Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Randomized Controlled Trial of Bilateral Intrapleural Block in Cardiac Surgery Publisher Pubmed



Mansouri M1, 3 ; Bageri K1 ; Noormohammadi E2 ; Mirmohammadsadegi M2 ; Mirdehgan A2 ; Ahangaran AG1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Cardiac Surgery, Chamran Heart Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Cardiac Anesthesiology, Chamran Heart Hospital, University of Medical Sciences, Isfahan, PO Box 8166173414, Iran

Source: Asian Cardiovascular and Thoracic Annals Published:2011


Abstract

The aim of this study was to determine the efficacy of bilateral intrapleural block with bupivacaine as a preemptive analgesic for postoperative pain in coronary artery bypass graft surgery. In a double-blind prospective clinical trial, 70 patients were randomly divided into a bupivacaine group (20 mL bupivacaine 0.25% and 0.5 mL adrenaline 1/200,000 each side) and a control group (20.5 mL normal saline each side). Evaluation of the severity of pain was performed using the visual analog scale at 12 and 24 h after entering the intensive care unit and again during chest tube removal. Pain scores at 12 and 24h after intensive care unit admission were significantly lower in the bupivacaine group. There were no sideeffects related to intrapleural block, such as pneumothorax or emphysema. In coronary artery bypass graft candidates, preemptive analgesia with bilateral intrapleural block using bupivacaine provided relatively less painful conditions during the first 24 h after surgery, but it did not improve the clinical outcome. © The Author(s) 2011.
Related Docs
View other Related Docs
1. Evaluation of the Effect of Preemptive Intravenous Paracetamol on Perioperative Pain in Coronary Artery Bypass Graft Surgery, Journal of Isfahan Medical School (2016)
2. Effectiveness of the Self-Report Pain Intensity Scale in Pain Control After Coronary Artery Bypass Surgery, Iranian Heart Journal (2022)
3. Pain Management After Thoracotomy With Dexamethasone and Bupivacaine Through a Peripleural Cather: A Randomized Controlled Trial, BMC Anesthesiology (2024)
4. The Efficacy of Preventive Parasternal Single Injection of Bupivacaine on Intubation Time, Blood Gas Parameters, Narcotic Requirement, and Pain Relief After Open Heart Surgery: A Randomize Clinical Trial Study, Journal of Research in Medical Sciences (2011)
5. Effects of Cold Application on Chest Tube Removal Pain in Heart Surgery Patients, Tanaffos (2018)
6. Comparison of Pre- Vs. Post-Incisional Caudal Bupivacaine for Postoperative Analgesia in Unilateral Pediatric Herniorrhaphy: A Double-Blind Randomized Clinical Trial, Saudi Journal of Anaesthesia (2011)
7. Effect of Pre Vs. Post Incision Inguinal Field Block on Postoperative Pain After Pediatric Herniorrhapy, a Different Approach, Journal of Research in Medical Sciences (2007)
8. The Effect of Verapamil As an Adjuvant Agent With Local Anesthetic on Sensory Block Level, Hemodynamic and Postoperative Pain, Pakistan Journal of Medical Sciences (2012)
Experts (# of related papers)
View all Related Experts
Gholamreza Khalili (12)
Hamid Hajigholam Saryazdi (11)
Other Related Docs
9. A Comparison Between Subpleural Patient-Controlled Analgesia by Bupivacaine and Intermittent Analgesia in Post-Operative Thoracotomy: A Double-Blind Randomized Clinical Trial, Journal of Research in Medical Sciences (2011)
10. Comparing the Effectiveness of Bupivacaine Administration Through Chest Tube and Intercostal Blockage in Patients With Rib Fractures, Advanced Biomedical Research (2022)
11. Effects of Intraoperative-Intrathecal Sufentanil Injection on Postoperati Pain Management After Single Level Lumbar Discectomy, Middle East Journal of Anesthesiology (2010)
