Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Antioxidative Stress Potential of Cinnamomum Zeylanicum in Humans: A Comparative Cross-Sectional Clinical Study Publisher



Ranjbar A1 ; Ghasmeinezhad S1 ; Zamani H1 ; Malekirad AA2 ; Baiaty A3 ; Mohammadirad A4 ; Abdollahi M5
Authors
Show Affiliations
Authors Affiliations
  1. 1. Arak University of Medical Sciences, Faculty of Paramedical Science, Arak, Iran
  2. 2. Esfahan Payam Noor University of Sciences, Esfahan, Iran
  3. 3. Isfahan University of Medical Sciences, Faculty of Nursing and Midwifery Sciences, Isfahan, Iran
  4. 4. Tehran University of Medical Sciences, Faculty of Pharmacy, Pharmaceutical Sciences Research Center, Tehran 14155 6451, Iran
  5. 5. Tehran University of Medical Sciences, Laboratory of Toxicology, Department of Pharmacology and Toxicology, Tehran 14155 6451, Iran

Source: Therapy Published:2006


Abstract

Background: Cinnamomum zeylanicum is an important spice and aromatic crop used in folk medicine. Cinnamon is usually regarded as the bark of the C. zeylanicum tree. Objective: The objective of this study was to determine the antioxidative stress capacity of cinnamon in humans when administered in a regular and controlled manner. Methods: A total of 54 normal subjects were divided into three groups, receiving water, regular tea or cinnamon tea for 2 weeks. Blood samples were obtained before and after treatment and analyzed for lipid peroxidation levels, total antioxidant power and total thiol groups by standard methods. Results: The results indicated increased total antioxidant power and total thiols but a decrease in lipid peroxidation levels in individuals who received regular or cinnamon tea compared with controls. The extent of increase in total antioxidant power and decrease in lipid peroxidation levels were more evident in individuals who received cinnamon tea compared with those who received regular tea. Conclusion: Cinnamon has a marked antioxidant potential and may be beneficial in alleviating the complications of many illnesses related to oxidative stress in humans. © 2006 Future Drugs Ltd.
Related Docs
View other Related Docs
1. On the Benefit of Cinnamomum Zeylanicum for Radiology Unit Staff, Journal of Medical Sciences (2008)
2. Cinnamon and Chronic Diseases, Advances in Experimental Medicine and Biology (2016)
3. Preventive Effect of Cinnamon Essential Oil on Lipid Oxidation of Vegetable Oil, ARYA Atherosclerosis (2013)
4. What Is the Impact of Cinnamon Supplementation on Blood Pressure? a Systematic Review and Meta-Analysis, Endocrine, Metabolic and Immune Disorders - Drug Targets (2021)
5. The Effect of Cinnamon Supplementation on Blood Pressure in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Clinical Nutrition ESPEN (2020)
6. Anti-Hypertensive Effects of Cinnamon Supplementation in Adults: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials, Critical Reviews in Food Science and Nutrition (2020)
7. Effects of Cinnamon Oil and Its Main Constituents, Cinnamic Acid and Cinnamaldehyde, on 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Neurodegeneration in Pc-12 Cells; [Efectos Del Aceite De Canela Y Sus Principales Componentes, Acido Cinamico Y Cinamaldehido En La Neurodegeneracion Inducida Por 1-Metil-4-Fenil-1,2,3,6-Tetrahidropiridina En Celulas Pc 12], Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas (2023)
8. The Efficacy of Sour Tea (Hibiscus Sabdariffa L.) on Selected Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis of Randomized Clinical Trials, Phytotherapy Research (2020)
Experts (# of related papers)
View all Related Experts
Sedigheh Asgary (10)
Gholamreza Askari (7)
Other Related Docs
9. Effects of Green Tea Consumption on the Biochemical, Inflammatory and Antioxidant Parameters in Patients With Coronary Artery Disease, Journal of Knowledge and Health in Basic Medical Sciences (2018)
10. In Vitro Antioxidant Effects of Different Extracts Obtained From the Leaves and Seeds of Allium Ampeloprasum Subsp. Persicum, Journal of HerbMed Pharmacology (2019)
11. The Effect of Cocoa Consumption on Markers of Oxidative Stress: A Systematic Review and Meta-Analysis of Interventional Studies, Complementary Therapies in Medicine (2020)
12. The Effects of Green Tea Supplementation on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis, Frontiers in Nutrition (2023)
13. The Effects of Garlic Supplementation on Oxidative Stress Markers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Complementary Therapies in Medicine (2020)
14. Antioxidant Effect of Turmeric and Saffron on the Oxidation of Hepatocytes, Ldl and Non-Enzymatic Glycation of Hemoglobin, Journal of Medicinal Plants (2005)
15. The Effects of L-Arginine on Serum Lipid Levels in Hypercholesterolemic Rabbits and Its in Vitro Antioxidant Activity, Journal of Isfahan Medical School (2007)
16. Is Consumption of Pomegranate Supplementation Effective on Oxidative Stress Biomarkers Including Mda, Ox-Ldl, Pox 1, Gpx, Tac, and Tbras? a Systematic Review and Meta-Analysis of Randomized Controlled Trials, Current Problems in Cardiology (2023)
17. Effects of Ferulago Angulata Extract on Serum Lipids and Lipid Peroxidation, Evidence-based Complementary and Alternative Medicine (2014)
18. Preventive and Curative Effect of Garlic on Nephrotoxic Effect of Gentamicin in Rat, Journal of Babol University of Medical Sciences (2014)
