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Review of Electrochemical and Optical Biosensors for Testosterone Measurement Publisher Pubmed



Nikkhah M1 ; Karami S2 ; Khatami SH3 ; Taherianganeh M4 ; Savardashtaki A5 ; Mahmoodzadeh A6 ; Shabaninejad Z1 ; Vakili O7 ; Mousavi P8 ; Ghanizadeh Gerayeli F9 ; Behrouj H10 ; Ghasemi H11 ; Movahedpour A10
Authors
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Authors Affiliations
  1. 1. Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran
  2. 2. Department of Chemistry, Shiraz University, Shiraz, Iran
  3. 3. Department of Clinical Biochemistry, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Cellular and Molecular Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences, Urmia, Iran
  5. 5. Department of Medical Biotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran
  6. 6. Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran
  7. 7. Department of Clinical Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
  8. 8. Department of Medical Genetics, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
  9. 9. Department of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran
  10. 10. Behbahan Faculty of Medical Sciences, Behbahan, Iran
  11. 11. Abadan University of Medical Sciences, Abadan, Iran

Source: Biotechnology and Applied Biochemistry Published:2023


Abstract

Testosterone is an anabolic steroid and a major sex hormone in males. It plays vital roles, including developing the testis, penis, and prostate, increasing muscle and bone, and sperm production. In both men and women, testosterone levels should be in normal ranges. Besides, testosterone and its analogs are major global contributors to doping in sport. Due to the importance of testosterone testing, novel, accurate biosensors have been developed. This review summarizes the various methods for testosterone measurement. Also, recent optical and electrochemical approaches for the detection of testosterone and its analogs have been discussed. © 2022 International Union of Biochemistry and Molecular Biology, Inc.
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