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A Qualitative Survey of Five Antibiotics in a Water Treatment Plant in Central Plateau of Iran Publisher Pubmed



Heidari M1 ; Kazemipour M2 ; Bina B1 ; Ebrahimi A1 ; Ansari M3 ; Ghasemian M1 ; Amin MM1
Authors
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Authors Affiliations
  1. 1. Environment Research Center, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran
  2. 2. Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran
  3. 3. Pharmaceutics Research Center, Faculty of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran

Source: Journal of Environmental and Public Health Published:2013


Abstract

Introduction. This study aimed to survey a total of five common human and veterinary antibiotics based on SPE-LC-MS-MS technology in a water treatment plant at central plateau of Iran. Also two sampling techniques, passive and grab samplings, were compared in the detection of selected antibiotics. Materials and Methods. In January to March 2012, grab and passive samples were taken from the influent and effluent of a water treatment plant. The samples were prepared using solid-phase extraction (SPE), and extracts were analyzed by liquid chromatography tandem mass spectrometry (LC-MS-MS). Results. The results showed that enrofloxacin, oxytetracycline, and tylosin were not detected in none of the samples. However, ampicillin was detected in the grab and passive samples taken from the influent (source water) of the plant, and ciprofloxacin was detected in passive samples taken from the influent and effluent (finished water) of the plant. Conclusion. The results imply that passive sampling is a better approach than grab sampling for the investigation of antibiotics in aquatic environments. The presence of ampicillin and ciprofloxacin in source water and finished water of the water treatment plant may lead to potential emergence of resistant bacteria that should be considered in future studies. © 2013 Mohsen Heidari et al.
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