Giant High-Grade Immature Teratoma of the Central Nervous System (Cns) in an Infant: A Case Report Publisher Pubmed



Riazi A¹ ; Larry M¹ ; Mokhtari A¹ ; Abdali H² ; Asfia M³ ; Bagherieh S² Show Affiliations
Source: American Journal of Case Reports Published:2021

Abstract

Patient: Male, 16-day-old Final Diagnosis: High-grade immature CNS teratoma Symptoms: Brain mass • vision changes Medication: — Clinical Procedure: Surgical removal Specialty: Neurosurgery Objective: Background: Case Report: Conclusions: Congenital defects/diseases The central nervous system (CNS) is a rare point of origin for mature or immature teratomas. However, immature teratomas are extremely rare. CNS teratomas have been known for poor patient prognosis and recovery and also reduce survival. However, chemoradiotherapy has been reported to increase patient survival. This study presents a rare giant immature teratoma invading a newborn infant’s brain tissue and CNS. The tumor was surgically removed, and in a further 1-year follow-up, it did not need chemotherapy or radiotherapy according to alpha-fetoprotein (aFP) level and other serum markers. The teratoma had affected multiple loci of his brain’s left hemisphere, including parietal, frontal, temporal, and occipital lobes. A teratoma was diag-nosed lateral to the midline, which is not common in CNS teratomas, as they mainly occur in or near the mid-line. The tumor was excised completely. The patient was followed up for 1 year, and no further recurrence was observed. Early diagnosis and treatment of immature teratomas are essential in patient prognosis. Chemotherapy is not always needed, but complete surgical removal and patient follow-up are always a necessity. In addition, ade-quate follow-up of these patients is critical to evaluate their further treatment plan and recurrence risk. © Am J Case Rep.