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An Intracranial Extramedullary Hematopoiesis in a 34-Year-Old Man With Beta Thalassemia: A Case Report Publisher



Tabesh H1 ; Shekarchizadeh A2 ; Mahzouni P3 ; Mokhtari M4 ; Abrishamkar S1 ; Abbasi Fard S1
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Authors Affiliations
  1. 1. Department of Neurosurgery, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Neurosurgery, Kashani Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Pathology, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Department of Pathology, Kashani Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Medical Case Reports Published:2011


Abstract

Introduction. Extramedullary hematopoiesis occurs in approximately 15% of cases of thalassemia. Intracranial deposits of extramedullary hematopoiesis are an extremely rare compensatory process in intermediate and severe thalassemia. Case presentation. We present an unusual case of an intracranial extramedullary hematopoiesis with a choroid plexus origin in a 34-year-old Caucasian man with beta thalassemia intermedia, who presented with the complaints of chronic headache and rapid progressive visual loss. Conclusion: An intracranial extramedullary hematopoiesis, although extremely rare, should be considered as a potential ancillary diagnosis in any thalassemic patient and therefore appropriate studies should be performed to investigate the probable intracranial ectopic marrow before any surgical intervention. © 2011 Tabesh et al; licensee BioMed Central Ltd.
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