Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
A Concise Review on Cancer Treatment Methods and Delivery Systems Publisher



Bidram E1 ; Esmaeili Y2 ; Ranjiburachaloo H3 ; Alzaubai N4 ; Zarrabi A5 ; Stewart A4 ; Dunstan DE3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Biosensor Research Center (BRC), Department of Biomaterials, Nanotechnology, and Tissue Engineering, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences (IUMS), Isfahan, Iran
  2. 2. Department of Biotechnology, Faculty of Advanced Sciences & Technologies, University of Isfahan, Isfahan, Iran
  3. 3. Department of Chemical and Biomolecular Engineering, University of Melbourne, Melbourne, 3010, VIC, Australia
  4. 4. Department of Pharmacology and Therapeutics, University of Melbourne, Melbourne, 3010, VIC, Australia
  5. 5. Sabanci University Nanotechnology Research and Application Center (SUNUM), Tuzla, Istanbul, 34956, Turkey

Source: Journal of Drug Delivery Science and Technology Published:2019


Abstract

The ultimate purpose of current cancer research is to develop a comprehensive treatment for cancer. Recent studies have shown an increased interest in investigating the capacity of delivery systems and pharmaceutical conjugations for cancer treatment. However, in spite of all these efforts, few attempts have been made to summarize this growing body of work. This review discusses the wide range of recently developed cancer treatment methods, highlighting the latest advances in the development of delivery technologies. This study begins with looking at traditional strategies in cancer therapy, continued by the current potential nano-carriers introducing the novel designed systems. The comprehensive deduction of various applied methods considering the clinical progress also presented. The challenges involved in those promoted cancer treatments are then discussed, to provide a clear perspective on the future of effective delivery and treatment methods. © 2019 Elsevier B.V.
Related Docs
View other Related Docs
1. Dendrimers As Nanoscale Vectors: Unlocking the Bars of Cancer Therapy, Seminars in Cancer Biology (2022)
2. Development and Optimization of Transferrin-Conjugated Nanostructured Lipid Carriers for Brain Delivery of Paclitaxel Using Box–Behnken Design, Pharmaceutical Development and Technology (2017)
3. Polymeric Nanoparticles in Cancer Chemotherapy: A Narrative Review, Iranian Journal of Public Health (2022)
4. Advanced Nanosystems for Cancer Therapeutics: A Review, ACS Applied Nano Materials (2023)
5. Nanoparticles for Targeted Delivery of Therapeutics and Small Interfering Rnas in Hepatocellular Carcinoma, World Journal of Gastroenterology (2015)
6. Antitumor Activity of Raloxifene-Targeted Poly(Styrene Maleic Acid)-Poly (Amide-Ether-Ester-Imide) Co-Polymeric Nanomicelles Loaded With Docetaxel in Breast Cancer-Bearing Mice, Investigational New Drugs (2018)
7. Targeted Nanostructured Lipid Carrier for Brain Delivery of Artemisinin: Design, Preparation, Characterization, Optimization and Cell Toxicity, Journal of Pharmacy and Pharmaceutical Sciences (2018)
8. A Review on Application of Novel Solid Nanostructures in Drug Delivery, Journal of Nano Research (2018)
Experts (# of related papers)
View all Related Experts
Jaleh Varshosaz (71)
Farshid Hassanzadeh (31)
Other Related Docs
9. Lipoprotein Like Nanoparticles Used in Drug and Gene Delivery, Current Pharmaceutical Design (2016)
10. Evaluation of Lipid Nanocarriers in the Form of Sln and Their Application in Drug Delivery, Nanochemistry Research (2023)
11. Recent Progress in Cancer Immunotherapy: Application of Nano-Therapeutic Systems, Journal of Drug Delivery Science and Technology (2024)
12. Transferrin-Targeted Poly(Butylene Adipate)/Terephthalate Nanoparticles for Targeted Delivery of 5-Fluorouracil in Ht29 Colorectal Cancer Cell Line, Journal of Bioactive and Compatible Polymers (2017)
13. Bioavailability, Biodistribution, and Toxicity of Fluorescent Metal Nanoclusters, Luminescent Metal Nanoclusters: Synthesis, Characterization, and Applications (2022)
14. Folic Acid Targeted Polymeric Micelles Based on Tocopherol Succinate-Pulluan As an Effective Carrier for Epirubicin: Preparation, Characterization and In-Vitro Cytotoxicity Assessment, Current Drug Delivery (2018)
15. Thermosensitive Folic Acid-Targeted Poly (Ethylene-Co-Vinyl Alcohol) Hemisuccinate Polymeric Nanoparticles for Delivery of Epirubicin to Breast Cancer Cells, Iranian Polymer Journal (English Edition) (2016)
16. Intraocular Drug Delivery Systems for Diabetic Retinopathy: Current and Future Prospective, BioImpacts (2025)
17. Lomustine Loaded Superparamagnetic Iron Oxide Nanoparticles Conjugated With Folic Acid for Treatment of Glioblastoma Multiforma (Gbm), Iranian Journal of Pharmaceutical Research (2020)
18. Recent Advances in Nanomaterials Development for Nanomedicine and Cancer, ACS Applied Bio Materials (2021)
