Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Splenic Hamartoma: Immunohistochemical Profile; a Case Report Pubmed



Tavangar SM1 ; Abdollahi A2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Pathology, Tehran University of Medical Sciences, Imam Hospital Complex, Tehran, Iran

Source: Acta Medica Iranica Published:2017


Abstract

Splenic hamartoma is an unusual accidental finding with non-neoplastic feature that may be incidentally diagnosed because of its compression effect on surrounding organs. The predominant pathological feature leading diagnosis is circumscribed, un-encapsulated bulging nodules with focal fibrosis or cyst. The histopathological feature of splenic hamartoma is the positivity for CD8, and occasionally for CD31, CD34, and CD68 biomarkers on vascular wall but the cells are frequently negative for CD21. Herein, we describe a case with initial diagnosis of nephrolithiasis due to abdominal pain that was finally confirmed as splenic hamartoma by histopathological assessments and detection of CD8, CD31, CD34, and CD68 positivity. © 2017 Tehran University of Medical Sciences. All rights reserved.