M37, 191
  90. Bensenor IM208
  91. Beyene KA210, 211
  92. Bhagavathula AS212
  93. Bhardwaj P213, 214
  94. Bhaskar S216, 217
  95. Bhat AN218
  96. Bitaraf S221
  97. Bitra VR222
  98. Boloor A219
  99. Bora K223
  100. Botelho JS224
  101. Buchbinder R132, 225
  102. Calina D226
  103. Camera LA227, 229
  104. Carvalho AF230
  105. Chan JSK232
  106. Chattu VK188, 233
  107. Abebe EC194
  108. Chichagi F38
  109. Choi S235
  110. Chou TC236
  111. Chu DT238
  112. Coberly K239
  113. Costa VM241
  114. Couto RAS242
  115. Cruzmartins N243, 247
  116. Dadras O249, 250
  117. Dai X239, 240
  118. Damiani G252, 254
  119. Dascalu AM160, 257
  120. Dashti M116
  121. Debela SA258
  122. Dellavalle RP259, 260
  123. Demetriades AK261, 266
  124. Demlash AA267
  125. Deng X270
  126. Desai HD271, 272
  127. Desai R271, 272
  128. Dewan SMR273, 274
  129. Dey S275
  130. Dharmaratne SD240, 277, 278
  131. Diaz D280, 281
  132. Dibas M282
  133. Dinisoliveira RJ244, 283
  134. Diress M284
  135. Do TC286
  136. Doan DK288
  137. Dodangeh M167, 289
  138. Dodangeh M167, 289
  139. Dongarwar D290
  140. Dube J292
  141. Dziedzic AM293
  142. Eddra A294
  143. Edinur HA295
  144. Eissazade N167
  145. Ekholuenetale M87, 88
  146. Ekundayo TC297
  147. Elemam NM298
  148. Elhadi M302
  149. Elmehrath AO8, 63
  150. Elmeligy OAA303, 307
  151. Emamverdi M309
  152. Emeto TI310
  153. Esayas HL268
  154. Eshetu HB285
  155. Etaee F312
  156. Fagbamigbe AF87, 316
  157. Faghani S39
  158. Fakhradiyev IR317
  159. Fatehizadeh A192
  160. Fathi M18
  161. Feizkhah A318
  162. Fekadu G4, 319
  163. Fereidouni M321, 322
  164. Fereshtehnejad SM324, 326
  165. Fernandes JC327
  166. Ferrara P328
  167. Fetensa G320
  168. Filip I330, 331
  169. Fischer F332
  170. Foroutan B334
  171. Foroutan M335, 336
  172. Fukumoto T337
  173. Ganesan B338, 339
  174. Gemeda BNB340
  175. Ghamari SH13, 33
  176. Ghasemi M19, 20
  177. Gholamalizadeh M21
  178. Gill TK341
  179. Gillum RF343, 344
  180. Goldust M313
  181. Golechha M345
  182. Goleij P346
  183. Golinelli D347
  184. Goudarzi H348, 349
  185. Guan SY350
  186. Guo Y351, 633
  187. Gupta B231, 352, 353
  188. Gupta VB231, 352, 353
  189. Gupta VK231, 352, 353
  190. Haddadi R355
  191. Hadi NR357
  192. Halwani R299, 300
  193. Haque S358
  194. Hasan I361
  195. Hashempour R22
  196. Hassan A62, 325, 362
  197. Hassan TS62, 325, 362
  198. Hassanzadeh S190
  199. Hassen MB239, 363
  200. Haubold J364, 365
  201. Hayat K366, 367
  202. Heidari G105, 368
  203. Heidari M105, 368
  204. Heidarisoureshjani R61
  205. Herteliu C369, 370
  206. Hessami K9, 151
  207. Hezam K371, 372
  208. Hiraike Y373
  209. Holla R374
  210. Hosseini MS117
  211. Huynh HH380
  212. Hwang BF237, 381
  213. Ibitoye SE89
  214. Ilic IM382, 383
  215. Ilic MD382, 383
  216. Iranmehr A40
  217. Iravanpour F152
  218. Ismail NE384, 385
  219. Iwagami M211, 386, 387
  220. Iwu CCD388
  221. Jacob L389, 391
  222. Jafarinia M152
  223. Jafarzadeh A392, 394
  224. Jahankhani K17
  225. Jahrami H396, 397
  226. Jakovljevic M398, 399
  227. Jamshidi E23, 400
  228. Jani CT402
  229. Janodia MD375
  230. Jayapal SK403
  231. Jayaram S404
  232. Jeganathan J218
  233. Jonas JB405, 406
  234. Joseph A407
  235. Joseph N220
  236. Joshua CE408
  237. Vaishali K376
  238. Kaambwa B409, 410
  239. Kabir A168, 411
  240. Kabir Z168, 411
  241. Kadashetti V412
  242. Kaliyadan F413
  243. Kalroozi F414, 415
  244. Kamal VK198, 416
  245. Kandel A417
  246. Kandel H418, 419