19. A Randomized, Double-Blind, Placebo-Controlled Clinical Trial, Evaluating the Garlic Supplement Effects on Some Serum Biomarkers of Oxidative Stress, and Quality of Life in Women With Rheumatoid Arthritis, International Journal of Clinical Practice (2020)
20. Cinnamon: A Promising Natural Product Against Covid-19, Advances in Experimental Medicine and Biology (2021)
21. The Effect of Conjugated Linoleic Acid Supplementation on Oxidative Stress Markers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Clinical Nutrition ESPEN (2022)
22. Physicochemical Characterization, Standardization and in Vitro Determination of Radical Scavenging Activity of Zereshke-Saghir, a Traditional Preparation, and Its Ingredients, Journal of Young Pharmacists (2017)
23. Cytoprotective Effect of Hydroalcoholic Extract of Pinus Eldarica Bark Against H2o2-Induced Oxidative Stress in Human Endothelial Cells, Iranian Biomedical Journal (2016)
24. The Effects of L-Carnitine Supplementation on Inflammation, Oxidative Stress, and Clinical Outcomes in Critically Ill Patients With Sepsis: A Randomized, Double-Blind, Controlled Trial, Nutrition Journal (2024)
25. Cardiovascular Effects of Cydonia Oblonga Miller (Quince), Evidence-based Complementary and Alternative Medicine (2022)
26. Systematic Review and Meta-Analysis of Oxidative Stress and Antioxidant Markers in Recurrent Aphthous Stomatitis, BMC Oral Health (2023)
27. The Therapeutic Impact of Garlic (Allium Sativum) on Oxidative Stress Markers Among Polycystic Ovary Syndrome Patients: A Randomized, Double-Blinded Clinical Trial, International Journal of Preventive Medicine (2023)
28. Essential Oil Composition, Bioactive Compounds, and Antioxidant Activities in Iberis Amara L., Natural Product Communications (2019)
29. Cinnamon Supplementation Improves Blood Pressure in Type 2 Diabetic Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Clinical Diabetology (2020)
30. Investigation of Antioxidant and Anti-Glycation Properties of Essential Oils From Fruits and Branchlets of Juniperus Oblonga, Revista Brasileira de Farmacognosia (2012)
31. Anxiolytic Effects of Lippia Citriodora in a Mouce Model of Anxiety, Research in Pharmaceutical Sciences (2018)
32. The Effects of Wheat Germ Supplementation on Metabolic Profile in Patients With Type 2 Diabetes Mellitus: A Randomized, Double-Blind, Placebo-Controlled Trial, Phytotherapy Research (2020)
33. Comparison of Plasma Lipid Peroxidants, Glycosilated Hemoglobin, Conjugated Dienes and Cpr Level in Smokers and Non-Smokers Men, Journal of Isfahan Medical School (2009)
34. Clinical Effectiveness of Zinc Supplementation on the Biomarkers of Oxidative Stress: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Pharmacological Research (2020)
35. Rosemary and Its Protective Potencies Against Covid-19 and Other Cytokine Storm Associated Infections: A Molecular Review, Mediterranean Journal of Nutrition and Metabolism (2021)
36. The Effect of Alpha-Lipoic Acid on Inflammatory Mediators: A Systematic Review and Meta-Analysis on Randomized Clinical Trials, European Journal of Pharmacology (2019)
37. Antioxidant and Anti-Hyperlipidemic Effects of Bark Extract of Pinus Eldarica in Dexamethasone-Induced Dyslipidemic Rats, Journal of Advances in Medical and Biomedical Research (2019)
38. Antioxidant Effect of Ziziphus Vulgaris, Portulaca Oleracea, Berberisintegerima and Gundelia Tournefortti on Lipid Peroxidation, Hb Glycosylation and Red Blood Cell Hemolysis, Journal of Medicinal Plants (2011)
39. Effect of Green Tea on Plasma Leptin and Ghrelin Levels: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials, Nutrition (2018)
40. Evaluating Anti-Inflammatory Effect of Hydroalcoholic Extracts of Citrus Medica L. Pulp and Peel on Rat Model of Acute Colitis, Research Journal of Pharmacognosy (2023)
41. Preventive Effect of Cichorium Intybus L. Two Extracts on Cerulein-Induced Acute Pancreatitis in Mice, International Journal of Preventive Medicine (2012)
42. Hepatoprotective Effects of Iranian Hypericum Scabrum Essential Oils Against Oxidative Stress Induced by Acetaminophen in Rats, Brazilian Archives of Biology and Technology (2014)
43. Cardiovascular Protective Effects of Cinnamic Acid As a Natural Phenolic Acid: A Review, Archives of Physiology and Biochemistry (2025)
44. Effect of Herbal Antioxidant-Rich Formula on Improvement of Antioxidant Defense System and Heat Shock Protein-70 Expression in Recreational Female Athletes: A Randomized Controlled Trial, Journal of Research in Medical Sciences (2019)
45. Dietary Antioxidant Index and the Risk of Recurrent Aphthous Stomatitis, International Dental Journal (2024)
46. Are Antioxidants Helpful for Disease Prevention?, Research in Pharmaceutical Sciences (2010)
47. Dietary and Biochemical Characteristics Associated With Normal-Weight Obesity, International Journal for Vitamin and Nutrition Research (2019)
48. Evaluation of Fibrinolytic and Antioxidant Effects of Allium Affine Hydroalcoholic Extract, Research in Pharmaceutical Sciences (2017)
49. Effects of Cinnamon, Cardamom, Saffron, and Ginger Consumption on Markers of Glycemic Control, Lipid Profile, Oxidative Stress, and Inflammation in Type 2 Diabetes Patients, The review of diabetic studies : RDS (2014)
50. Antioxidant Effects of Methanol Extract of Dracocephalum Kotschyi in Acetic Acid Induced Rat Colitis Model, Journal of Advances in Medical and Biomedical Research (2022)