Liver Transplantation Status in Iran: A Multi-Center Report on the Main Transplant Indicators and Survival Rates Pubmed



Malekhosseini SA¹ ; Jafarian A² ; Nikeghbalian S¹ ; Poustchi H³ ; Lankarani KB¹ ; Toosi MN² ; Salahi H¹ ; Dehghani SM¹ ; Eshraghian A¹ ; Sharafkhah M³ ; Eghtesad S³ ; Motamedgorji N³ ; Kazemi K¹ ; Salimi J² Show All Authors Show Affiliations
Source: Archives of Iranian Medicine Published:2018

Abstract

Background: Iran’s experience with liver transplantation (LT) began more than two decades ago. The purpose of this article is to present the status of LT in Iran, review specific characteristics of the programs, their outcomes, and their growth to become one of the largest LT programs in the world. Methods: A questionnaire, asking for data on the number of transplants performed and specifics of the recipients and type of donors with focus on indications and outcomes was sent to LT programs. Results: During a period of 23 years, 4,485 LTs were performed at 6 centers in the country. Of these, 4106 were from deceased donors and 379 were from living donors. There were 3553 adults and 932 pediatric recipients. Hepatitis B and biliary atresia were the most common etiologies in adult and pediatric patients, respectively. Overall survival rates at 1, 5, and 10 years were 85%, 77%, and 71% for adults and 76%, 67% and 56% for pediatric patients, respectively. Conclusion: Approval of the brain death law in Iran and coordinated efforts by the transplant centers to build comprehensive LT programs has resulted in the ability to procure more than 700 deceased donors per year with acceptable long-term survival. © 2018 The Author(s).