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The Association Between Dietary Inflammatory Index With Some Cardio-Metabolic Risk Indices Among the Patients With Type 2 Diabetes From Hoveyzeh Cohort Study: A Cross-Sectional Study Publisher Pubmed



Rahimlou M1, 8 ; Ahmadi AR2 ; Cheraghian B3 ; Baghdadi G4 ; Ghalishourani SS5 ; Nozarian S6 ; Hashemi SJ7 ; Rahimi Z3 ; Jahromi NB6 ; Hosseini SA6, 8
Authors
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Authors Affiliations
  1. 1. Department of Nutrition, School of Public Health, Zanjan University of Medical Sciences, Zanjan, Iran
  2. 2. Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Biostatistics and Epidemiology, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  4. 4. Department of Nutrition, School of Public Health, Iran University of Medical Science, Tehran, Iran
  5. 5. Department of Physical Education and Sport Science, Science of Research Branch, Islamic Azad University, Tehran, Iran
  6. 6. Department of Nutritional Sciences, School of Allied Medical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  7. 7. Alimentary Tract Research Center, Clinical Sciences Research Institute, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  8. 8. Nutrition and Metabolic Disease Research Center, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Source: BMC Endocrine Disorders Published:2024


Abstract

Background: The dietary inflammatory index (DII) serves as a tool to assess the inflammatory impact of an individual’s diet. This study aimed to investigate the association between DII and some cardio-metabolic risk indices among patients with T2DM. Methods: Data from the Hoveyzeh Cohort Study, encompassing 2045 adults with T2DM, were analyzed. DII scores were calculated based on food frequency questionnaires. Anthropometric measurements and biochemical tests were performed to assess cardio-metabolic risk factors. Results: Higher DII scores were positively associated with elevated triglyceride levels, triglyceride-glucose (TyG) index, lipid accumulation product (LAP), anthropometric indices including a body shape index (ABSI), body roundness index (BRI), body mass index (BMI), hip, waist circumferences (WC), and waist-to-height ratio (all Ptrend < 0.05). Notably, no significant association was observed between DII and fasting blood sugar (FBS) levels (Ptrend > 0.05). Additionally, dietary intake analysis revealed a negative correlation between DII scores and intake of fiber, fruits, vegetables, legumes, fish, seafood, dairy products, magnesium, and vitamins A, C, D, and E (all Ptrend < 0.05). Conversely, higher DII scores were associated with increased consumption of red meat, processed meat, refined cereals, potatoes, and soft drinks (all Ptrend < 0.05). Conclusion: This study underscores the critical link between dietary inflammation, assessed by the DII score, and a multitude of cardio-metabolic risk factors in patients with T2DM. Notably, while the study did not find a significant association between DII and fasting blood sugar levels, it identified robust associations with novel anthropometric and biochemical indices indicative of cardio-metabolic risk. These findings highlight the potential of dietary interventions as a cornerstone strategy for managing T2DM and mitigating its associated complications. © The Author(s) 2024.
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