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The Effect of the Ketogenic Diet on the Growth and Biochemical Parameters of the Children With Resistant Epilepsy.



Mohammadreza A1 ; Mohammadreza G2 ; Farhad M3 ; Karimzadeh P4 ; Mohammadreza S4 ; Hassan TS4
Authors
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Authors Affiliations
  1. 1. Depatment of Pediatric Endocrinology, Pediatric Neurology Research Center, Shahid Beheshti University of Medical Sciences(SBMU), Tehran, Iran
  2. 2. Depatment of Pediatric Neurology, Pediatric Neurology Research Center, Isfahan Medical University, Isfahan, Iran
  3. 3. Depatment of Pediatric Neurology, Pediatric Neurology Research Center, Shahid Beheshti University of Medical Sciences(SBMU), Tehran, Iran
  4. 4. Shahid Beheshti University of Medical Sciences(SBMU), Tehran, Iran

Source: Iranian Journal of Child Neurology Published:2010

Abstract

Objective The aim of this study was to evaluate the effect of the ketogenic diet on the growth parameters of the children with resistant epilepsy. Materials & Methods A total of 36 children with resistant epilepsy who were 2 to 7 year old were put on the ketogenic diet. Their growth and biochemical parameters were studied at the beginning of the study and after 3 months. Results Weight decreased in all patients. Serum levels of hemoglobin, calcium, and blood sugar decreased significantly but remained in the normal range. Creatinine did not change, but BUN showed a significant increase. Conclusion We can lower the complications of ketogenic diets by using more unsaturated fat, more water, and more minerals.
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1. Efficacy of the Ketogenic Diet As a Therapy for Intractable Epilepsy in Children, Iranian Journal of Child Neurology (2010)
2. Effects of a Formula-Based Ketogenic Diet on Refractory Epilepsy in 1 to 3 Year-Old Patients Under Classic Ketogenic Diet, Iranian Journal of Child Neurology (2019)
3. The Effect of Ketogenic Diet on Body Composition and Anthropometric Measures: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Critical Reviews in Food Science and Nutrition (2022)
4. Efficacy of Levetiracetam in Children With Refractory Epilepsy As an Add-On Trial, Epilepsy Research (2010)
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Mohammadreza Ghazavi (1)