Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Risk Factors for In-Hospital Mortality Among Patients With Coronavirus-19 in Isfahan City, Iran Publisher



Riahi R1 ; Ghasemi M2 ; Shatouri ZM3 ; Gharipour M4 ; Maghami M1 ; Melali H5 ; Sami R6 ; Tabatabaei A7 ; Hosseini SM1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Biostatistics and Epidemiology, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Medical Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Biostatistics and Epidemiology, Shahrekord University of Medical Sciences, Shahrekord, Iran
  4. 4. Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Department of Surgery, Isfahan Minimally Invasive Surgery and Obesity Research Center, Amin University Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
  6. 6. Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  7. 7. Department of Education and Research, Hajj and Pilgrimage Medical Center, Tehran, Iran

Source: Advanced Biomedical Research Published:2022


Abstract

Background: The aim of the study is to explore the risk factors of mortality for hospitalized patients in three designated hospitals in Isfahan province. Materials and Methods: This retrospective cohort study was conducted on all positive coronavirus disease (COVID)-19 patients admitted to Khorshid, Isabn Maryam, and Amin hospitals in Isfahan province. The demographic, clinical, laboratory, and outcome data of patients who were died or discharged from February 24, 2020, to April 18, 2020, were extracted from patient’s medical records. Results: Overall 1044 COVID-19 patients were included in this analysis. Based on the findings of this study, older age (≥65 years) (adjusted hazard ratio [aHR]: 2.06; 95% confidence interval [CI]: 1.13–3.76), chronic obstructive pulmonary disease (COPD) history (aHR: 2.52; 95% CI: 1.09–5.83), white blood cell (WBC) counts more than 10 × 10^3/L (aHR: 3.05; 95% CI: 1.42–6.55), Hb level <13 gr/L (aHR: 2.82; 95% CI: 1.34–5.93), bilateral pulmonary infiltrates (aHR: 2.02; 95% CI: 1.12–3.64) at admission, development of acute respiratory distress syndrome (ARDS) (aHR: 1.87; 95% CI: 1.01–3.47), and intensive care unit (ICU) admission (aHR: 2.09; 95% CI: 1.04–4.18) during hospitalization were risk factors for in-hospital mortality in patients with COVID-19. Conclusions: Multiple factors were found related to the severity and death among COVID-19 patients. We were found that older age (≥65 years) with COPD history, high level of WBC, low level of Hb (<13 g/L), bilateral pulmonary infiltrates at admission, development of ARDS, and ICU admission during hospitalization were identified as risk factors of death among COVID-19 patients. More related studies are needed in the future. © 2022 Advanced Biomedical Research.
Related Docs
View other Related Docs
1. Multivariable Analysis of Clinical and Laboratory Data Manifestations Predicting Severity and Mortality Risk in Patients With Coronavirus Disease 2019 in the Mountainous West of Iran: A Retrospective Single-Center Study, Asian Biomedicine (2022)
2. Age-Dependent Clinical Features and Prognosis of Covid-19 Patients, Tanaffos (2021)
3. Severity of Disease and Covid-19 Complications During Hospital Stay: A Prospective Cohort Study, Archives of Iranian Medicine (2022)
4. Association of Systemic Complications With Mortality in Coronavirus Disease of 2019: A Cohort Study on Intensive Care Unit Patients, Journal of Research in Medical Sciences (2022)
5. Evaluation of the Outcome of Covid-19 Disease in Patients Under Mechanical Ventilation Hospitalized in Al-Zahra Hospital, Isfahan in 2019; [بیمارستان الزهرا اصفهان در سال 1299ررسی پیامد بیماري کووید- 19 در بیماران تحت تهویه مکانیکی بستري در], Tehran University Medical Journal (2022)
