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Long-Term Pulmonary Functional Status Following Coronary Artery Bypass Grafting Surgery



Rouhiboroujeni H1 ; Rouhiboroujeni H1 ; Rouhiboroujeni P3 ; Sedehi M4
Authors
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Authors Affiliations
  1. 1. Clinical Biochemistry Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
  2. 2. Medical plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
  3. 3. School of Pharmacy, Department of Pharmacology, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran

Source: ARYA Atherosclerosis Published:2015

Abstract

BACKGROUND: The present study aimed to describe the long-term alterations of pulmonary function and also to describe its association with post-operative pain after coronary artery bypass grafting (CABG) surgery. METHODS: In this prospective study, thirty non-smoker male patients undergoing isolated onpump CABG were consecutively included in this study. Pulmonary function measurements were performed, in a sitting position, preoperatively, a week postoperatively, and 6 months after the surgery using a Medical Graphics PF/Dx pulmonary function system. Pain was determined by using visual analog scale (VAS) pain scores with a standardized questionnaire’s. RESULTS: Regarding functional class, all patients had New York Heart Association (NYHA) Class II to III. A week after operation, a severe restrictive pulmonary impairment was revealed with a mean decrease in VC to 60.9 ± 9.2% and in forced expiratory volume in one second (FEV1) to 64.6 ± 12.2% of pre-operative values (P < 0.001). Regarding sternotomy related pain, the mean pain VAS score was preoperatively 3.3 ± 1.5 that reached to 6.2 ± 2.5 and 4.8 ± 2.2 1 week and 6 months after the operation (P < 0.001). The trend of the changes in pain score within 6 months of operation was significantly similar to the trend of the changes in some pulmonary function indices such as FEV% and RV. CONCLUSION: A significant reduction is expected in most pulmonary functional parameters following CABG despite normal pulmonary function state preoperatively. Severe pain originated from sternotomy may be an important factor related to pulmonary dysfunction following CABG. © 2015, Isfahan University of Medical Sciences(IUMS). All rights reserved.
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