  247. Kanungo S420
  248. Karami J41, 421
  249. Karaye IM422
  250. Karimi H42
  251. Kasraei H149, 169
  252. Kazemian S43, 44
  253. Kebede SA423
  254. Keikavoosiarani L424
  255. Keykhaei M33, 45
  256. Khader YS426
  257. Khajuria H427
  258. Khamesipour F46, 428
  259. Khan EA429
  260. Khan IA430
  261. Khan M359, 432, 435
  262. Khan MJ359, 432, 435
  263. Khan MAB359, 432, 435
  264. Khan MA433, 434
  265. Khatatbeh H436, 437
  266. Khatatbeh MM436, 437
  267. Khateri S438
  268. Kashani HRK24
  269. Kim MS439
  270. Kisa A440, 441
  271. Kisa S440, 441, 442
  272. Koh HY443
  273. Kolkhir P333, 444
  274. Korzh O446
  275. Kotnis AL447
  276. Koul PA448
  277. Koyanagi A449
  278. Krishan K450
  279. Kuddus M451
  280. Kulkarni VV452
  281. Kumar N453
  282. Kundu S454, 455
  283. Kurmi OP456, 457
  284. Vecchia CL253
  285. Lahariya C459, 460, 486
  286. Laksono T461, 462, 474
  287. Lam J463, 464
  288. Latief K465, 466
  289. Lauriola P469
  290. Lawal BK470
  291. Le TTT471, 474
  292. Le TTB471, 474
  293. Lee M475, 476
  294. Lee SW477
  295. Lee WC478
  296. Lee YH479
  297. Lenzi J347
  298. Levi M480, 481
  299. Li W314
  300. Ligade VS377
  301. Lim SS239, 240
  302. Liu G482, 483
  303. Liu X147, 255
  304. Llanaj E484, 485
  305. Lo CH486
  306. Machado VS487
  307. Maghazachi AA299
  308. Mahmoud MA488
  309. Mai TA489
  310. Majeed A491
  311. Sanaye PM178
  312. Makram OM492, 493
  313. Rad EM47
  314. Malhotra K494
  315. Malik AA174, 304, 495
  316. Malik I174, 304, 495
  317. Mallhi TH496
  318. Malta DC497
  319. Mansournia MA48
  320. Mantovani LG329, 499
  321. Martorell M501, 502
  322. Masoudi S49
  323. Masoumi SZ356
  324. Mathangasinghe Y503, 504
  325. Mathews E505
  326. Mathioudakis AG506, 507
  327. Maugeri A93
  328. Mayeli M36
  329. Medina JRC508, 509
  330. Meles GG510
  331. Mendes JJ487
  332. Menezes RG514
  333. Mestrovic T239, 515
  334. Michalek IM516, 517
  335. Nogueira De Sa ACMG497
  336. Mihretie ET518
  337. Minh LHN467, 468
  338. Mirfakhraie R25
  339. Mirrakhimov EM519, 520
  340. Misganaw A240, 363
  341. Mohamadkhani A49
  342. Mohamed NS521, 522
  343. Mohammadi F36, 167
  344. Mohammadi S36, 167
  345. Mohammed S523, 524, 525, 526
  346. Mohammed S523, 524, 525, 526
  347. Mohan S360, 527
  348. Mohseni A26
  349. Mokdad AH239, 240
  350. Momtazmanesh S33, 36
  351. Monasta L528
  352. Moni MA529
  353. Moniruzzaman M530
  354. Moradi Y532
  355. Morovatdar N533
  356. Mostafavi E538, 539
  357. Mousavi P33
  358. Mukoro GD540
  359. Mulita A541
  360. Mulu GB542
  361. Murillozamora E543, 544
  362. Musaigwa F545
  363. Mustafa G98, 546
  364. Muthu S547, 548
  365. Nainu F549
  366. Nangia V550
  367. Swamy SN551
  368. Natto ZS10, 305
  369. Perumalsamy N552, 553
  370. Nayak BP427
  371. Nazripanjaki A554
  372. Negash H556
  373. Nematollahi MH393
  374. Nguyen DH558, 559
  375. Nguyen HTH560, 561
  376. Nguyen HQ489
  377. Nguyen PT562
  378. Nguyen VT472
  379. Niazi RK563
  380. Nikolouzakis TK564, 565
  381. Nnyanzi LA566
  382. Noreen M567
  383. Nzoputam CI568
  384. Nzoputam OJ569, 570
  385. Oancea B571
  386. Oh IH572
  387. Okatialiabad H555
  388. Okonji OC573
  389. Okwute PG574, 575
  390. Olagunju AT458, 576
  391. Olatubi MI577
  392. Olufadewa II85, 88
  393. Ordak M578
  394. Otstavnov N580
  395. Owolabi MO90, 581
  396. Mahesh PA582
  397. Padubidri JR583
  398. Pak A311, 531
  399. Pakzad R584
  400. Palladino R491, 585
  401. Pana A586, 587
  402. Pantazopoulos I588, 589