6. Post-Discharge Health Assessment in Survivors of Coronavirus Disease: A Time-Point Analysis of a Prospective Cohort Study, Quality of Life Research (2023)
7. Risk Factors Associated With Severity and Death From Covid-19 in Iran: A Systematic Review and Meta-Analysis Study, Journal of Intensive Care Medicine (2023)
8. Risk Factors, Clinical, and Laboratory Characteristics of Patients With a Diagnosis of Covid-19, Journal of Emergency Practice and Trauma (2022)
Experts (# of related papers)
View all Related Experts
Nizal Sarrafzadegan (23)
Ramin Sami (21)
Other Related Docs
9. Electrolyte Abnormalities in Hospitalized Covid-19 Patients at Tertiary Referral Centers in Tehran: Hypermagnesemia As a Marker of Fatality: A Retrospective Cross-Sectional Study, Health Science Reports (2023)
10. Rehabilitation, a Necessity in Hospitalized and Discharged People Infected With Covid-19: A Narrative Review, Physical Therapy Reviews (2021)
11. Association of the Medication Protocols and Longitudinal Change of Covid-19 Symptoms: A Hospital-Based Mixed-Statistical Methods Study, Journal of Biopharmaceutical Statistics (2024)
12. The Negative Impact of Obesity on the Occurrence and Prognosis of the 2019 Novel Coronavirus (Covid-19) Disease: A Systematic Review and Meta-Analysis, Eating and Weight Disorders (2022)
13. Cancer Care Management During the Covid-19 Pandemic, Risk Management and Healthcare Policy (2020)
14. Predicting Covid-19 Hospital Stays With Kolmogorov–Gabor Polynomials: Charting the Future of Care, Information (Switzerland) (2023)
15. The Lived Experience of Nurses Caring for Patients With Covid-19 in Iran: A Phenomenological Study, Risk Management and Healthcare Policy (2020)
16. The Clinical Manifestation and Outcome of Covid-19 in Patients With a History of Ischemic Heart Disease; a Retrospective Case-Control Study, BMC Cardiovascular Disorders (2023)
17. Differential Diagnostic Utility of Clinical Laboratory Data in Patients With Severe and Non-Severe Covid-19, Shiraz E Medical Journal (2022)
18. Corona Virus Disease 2019 (Covid-19) and Its Effect on Renal System, a Systematic Review and Meta-Analysis, Iranian Journal of Kidney Diseases (2020)
19. Cardiovascular Risk Factors and Clinical Outcomes Among Patients Hospitalized With Covid-19: Findings From the World Heart Federation Covid-19 Study, Global Heart (2022)
20. Is Non-Invasive Ventilation a Good Choice in All Patients With Severe Covid-19? a Cohort Retrospective Study, Tanaffos (2024)
21. Comparison of Clinical Outcomes, Demographic, and Laboratory Characteristics of Hospitalized Covid-19 Patients During Major Three Waves Driven by Alpha, Delta, and Omicron Variants in Tehran, Iran, Influenza and other Respiratory Viruses (2023)
22. Epidemiological Status and Health System Screening of Covid 19 Hospitalized Patients in Isfahan, Iran, Medical Journal of the Islamic Republic of Iran (2022)
23. Bacterial Infections and Outcomes of Inpatients With Covid-19 in the Intensive Care Unit During the Delta-Dominant Phase: The Worst Wave of Pandemic in Iran, Frontiers in Public Health (2024)
24. Evaluation of Epidemiologic, Clinical and Laboratory Findings of Covid-19 Patients in Intensive Care Units, Alzahra Hospital; [بررسی یافته‌های اپیدمیولوژیک، بالینی و آزمایشگاهی بیماران مبتلا به کووید-19 بستری در بخش‌های مراقبت ویژه بیمارستان الزهرا (س)], Journal of Isfahan Medical School (2024)
25. Absolute Mortality Risk Assessment of Covid-19 Patients: The Khorshid Covid Cohort (Kcc) Study, BMC Medical Research Methodology (2021)
26. Factors Associated With Mortality in Hospitalized Cardiovascular Disease Patients Infected With Covid-19, Immunity, Inflammation and Disease (2022)
