A Rare Case of Ectopic Pituitary Adenoma Originating From the Third Ventricle Floor: Surgical Approach and Outcomes

A Rare Case of Ectopic Pituitary Adenoma Originating From the Third Ventricle Floor: Surgical Approach and Outcomes Publisher

Sharifi G^{1, 2} ; Paraandavaji E² ; Naghizadeh S^{2, 3} ; Nilipour Y^{4, 5} ; Kazemi MA^{6, 7} ; Ebrahimpur M⁸ ; Jafari A² ; Taghizadehhesary F^{9, 10}

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1. Department of Neurosurgery, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iraq
2. Skull Base Research Center, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iraq
3. Functional Neurosurgery Research Center, Shohada Tajrish Comprehensive Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iraq
4. Pediatric Pathology Research Center, Research Institute for Children's Health, Shahid Beheshti University of Medical Sciences, Tehran, Iraq
5. Neuromuscular Research Center, Tehran University of Medical Sciences, Iraq
6. Department of Radiology, Amiralam Hospital, Tehran University of Medical Sciences, Tehran, Iraq
7. Department of Radiology, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Medical Imaging Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iraq
8. Elderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iraq
9. ENT and Head and Neck Research Center, The Five Senses Health Institute, School of Medicine, Iran University of Medical Sciences, Tehran, Iraq
10. Radiation Oncology Department, Iran University of Medical Sciences, Tehran, Iraq

Source: Interdisciplinary Neurosurgery: Advanced Techniques and Case Management Published:2025

Abstract

Introduction: Ectopic pituitary adenomas (EPAs) are uncommon tumors originating outside the sella turcica, posing diagnostic challenges due to varied presentations. We report the third documented case of an EPA arising from the third ventricle floor (3VF), who was successfully treated surgically. Case presentation: A 70-year-old male presented with visual impairment. Visual field tests addressed compressive optic neuropathy. Imaging revealed a well-defined mass arising from 3VF compressing the optic chiasm, confirmed as a nonfunctional EPA through histopathological and hormonal analyses. The patient underwent a lateral subfrontal translamina terminalis approach for tumor resection, ensuring maximal preservation of adjacent neurovascular structures. The procedure involved meticulous debulking of the tumor, careful preservation of the optic chiasm and hypothalamus, and watertight dural closure to minimize postoperative complications. Surgical intervention resulted in complete tumor resection without complications, leading to improved visual and endocrine function postoperatively. Conclusions: This technique emphasized minimal brain manipulation and optimal preservation of neural integrity, contributing to the patient's successful recovery following surgery. This surgical technique can be applied in similar 3VF cases, ensuring successful outcomes with minimal complications. © 2025 The Author(s)

Style	Citing Format
MLA	Sharifi G, et al.. "A Rare Case of Ectopic Pituitary Adenoma Originating From the Third Ventricle Floor: Surgical Approach and Outcomes." Interdisciplinary Neurosurgery: Advanced Techniques and Case Management, vol. 40, no. , 2025, pp. -.
APA	Sharifi G, Paraandavaji E, Naghizadeh S, Nilipour Y, Kazemi MA, Ebrahimpur M, Jafari A, Taghizadehhesary F (2025). A Rare Case of Ectopic Pituitary Adenoma Originating From the Third Ventricle Floor: Surgical Approach and Outcomes. Interdisciplinary Neurosurgery: Advanced Techniques and Case Management, 40(), -.
Chicago	Sharifi G, Paraandavaji E, Naghizadeh S, Nilipour Y, Kazemi MA, Ebrahimpur M, Jafari A, Taghizadehhesary F. "A Rare Case of Ectopic Pituitary Adenoma Originating From the Third Ventricle Floor: Surgical Approach and Outcomes." Interdisciplinary Neurosurgery: Advanced Techniques and Case Management 40, no. (2025): -.
Harvard	Sharifi G et al. (2025) 'A Rare Case of Ectopic Pituitary Adenoma Originating From the Third Ventricle Floor: Surgical Approach and Outcomes', Interdisciplinary Neurosurgery: Advanced Techniques and Case Management, 40(), pp. -.
Vancouver	Sharifi G, Paraandavaji E, Naghizadeh S, Nilipour Y, Kazemi MA, Ebrahimpur M, et al.. A Rare Case of Ectopic Pituitary Adenoma Originating From the Third Ventricle Floor: Surgical Approach and Outcomes. Interdisciplinary Neurosurgery: Advanced Techniques and Case Management. 2025;40():-.
BibTex	@article{ author = {Sharifi G and Paraandavaji E and Naghizadeh S and Nilipour Y and Kazemi MA and Ebrahimpur M and Jafari A and Taghizadehhesary F}, title = {A Rare Case of Ectopic Pituitary Adenoma Originating From the Third Ventricle Floor: Surgical Approach and Outcomes}, journal = {Interdisciplinary Neurosurgery: Advanced Techniques and Case Management}, volume = {40}, number = {}, pages = {-}, year = {2025} }
RIS	TY - JOUR AU - Sharifi G AU - Paraandavaji E AU - Naghizadeh S AU - Nilipour Y AU - Kazemi MA AU - Ebrahimpur M AU - Jafari A AU - Taghizadehhesary F TI - A Rare Case of Ectopic Pituitary Adenoma Originating From the Third Ventricle Floor: Surgical Approach and Outcomes JO - Interdisciplinary Neurosurgery: Advanced Techniques and Case Management VL - 40 IS - SP - EP - PY - 2025 ER -

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Abstract