19. Luteinizing Hormone-Releasing Hormone Targeted Poly(Methyl Vinyl Ether Maleic Acid) Nanoparticles for Doxorubicin Delivery to Mcf-7 Breast Cancer Cells, IET Nanobiotechnology (2016)
20. Carbon-Based Nanomaterials for Targeted Cancer Nanotherapy: Recent Trends and Future Prospects, Journal of Drug Targeting (2021)
21. Nanosponges for Drug Delivery and Cancer Therapy: Recent Advances, Nanomaterials (2022)
22. Sirna Delivery Improvement by Co-Formulation of Different Modified Polymers in Erythroleukemic Cell Line K562, Iranian Journal of Basic Medical Sciences (2013)
23. Plga-Peg-Ra-Based Polymeric Micelles for Tumor Targeted Delivery of Irinotecan, Pharmaceutical Development and Technology (2018)
24. Functionalized Graphene Oxide/Fe3o4 Nanocomposite: A Biocompatible and Robust Nanocarrier for Targeted Delivery and Release of Anticancer Agents, Journal of Biotechnology (2021)
25. In Vitro and in Vivo Evaluation of Novel Dtx-Loaded Multifunctional Heparin-Based Polymeric Micelles Targeting Folate Receptors and Endosomes, Recent Patents on Anti-Cancer Drug Discovery (2020)
26. Synthesis of Some New Porphyrins and Their Metalloderivatives As Potential Sensitizers in Photo-Dynamic Therapy, Research in Pharmaceutical Sciences (2015)
27. Immunotherapy a New Hope for Cancer Treatment: A Review, Pakistan Journal of Biological Sciences (2018)
28. Natural Resources for Sustainable Synthesis of Nanomaterials With Anticancer Applications: A Move Toward Green Nanomedicine, Environmental Research (2023)
29. Trastuzumab and Folic Acid Functionalized Gold Nanoclusters As a Dual-Targeted Radiosensitizer for Megavoltage Radiation Therapy of Human Breast Cancer, European Journal of Pharmaceutical Sciences (2020)
30. Lipid Nanocapsules for Imatinib Delivery: Design, Optimization and Evaluation of Anticancer Activity Against Melanoma Cell Line, Iranian Journal of Pharmaceutical Research (2019)
31. Could Fa-Pg-Spions Act As a Hyperthermia Sensitizing Agent? an in Vitro Study, Journal of Thermal Biology (2018)
32. Therapeutic Monoclonal Antibodies for Non-Hodgkin Lymphoma: A Literature Review, Current Cancer Therapy Reviews (2024)
33. Genetically Engineered Viral Vectors and Organic-Based Non-Viral Nanocarriers for Drug Delivery Applications, Advanced Healthcare Materials (2022)
34. Recent Advancements to Engineer Mesenchymal Stem Cells and Their Extracellular Vesicles for Targeting and Destroying Tumors, Progress in Biophysics and Molecular Biology (2023)
35. Mxenes in Photomedicine: Advances and Prospects, Chemical Communications (2022)
36. Mesoporous Silica@Chitosan@Gold Nanoparticles As “On/Off” Optical Biosensor and Ph-Sensitive Theranostic Platform Against Cancer, International Journal of Biological Macromolecules (2022)
37. Feasibility of Haloperidol-Anchored Albumin Nanoparticles Loaded With Doxorubicin As Dry Powder Inhaler for Pulmonary Delivery, Pharmaceutical Development and Technology (2015)
38. Ultrasound Responsive Gd-Dota/Doxorubicin-Loaded Nanodroplet As a Theranostic Agent for Magnetic Resonance Image-Guided Controlled Release Drug Delivery of Melanoma Cancer, European Journal of Pharmaceutical Sciences (2022)
39. Biotin-Encoded Pullulan-Retinoic Acid Engineered Nanomicelles: Preparation, Optimization and in Vitro Cytotoxicity Assessment in Mcf-7 Cells, Indian Journal of Pharmaceutical Sciences (2016)
40. Hollow Mesoporous Prussian Blue Nanoparticles for in Vivo Synergistic Chemo-Photothermal Cancer Therapy and Dual-Mode Magnetic Resonance/Fluorescence Imaging, ACS Applied Nano Materials (2024)
41. Ciprofloxacin Loaded Alginate/Chitosan and Solid Lipid Nanoparticles, Preparation, and Characterization, Journal of Dispersion Science and Technology (2012)
42. Boron Phenyl Alanine Targeted Chitosan–Pnipaam Core–Shell Thermo-Responsive Nanoparticles: Boosting Drug Delivery to Glioblastoma in Bnct, Drug Development and Industrial Pharmacy (2021)
43. Multifunctional and Stimuli-Responsive Liposomes in Hepatocellular Carcinoma Diagnosis and Therapy, Translational Oncology (2024)
44. Cadmium Telluride Quantum Dots Induce Apoptosis in Human Breast Cancer Cell Lines, Toxicology and Industrial Health (2018)
45. Genetically Engineered Mesenchymal Stem Cells: Targeted Delivery of Immunomodulatory Agents for Tumor Eradication, Cancer Gene Therapy (2020)
46. Camouflaged Liposomes by 11A4-Nanobody for Co-Delivery of Cisplatin and Nitroxoline in Breast Cancer Tumors: An in Vitro/In Vivo Study, Journal of Drug Delivery Science and Technology (2022)
47. Design, Synthesis, and Comparison of Pla-Peg-Pla and Peg-Pla-Peg Copolymers for Curcumin Delivery to Cancer Cells, Polymers (2023)
48. Viral Nanoparticles-Mediated Delivery of Therapeutic Cargo, Advanced Therapeutics (2023)
49. Anticancer Nano-Delivery Systems Based on Bovine Serum Albumin Nanoparticles: A Critical Review, International Journal of Biological Macromolecules (2021)
50. Docetaxel-Loaded Nanostructured Lipid Carriers Functionalized With Trastuzumab (Herceptin) for Her2-Positive Breast Cancer Cells, Journal of Liposome Research (2018)