27. Temporal Trend of Short-Term Mortality in Acute Myocardial Between 2000-2017: A Multi-Centric Iranian Registry, ARYA Atherosclerosis (2024)
28. Physiologic Scoring Systems in Predicting the Covid-19 Patients’ One-Month Mortality; a Prognostic Accuracy Study, Archives of Academic Emergency Medicine (2022)
29. Demographic, Clinical, and Para Clinical Features in Patients With Covid-19 and St-Elevation Myocardial Infarction; [ویژگیهای دموگرافیک، کلینیکی و پاراکلینیکی در بیماران مبتال به انفارکتوس میوکارد با صعود قطعهی St و بیماری کووید- 91], Journal of Isfahan Medical School (2023)
30. Factors Related to the Hospital Admissions of Covid-19 Patients in the Intensive Care Unit of Selected Iranian Navy Hospitals, Iranian Journal of War and Public Health (2021)
31. Clinical Characteristics of Covid-19-Infected Cancer Patients, Isfahan, Iran, Journal of Research in Medical Sciences (2022)
32. Quality of Life of the Elderly During the Covid-19 Pandemic in Iran; a Cross-Sectional Study, Health Education and Health Promotion (2023)
33. Epidemiological Features of Covid-19 in Iran, Journal of Research in Medical Sciences (2022)
34. Clinical, Laboratory, and Chest Ct Features of Dead Versus Recovered Coronavirus Disease 2019 (Covid-19) Patients: A Multicenter Study, Journal of Health Sciences and Surveillance System (2023)
35. Isfahan Covid Cohort Study: Rationale, Methodology, and Initial Results, Journal of Research in Medical Sciences (2022)
36. Covid-19, an Early Investigation From Exposure to Treatment Outcomes in Tehran, Iran, Journal of Research in Medical Sciences (2021)
37. Baseline Socioeconomic Status Predicting Post-Covid-19 Symptoms: Results From Isfahan Covid Cohort (Icc) Study, Preventive Medicine Reports (2024)
38. Red Blood Cell Distribution Width (Rdw) As a Predictor of In-Hospital Mortality in Covid-19 Patients; a Cross Sectional Study, Archives of Academic Emergency Medicine (2021)
39. The Outcomes of Covid-19 Epidemic Crisis on the Elderly: A Review Study, Journal of Isfahan Medical School (2021)
40. Noncommunicable Disease, Clinical Course and Covid-19 Prognosis: Results Based on I-Core Registry; [Maladies Non Transmissibles, Evolution Clinique Et Pronostic De Covid-19: Resultats Bases Sur Le Registre I-Core], Eastern Mediterranean Health Journal (2021)
41. Risk Factors for the Mortality in Hospitalized Patients With Covid-19: A Brief Report, Iranian Journal of Medical Sciences (2021)
42. Current Status of Covid-19 Pandemic; Characteristics, Diagnosis, Prevention, and Treatment, Journal of Research in Medical Sciences (2020)
43. Asymptomatic Carriers of Coronavirus Disease 2019 Among Healthcare Workers in Isfahan, Iran, Future Virology (2021)
44. Emerging Coronaviruses: First Sars, Second Mers and Third Sars-Cov-2. Epidemiological Updates of Covid-19, Infezioni in Medicina (2020)
45. Covid-19 Information Needs and Information-Seeking Behavior of Cardiovascular Patients: A Qualitative Study, Journal of Consumer Health on the Internet (2022)
46. Nursing Care Challenges for Patients Suffering From Covid-19 From Nurses’ Perspective in Iran: A Descriptive Qualitative Study, Iranian Journal of Nursing and Midwifery Research (2023)
47. Antiviral Mechanisms of Curcumin and Its Derivatives in Prevention and Treatment of Covid-19: A Review, Advances in Experimental Medicine and Biology (2023)
48. Cancer Patients’ Challenges During Covid-19 Pandemic: An Approach to Decision-Making in Management and Policy-Making, Archives of Clinical Infectious Diseases (2021)
49. A Study on the Effect of Aspirin on Clinical Symptoms, Laboratory Indices, and Outcomes in Patients With Covid-19, Journal of Nephropharmacology (2023)
50. Air Pollution and Cardiovascular and Respiratory Disease: Rationale and Methodology of Capacity Study, ARYA Atherosclerosis (2017)