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Antibiotic Resistance Pattern of Helicobacter Pylori Strains Isolated From Patients in Isfahan, Iran Publisher



Sadeghi H1 ; Narimani T2 ; Tabesh E3 ; Shafiee F4 ; Soltani R5, 6
Authors
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Authors Affiliations
  1. 1. Students Research Committee, School Of Pharmacy And Pharmaceutical Sciences, Isfahan University Of Medical Sciences, Isfahan, Iran
  2. 2. Department Of Microbiology, School Of Medicine, Isfahan University Of Medical Sciences, Isfahan, Iran
  3. 3. Gastroenterology And Hepatology Research Center, Isfahan University Of Medical Sciences, Isfahan, Iran
  4. 4. Department Of Pharmaceutical Biotechnology, School Of Pharmacy And Pharmaceutical Sciences, Isfahan University Of Medical Sciences, Isfahan, Iran
  5. 5. Department Of Clinical Pharmacy And Pharmacy Practice, School Of Pharmacy And Pharmaceutical Sciences, Isfahan University Of Medical Sciences, Iran
  6. 6. Infectious Diseases And Tropical Medicine Research Center, Isfahan University Of Medical Sciences, Isfahan, Iran

Source: Journal of Research in Medical Sciences Published:2022


Abstract

Background: The objective of this study was to evaluate the antibiotic resistance pattern of Helicobacter pylori strains isolated from patients in Isfahan province. Materials and Methods: Gastric antrum biopsy specimens of patients undergoing endoscopy were cultured. The samples with the growth of H. pylori underwent antibiotic susceptibility test by disk diffusion method. Reaults: Of 96 samples, 50 samples (53%) were positive for H. pylori. The rates of antibiotic resistance were as follows: amoxicillin, 6%; azithromycin, 20%; furazolidone, 22%; levofloxacin, 16%; metronidazole, 20%; rifampin, 12%; and tetracycline, 22%. Conclusion: H. pylori strains in our area have high rates of resistance to azithromycin, levofloxacin, metronidazole, tetracycline, and furazolidone. © 2022 Journal of Research in Medical Sciences Published by Wolters Kluwer-Medknow.
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