  403. Papadopoulou P590, 591
  404. Pardhan S592
  405. Parthasarathi A431, 593
  406. Pashaei A594
  407. Patel J262, 595
  408. Pathan AR99, 596
  409. Patil S234, 597
  410. Paudel U598, 599
  411. Pawar S315
  412. Pedersini P600
  413. Pensato U601
  414. Pereira DM245
  415. Pereira J111
  416. Pereira MO498
  417. Pereira RB246
  418. Peres MFP209, 602
  419. Perianayagam A276
  420. Perna S603
  421. Petcu IR369
  422. Pezeshki PS50, 51
  423. Pham HT287
  424. Philip AK604
  425. Piradov MA605
  426. Podder I606
  427. Podder V342, 607
  428. Poddighe D134, 608
  429. Prates EJS497
  430. Qattea I256
  431. Radfar A609
  432. Raee P27, 52
  433. Rafiei A610, 611
  434. Raggi A612
  435. Rahim F613
  436. Rahimi M118
  437. Rahimifard M52
  438. Rahimimovaghar V53
  439. Rahman MO161, 378, 614, 615, 616, 617
  440. Rahman MHU161, 378, 614, 615, 616, 617
  441. Rahman M161, 378, 614, 615, 616, 617
  442. Rahman MA161, 378, 614, 615, 616, 617
  443. Rahmani AM618
  444. Rahmani M123, 124
  445. Rahmani S28, 33
  446. Rahmanian V619
  447. Ramasubramani P52, 620
  448. Rancic N621, 622
  449. Rao IR379
  450. Rashedi S54, 623
  451. Rashid AM626
  452. Ravikumar N627
  453. Rawaf S491, 628
  454. Redwan EMM629, 630
  455. Rezaei N33, 34, 35, 631
  456. Rezaei N33, 34, 35, 631
  457. Rezaei N33, 34, 35, 631
  458. Rezaeian M395
  459. Ribeiro D245, 634
  460. Rodrigues M635
  461. Rodriguez JAB636
  462. Roever L637
  463. Romerorodriguez E638
  464. Saad AMA639
  465. Saddik B36, 239, 298
  466. Sadeghian S640
  467. Saeed U641, 642
  468. Safary A119
  469. Safdarian M643, 644
  470. Safi SZ645, 646
  471. Saghazadeh A34
  472. Sagoe D251
  473. Sharifaskari FS299, 301
  474. Sharifaskari NS299, 301
  475. Sahebkar A534, 535
  476. Sahoo H276
  477. Sahraian MA55
  478. Sajid MR647
  479. Sakhamuri S648, 649
  480. Sakshaug JW650, 651
  481. Saleh MA300, 652
  482. Salehi L69, 425, 654
  483. Salehi S69, 425, 654
  484. Farrokhi AS655
  485. Samadzadeh S656, 657
  486. Samargandy S306
  487. Samieefar N28, 632
  488. Samy AM658, 659
  489. Sanadgol N660
  490. Sanjeev RK661
  491. Sawhney M662
  492. Saya GK663
  493. Schuermans A664, 665
  494. Senthilkumaran S666
  495. Sepanlou SG49, 153
  496. Sethi Y667
  497. Shafie M56
  498. Shah H668
  499. Shahid I175, 670
  500. Shahid S175, 670
  501. Shaikh MA671
  502. Sharfaei S672, 673
  503. Sharma M202
  504. Shayan M29, 674
  505. Shehata HS62
  506. Sheikh A11, 263
  507. Shetty JK675
  508. Shin JI676
  509. Shirkoohi R57, 58
  510. Shitaye NA677
  511. Shivakumar KM207
  512. Shivarov V678, 679
  513. Shobeiri P59, 624
  514. Siabani S680, 681
  515. Sibhat MM683
  516. Siddig EE109, 684
  517. Simpson CR264, 685
  518. Sinaei E154
  519. Singh H686
  520. Singh I687
  521. Singh JA688, 689
  522. Singh P691
  523. Singh S215
  524. Siraj MS692
  525. Sohag AAM693
  526. Solanki R694, 695
  527. Solikhah S696
  528. Solomon Y697
  529. Soltanizangbar MS120
  530. Sun J682, 698
  531. Szeto MD699
  532. Tabaresseisdedos R700, 701
  533. Tabatabaei SM536, 537
  534. Tabish M99
  535. Taheri E192
  536. Tahvildari A30
  537. Talaat IM299, 308
  538. Lukenze Tamuzi JJL704, 745
  539. Tan KK705
  540. Tat NY707, 708
  541. Oliaee RT155, 156
  542. Tavasol A31
  543. Temsah MH709
  544. Thangaraju P710
  545. Tharwat S653, 721
  546. Tibebu NS195
  547. Ticoalu JHV711
  548. Tillawi T712
  549. Tiruye TY713, 714
  550. Tiyuri A170, 323
  551. Tovanipalone MR715, 716
  552. Tripathi M718
  553. Tsegay GM719
