Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Body Weight Changes and Diabetes Mellitus Incident: A Cohort Study From the Middle East Publisher Pubmed



Salesi R1 ; Kermanialghoraishi M2 ; Sadeghi A3 ; Roohafza H4 ; Talaei M5 ; Sarrafzadegan N1 ; Sadeghi M6
Authors
Show Affiliations
Authors Affiliations
  1. 1. Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Interventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Science, Isfahan, Iran
  4. 4. Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Institute of Population Health Sciences, Barts and the London School of Medicine, Queen Mary University of London, United Kingdom
  6. 6. Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Preventive Medicine and Hygiene Published:2023


Abstract

Objective. Obesity is a known risk factor for diabetes, but the Results. During follow-ups, 261 new cases of diabetes were effect of weight changes on the incidence of diabetes is not yet recorded, with an IR of 3401.29 per 100,000 P-Y. The highest determined. This study aims to evaluate the long-term effects of number of new cases of type 2 DM belongs to participants with weight change [based on body mass index (BMI)] on the incioverweight and obesity who had minimal BMI changes (less than dence of diabetes mellitus (DM) in a middle eastern population. 5% of their baseline BMI limits; 42 and 38 new cases, respecMethod. In the Isfahan Cohort Study (ICS) 6504 adults equal or tively). Participants who were obese at baseline and had lost more greater than 35 years of age were recruited at 2001 and were than 10% or gained 5-10% of baseline BMI were in the groups followed until 2013. Absolute BMI changes (ΔBMI) were calcuwith the highest IR [360.05 - 95% CI (239.3-541.8) and 322.39 lated by subtracting the baseline BMI from the BMI measured at - 95% CI (178.5-582.1) respectively]. There was no significant follow-ups. To compare participants with different baseline BMI association between BMI changes and the incidence of DM in the easier, relative changes in BMI were quantified as the percentage participants with normal BMI, overweight, and obesity at base-of changes from baseline. DM was assessed based on standard line in cure and adjusted models. definitions. Multivariable Cox regression was used to determine Conclusions. This study showed there was no significant associathe association between ΔBMI and the incidence of diabetes. tion between diabetes mellitus incidence and BMI changes. © Copyright by Pacini Editore Srl, Pisa, Italy.
Related Docs
View other Related Docs
1. Anthropometric Indices Predicting Incident Type 2 Diabetes in an Iranian Population: The Isfahan Cohort Study, Diabetes and Metabolism (2013)
2. Patterns and Predictors of Long-Term Weight Change in Patients With Type 2 Diabetes Mellitus, Annals of Nutrition and Metabolism (2009)
3. Body Mass Index and the All-Cause Mortality Rate in Patients With Type 2 Diabetes Mellitus, Acta Diabetologica (2018)
4. Risk of Diabetes in Combined Metabolic Abnormalities and Body Mass Index Categories, Diabetes and Metabolic Syndrome: Clinical Research and Reviews (2016)
5. Determinants of Weight Change in a Longitudinal Study of Iranian Adults: Isfahan Cohort Study, Archives of Iranian Medicine (2014)
6. Factors Associated With Progression to Pre-Diabetes: A Recurrent Events Analysis, Eating and Weight Disorders (2020)
7. Metabolic Syndrome in Type 2 Diabetes Mellitus in Isfahan, Iran: Prevalence and Risk Factors, Metabolic Syndrome and Related Disorders (2007)
8. Is Responsiveness to Weight Loss Diets Affected by Family History of Diabetes?, ARYA Atherosclerosis (2014)
Experts (# of related papers)
View all Related Experts
Roya Kelishadi (72)
Nizal Sarrafzadegan (60)
Other Related Docs
9. Evaluation of the Effects of Dietary Energy Density on Anthropometric and Glycemic Indices and Lipid Profile in Women With Type 2 Diabetes Mellitus, Journal of Isfahan Medical School (2012)
10. Weight Change, Blood Pressure, Lipids and Glycemic Control Among Patients With Type 2 Diabetes, Annals of Nutrition and Metabolism (2011)
11. The Relationship Between Low-Carbohydrate Diet Score, Dietary Insulin Index and Load With Obesity in Healthy Adults, Eating and Weight Disorders (2022)
12. Comparison of Body Mass Index With Abdominal Obesity Indicators and Waist-To-Stature Ratio for Prediction of Type 2 Diabetes: The Isfahan Diabetes Prevention Study, Obesity Research and Clinical Practice (2010)
13. Risk of Diabetes According to the Metabolic Health Status and Degree of Obesity, Diabetes and Metabolic Syndrome: Clinical Research and Reviews (2017)
14. The Visceral Adiposity Index in Comparison With Easily Measurable Anthropometric Markers Did Not Improve Prediction of Diabetes, Canadian Journal of Diabetes (2016)
15. Progression to Impaired Glucose Metabolism in First-Degree Relatives of Patients With Type 2 Diabetes in Isfahan, Iran, Diabetes/Metabolism Research and Reviews (2009)
16. Determinants of Incident Metabolic Syndrome in a Middle Eastern Population: Isfahan Cohort Study, Metabolic Syndrome and Related Disorders (2017)
17. Association of Waist and Hip Circumference and Waist-Hip Ratio With Type 2 Diabetes Risk in First-Degree Relatives, Journal of Diabetes and its Complications (2016)
