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Conjugal Multiple Sclerosis in Isfahan, Iran: A Population-Based Study Publisher Pubmed



Maghzi AH1, 5 ; Etemadifar M2 ; Shaygannejad V2 ; Saadatnia M2 ; Salehi M3 ; Hassanzadeh A4
Authors
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Authors Affiliations
  1. 1. Medical School, Isfahan University of Medical Sciences, Isfahan 81744-176, Iran
  2. 2. Department of Neurology, Medical School, Isfahan University of Medical Sciences, Isfahan 81744, Iran
  3. 3. Department of Genetics and Molecular Biology, Medical School, Isfahan University of Medical Sciences, Isfahan 81744-176, Iran
  4. 4. Department of Epidemiology and Biostatistics, Medical School, Isfahan University of Medical Sciences, Isfahan 814450-4500, Iran
  5. 5. Isfahan MS Society, Isfahan 81588-44799, Bozorgmehr Ave., Iran

Source: Multiple Sclerosis Published:2007


Abstract

Conjugal multiple sclerosis (MS) is a rare form of MS in which both spouses are affected, and at least one is affected after marriage. Among 1606 definite MS patients, 1076 were in marital relationship, among whom we identified six conjugal pairs, giving the conjugal rate of 0.5%. This rate is 12.5 times higher than the estimated risk of MS for the general population (0.04%). The observed conjugal rate suggests an increased risk of developing MS for MS patients' spouses, this could be due to transmission or, more likely, to the same environmental factors shared in adult life. © 2007 SAGE Publications.
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