12. A Comparative Study of the Effect of Adding Dexmedetomidine, Dexamethasone and Sodium Bicarbonate to Ropivacaine in Ultrasound Guided Supraclavicular Block on the Quality of the Block in Orthopedic Surgery, Archives of Anesthesiology and Critical Care (2024)
13. Comparing the Effects of Ketamine Alone and in Combination With Metoclopramide on Postoperative Pain, Journal of Isfahan Medical School (2013)
14. Comparing the Effect of Lidocaine-Prilocaine Cream and Infiltrative Lidocaine on Overall Pain Perception During Thoracentesis and Abdominocentesis: A Randomized Clinical Trial, Anesthesiology and Pain Medicine (2020)
15. Frequency of Pain Intensity and Factors Affecting It After Cesarean Section Using Spinal Anesthesia, Archives of Anesthesiology and Critical Care (2025)
16. Postoperative Analgesia After Caesarean Section: Intermittent Intramuscular Versus Subcutaneous Morphine Boluses, Acute Pain (2007)
17. Comparison of Pre-Emptive Effect of Meloxicam and Celecoxcib on Post-Operative Analgesia: A Double-Blind, Randomized Clinical Trial, Middle East Journal of Anesthesiology (2015)
18. Preventive Effects of Pudendal Nerve Block on Postoperative Pain in Anterior and Posterior Vaginal Repair, Journal of Isfahan Medical School (2012)
19. Mini-Dose Bier's Block Vs Systemic Analgesia in Distal Radius Fractures: A Promising Reduction in Emergency Department Throughput Time, Pain Management (2023)
20. Comparison of the Effects of 3 Methods of Intrathecal Bupivacaine, Bupivacaine-Fentanyl, and Bupivacaine-Fentanyl-Magnesium Sulfate on Sensory Motor Blocks and Postoperative Pain in Patients Undergoing Lumbar Disk Herniation Surgery, Journal of Neurosurgical Anesthesiology (2016)
21. Supplementing Epidural Lidocaine With Midazolam: Effect on Sensorymotor Block Level, Acta Anaesthesiologica Taiwanica (2004)
22. Comparison of Epidural and Intravenous Methods for Post-Thoracotomy Analgesia; [Confronto Tra Analgesia Epidurale E Analgesia Endovenosa Per Interventi Di Toracotomia], Acta Anaesthesiologica Italica / Anaesthesia and Intensive Care in Italy (2006)
23. The Effect of Zolpidem or Promethazine Premedication on Agitation, Sedation and Cognitive Disorders Before and After Coronary Artery Bypass Graft Surgery, Journal of Isfahan Medical School (2015)
24. Evaluation of the Distribution of Topical Bupivacaine in Epidural Anesthesia With Mri, Journal of Isfahan Medical School (2011)
25. Effects of Lidocaine on Reducing the Need for Anesthetic Drugs During Ophthalmologic Surgeries, Journal of Isfahan Medical School (2013)
26. The Comparison of Spinal Anesthesia With General Anesthesia on the Postoperative Pain Scores and Analgesic Requirements After Elective Lower Abdominal Surgery: A Randomized, Double-Blinded Study, Journal of Research in Medical Sciences (2013)
27. Comparison Between the Effect of Bupivacaine-Pethidine and Bupivacaine-Ketamine As Preemptive in Bilateral Infraorbital Nerve Block on Postoperative Pain Relief in Infants Undergoing Clef Lip Repair, a Controlled Study, Journal of Isfahan Medical School (2017)
28. Long-Term Pulmonary Functional Status Following Coronary Artery Bypass Grafting Surgery, ARYA Atherosclerosis (2015)
29. Bispectral Index Values During Spinal Anesthesia Using Hyperbaric Bupivacaine With Intrathecal or Intravenous Fentanyl for Cesarean Section, Journal of Research in Medical Sciences (2012)
30. The Effects of Intraarticular Opioids in Pain Relief After Arthroscopic Menisectomy: A Randomized Clinical Trial Study, Pakistan Journal of Medical Sciences (2012)
31. Topical Lidocaine Plus Diclofenac As a Local Anesthetic Agent in Central Venous Catheterization; a Randomized Controlled Clinical Trial, Archives of Academic Emergency Medicine (2021)
