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Anxiety and Salivary Level of Alpha-Amylase in Patients With Geographic Tongue: A Case Control Study Publisher



Tavangar A1 ; Saberi Z2 ; Rahimi M3 ; Pakravan F4
Authors
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Authors Affiliations
  1. 1. Dental Materials Research Center, Department of Oral Medicine, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Dental Research Center, Department of Oral Medicine, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. School of Dentistry, Isfahan University of Medical Science, Isfahan, Iran
  4. 4. Dental Implant Research Cente, Department of Oral Medicine, Dental Research Institute, sfahan University of Medical Sciences, Isfahan, Iran

Source: Open Dentistry Journal Published:2019


Abstract

Background: Geographic tongue is a common benign condition involving the tongue with an unknown etiology. Objective: This study aimed to measure the salivary level of alpha-amylase as well as the level of anxiety of patients with geographic tongue. Methods: This case-control study was performed on 180 subjects including 89 patients with geographic tongue and 91 controls. The subjects were requested to fill out the Spielberger’s State-Trait Anxiety Inventory (STAI-S, STAI-T). Unstimulated saliva samples were collected by the spitting method to assess the salivary level of alpha-amylase. Data were analyzed using SPSS version 23, t-test and Pearson’s test (α=0.05). Results: The mean salivary level of alpha-amylase and the mean scores of state and trait anxiety in geographic tongue patients were higher than those of healthy controls. But these differences did not reach statistical significance (P>0.05). Conclusion: Anxiety may be an influential factor in the occurrence of geographic tongue. Salivary level of alpha-amylase cannot serve as a specific biomarker for assessment of geographic tongue. © 2019 Tavangar et al.