18. Dietary Glycemic Index and Insulin Index in Association With Incident Type 2 Diabetes Mellitus in Adults, British Journal of Nutrition (2025)
19. Glycated Hemoglobin As a Predictor for Metabolic Syndrome in an Iranian Population With Normal Glucose Tolerance, Metabolic Syndrome and Related Disorders (2012)
20. Cardiovascular Disease Risk Factors, Metabolic Syndrome and Obesity in an Iranian Population, Eastern Mediterranean Health Journal (2008)
21. Accuracy of Novel Anthropometric Indices for Assessing the Risk for Progression of Prediabetes to Diabetes; 13 Years of Results From Isfahan Cohort Study, Archives of Endocrinology and Metabolism (2024)
22. A Cross-Sectional Study on Food Patterns and Adiposity Among Individuals With Abnormal Glucose Homeostasis, Archives of Iranian Medicine (2012)
23. Weight Status of the First-Degree Relatives of Patients With Type 2 Diabetes Based on the Glucose Tolerance Test, Journal of Research in Medical Sciences (2012)
24. The Association Between Dietary Inflammatory Index With Some Cardio-Metabolic Risk Indices Among the Patients With Type 2 Diabetes From Hoveyzeh Cohort Study: A Cross-Sectional Study, BMC Endocrine Disorders (2024)
25. People With Impaired Glucose Tolerance and Impaired Fasting Glucose Are Similarly Susceptible to Cardiovascular Disease: A Study in First-Degree Relatives of Type 2 Diabetic Patients, Annals of Nutrition and Metabolism (2010)
26. Dietary Glycemic Index and Glycemic Load in Relation to General Obesity and Central Adiposity Among Adults, Clinical Nutrition (2019)
27. Dietary Insulin Index and Load and Cardiometabolic Risk Factors Among People With Obesity: A Cross-Sectional Study, BMC Endocrine Disorders (2023)
28. Comparison of Metabolic Syndrome With Glucose Measurement for Prediction of Type 2 Diabetes: The Isfahan Diabetes Prevention Study, Diabetes and Metabolic Syndrome: Clinical Research and Reviews (2009)
29. Trend Analysis, Gender-Specific Patterns, and Age Dynamics of Childhood and Adolescent Obesity: Insights From the Tehran Lipid and Glucose Study, BMC Public Health (2024)
30. The Association Between Dietary Diversity Score and Food Insecurity and Novel Cardiovascular Risk Factors in Type 2 Diabetes Mellitus Patients: A Cross-Sectional Study, Journal of Diabetes and Metabolic Disorders (2025)
31. Relationship Between Dietary Patterns and Incidence of Type 2 Diabetes, International Journal of Preventive Medicine (2019)
32. How Is Healthy Eating Index-2015 Related to Risk Factors for Cardiovascular Disease in Patients With Type 2 Diabetes, Frontiers in Nutrition (2023)
33. Comparison of Different Obesity Indices for Predicting Incident Hypertension, High Blood Pressure and Cardiovascular Prevention (2017)
34. Investigation of Cardiovascular Risk Factors in Diabetic and Nondiabetic Patients With Nonalcoholic Fatty Liver Disease, Journal of Research in Medical Sciences (2024)
35. Association Between Dietary Insulin Index and Load With Obesity in Adults, European Journal of Nutrition (2020)
36. Assessing Body Shape Index As a Risk Predictor for Cardiovascular Diseases and Metabolic Syndrome Among Iranian Adults, Nutrition (2014)
37. Effects of Gender and Height on the Oral Glucose Tolerance Test: The Isfahan Diabetes Prevention Study, Review of Diabetic Studies (2008)
38. The Impact of Obesity on Hypertension and Diabetes Control Following Healthy Lifestyle Intervention Program in a Developing Country Setting, Journal of Research in Medical Sciences (2011)
39. Impact of Diabesity Phenotype on Cardiovascular Diseases, Major Cardiovascular Events and All-Cause Mortality, Scientific Reports (2023)
40. Novel Anthropometric Indices for Predicting Type 2 Diabetes Mellitus, BMC Public Health (2024)
41. Association Between Type 2 Diabetes and Different Types of Dietary Fats: A Case-Control Study, Clinical Nutrition ESPEN (2023)
42. Associations of Hip Circumference and Height With Incidence of Type 2 Diabetes: The Isfahan Diabetes Prevention Study, Acta Diabetologica (2012)
43. Risk Modeling in Prospective Diabetes Studies: Association and Predictive Value of Anthropometrics, Diabetes and Metabolic Syndrome: Clinical Research and Reviews (2018)
44. The Effects of Macronutrient Intake on the Risk of Pre-Diabetes in First- Degree Relatives of Patients With Type 2 Diabetes, Journal of Isfahan Medical School (2014)
45. Incidence of Metabolic Syndrome and Its Risk Factors Among Type 2 Diabetes Clinic Attenders in Isfahan, Iran, Endokrynologia Polska (2012)
46. Determinants of Incident Prediabetes and Type 2 Diabetes in a 7-Year Cohort in a Developing Country: The Isfahan Cohort Study, Journal of Diabetes (2015)
47. The Characteristics of Pre-Diabetic Patients Associated With Body Composition and Cardiovascular Disease Risk Factors in the Iranian Population, Journal of Research in Medical Sciences (2016)
48. Dietary and Non-Dietary Determinants of Central Adiposity Among Tehrani Women, Public Health Nutrition (2008)
49. Association of Dietary Insulin Index and Dietary Insulin Load With Metabolic Health Status in Iranian Overweight and Obese Adolescents, Frontiers in Nutrition (2022)
50. Heterogeneous Contributions of Change in Population Distribution of Body Mass Index to Change in Obesity and Underweight, eLife (2021)