32. Comparison of Intravenous and Epidural Patient-Controlled Analgesia After Knee and Hip Arthroplasty, Journal of Isfahan Medical School (2012)
33. Postoperative Analgesic and Adverse Effects of Two Low Doses of Intrathecal Neostigmine and Its Influence on Spinal Bupivacaine Anaesthesia After Knee Arthroscopy, Acute Pain (2009)
34. Preincisional Analgesia With Subcutaneous Administration of Tramadol Reduces Postoperative Pain in Patients After Open Urologic Surgeries: A Randomized, Double-Blind, Placebo-Controlled Study, Pakistan Journal of Medical Sciences (2012)
35. Preemptive Analgesia With Ibuprofen and Acetaminophen in Pediatric Lower Abdominal Surgery, Journal of Research in Medical Sciences (2005)
36. Comparison of the Effects of Intravenous or Subcutaneous Administration of Metoclopramide on Pain and Nausea After Lower Abdominal Surgery, Journal of Isfahan Medical School (2021)
37. Comparing the Effects of Aromatherapy Massage With Passion Flower and Sesame Essential Oils on Pain Intensity Among Patients Undergoing Coronary Artery Bypass Grafting: A Randomized Parallel Trial, Nursing and Midwifery Studies (2023)
38. Analgesic Efficacy of Dexamethasone and Dexmedetomidine As an Adjuvant to Bupivacaine Infiltration in Unilateral Cleft Lip Surgery: A Randomized, Double-Blinded Study, Archives of Anesthesiology and Critical Care (2024)
39. Premedication With Oral Dextromethorphan Reduces Intra-Operative Morphine Requirement, Journal of Research in Medical Sciences (2005)
40. Effect of Intraosseous Injection Versus Inferior Alveolar Nerve Block As Primary Pulpal Anaesthesia of Mandibular Posterior Teeth With Symptomatic Irreversible Pulpitis: A Prospective Randomized Clinical Trial, Acta odontologica Scandinavica (2018)
41. Comparison the Efficacy of Pre-Emptive Oral Celecoxib With Acetaminophen in Controlling Post-Operative Pain and Nausea After Lower Limb Surgery Under General Anesthesia, Journal of Cellular and Molecular Anesthesia (2016)
42. Preincisional Administration of Intravenous or Subcutaneous Infiltration of Low-Dose Ketamine Suppresses Postoperative Pain After Appendectomy, Journal of Pain Research (2012)
43. The Effect of Intracameral Lidocaine Injection on Hemodynamic Parameters and Pain Intensity During and After Cataract Surgery Under Intravenous Sedation and Topical Anesthesia, Journal of Isfahan Medical School (2021)
44. Evaluation of Preemptive Use of Analgesia of the Skin, Before and After Lower Abdominal Surgery: A Prospective, Double-Blind, Randomized Clinical Trial, Journal of Research in Medical Sciences (2005)
45. Comparison of the Effect of Lidocaine and Its Combination With Melatonin and the Valsalva Maneuver on Etomidate Induced Injection Pain, Anaesthesia, Pain and Intensive Care (2024)
46. Effect of Preemptive and Preventive Acetaminophen on Postoperative Pain Score: A Randomized, Double-Blind Trial of Patients Undergoing Lower Extremity Surgery, Journal of Clinical Anesthesia (2013)
47. The Effects of Hyperbaric or Isobaric Bupivacaine on Bispectral Index in Spinal Anesthesia for Cesarean Section, Journal of Research in Medical Sciences (2012)
48. Effects of Adjunct Intrathecal Magnesium Sulfate to Bupivacaine for Spinal Anesthesia: A Randomized, Double-Blind Trial in Patients Undergoing Lower Extremity Surgery, Journal of Anesthesia (2011)
49. Comparison of Adding Neostigmine and Fentanyl to Bupivacaine in Caudal Analgesia Caudal in Pediatric Inguinal Herniorrhaphy, Journal of Cellular and Molecular Anesthesia (2017)
50. The Comparison of Preemptive Effects of Propofol, Remifentanil and Ketamine on Post-Operative Pain Scores and Analgesic Requirements in Elective Lower Abdominal Surgery Under General Anesthesia: A Randomized, Double-Blinded Study, Journal of Research in Medical Sciences (2013)