  554. Tualeka AR720
  555. Ty SS721
  556. Ubah CS82, 722
  557. Ullah S723, 724, 725
  558. Ullah S723, 724, 725
  559. Umair M669, 726
  560. Umakanthan S727
  561. Upadhyay E728
  562. Vahabi SM59
  563. Vaithinathan AG729
  564. Tahbaz SV730, 731
  565. Valizadeh R732
  566. Varthya SB215
  567. Vasankari TJ733, 734
  568. Venketasubramanian N706, 735
  569. Verras GI265, 736
  570. Villafane JH600
  571. Vlassov V737
  572. Vo DC473
  573. Waheed Y738, 739
  574. Waris A740
  575. Welegebrial BG557
  576. Westerman R741
  577. Wickramasinghe DP742
  578. Wickramasinghe ND743
  579. Willekens B744, 746
  580. Woldegeorgis BZ747
  581. Woldemariam M269
  582. Xiao H748, 749
  583. Yada DY239
  584. Yahya G490, 512
  585. Yang L500, 513
  586. Yazdanpanah F60, 121
  587. Yon DK445
  588. Yonemoto N248, 296
  589. You Y354, 418
  590. Zahir M32
  591. Zaidi SS228
  592. Zangiabadian M28
  593. Zare I717
  594. Zeineddine MA291
  595. Zemedikun DT690, 703
  596. Zeru NG204, 511
  597. Zhang C401, 625
  598. Zhao H390
  599. Zhong C5
  600. Zielinska M579
  601. Zoladl M73
  602. Zumla A127, 702
  603. Guo C351, 633
  604. Tam L2

Source: eClinicalMedicine Published:2023


Abstract

Background: The causes for immune-mediated inflammatory diseases (IMIDs) are diverse and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to investigate the pattern and trend of IMIDs from 1990 to 2019. Methods: We collected detailed information on six major causes of IMIDs, including asthma, inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, psoriasis, and atopic dermatitis, between 1990 and 2019, derived from the Global Burden of Disease study in 2019. The average annual percent change (AAPC) in number of incidents and age standardized incidence rate (ASR) on IMIDs, by sex, age, region, and causes, were calculated to quantify the temporal trends. Findings: In 2019, rheumatoid arthritis, atopic dermatitis, asthma, multiple sclerosis, psoriasis, inflammatory bowel disease accounted 1.59%, 36.17%, 54.71%, 0.09%, 6.84%, 0.60% of overall new IMIDs cases, respectively. The ASR of IMIDs showed substantial regional and global variation with the highest in High SDI region, High-income North America, and United States of America. Throughout human lifespan, the age distribution of incident cases from six IMIDs was quite different. Globally, incident cases of IMIDs increased with an AAPC of 0.68 and the ASR decreased with an AAPC of −0.34 from 1990 to 2019. The incident cases increased across six IMIDs, the ASR of rheumatoid arthritis increased (0.21, 95% CI 0.18, 0.25), while the ASR of asthma (AAPC = −0.41), inflammatory bowel disease (AAPC = −0.72), multiple sclerosis (AAPC = −0.26), psoriasis (AAPC = −0.77), and atopic dermatitis (AAPC = −0.15) decreased. The ASR of overall and six individual IMID increased with SDI at regional and global level. Countries with higher ASR in 1990 experienced a more rapid decrease in ASR. Interpretation: The incidence patterns of IMIDs varied considerably across the world. Innovative prevention and integrative management strategy are urgently needed to mitigate the increasing ASR of rheumatoid arthritis and upsurging new cases of other five IMIDs, respectively. Funding: The Global Burden of Disease Study is funded by the Bill and Melinda Gates Foundation. The project funded by Scientific Research Fund of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital ( 2022QN38). © 2023 The Author(s)
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