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The Antimicrobial Activity of Ferula Gummosa on Bacterial Strains Isolated From Patients With Gastroenteritis



Fariba F1, 2 ; Sara RR1 ; Latif G1 ; Bita P1 ; Hajieh GS3
Authors
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Authors Affiliations
  1. 1. Infectious Disease and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Department of microbiology, Shahid Beheshti University of medical sciences, Tehran, Iran
  3. 3. Department of microbiology, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Iranian Journal of Clinical Infectious Diseases Published:2011

Abstract

Purpose: Ferula gummosa grows as a native plant in different parts of Iran and has been used for treatment of some infections such as UTI since ancient times. Present study is planned to show the antibacterial effect of this herb on bacteria isolated from infectious diarrhea. Material and Methods: Extracts of the plant were achieved, using maceration method. The concentration of 0.2gr/ml was used against pathogenic bacteria causing gastroenteritis; isolated from patients admitted to Shahid Beheshti University of Medical Sciences Hospitals and MIC (minimum inhibitory concentration) of the extract was determined too. Results: The highest value of MIC was due to Proteus mirabilis and Escherichia coli and Klebsiella Pnemonia and even Pseudomonas with 1/1024 dilution liter. Three antibiotics of tetracycline, trimethoprim and ciprofloxacin were also tested against the bacteria. The most MIC was due to 1/1000 mg/ml of ciprofloxacin and was againt Pseudomonas aeroginosa, and against Serratia marcescens with MIC dilution of 1/2.
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