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Antiviral Potential of Melissa Officinalis L.: A Literature Review Publisher



Behzadi A1, 2 ; Imani S3 ; Deravi N4 ; Mohammad Taheri Z5 ; Mohammadian F6 ; Moraveji Z6 ; Shavysi S4 ; Mostafaloo M7 ; Soleimani Hadidi F4 ; Nanbakhsh S1, 2 ; Olangiantehrani S1, 2 ; Marabi MH8 ; Behshood P9 ; Poudineh M10 Show All Authors
Authors
  1. Behzadi A1, 2
  2. Imani S3
  3. Deravi N4
  4. Mohammad Taheri Z5
  5. Mohammadian F6
  6. Moraveji Z6
  7. Shavysi S4
  8. Mostafaloo M7
  9. Soleimani Hadidi F4
  10. Nanbakhsh S1, 2
  11. Olangiantehrani S1, 2
  12. Marabi MH8
  13. Behshood P9
  14. Poudineh M10
  15. Kheirandish A11
  16. Keylani K12
  17. Behfarnia P13
Show Affiliations
Authors Affiliations
  1. 1. School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  2. 2. Tehran, Avicennet, Iran
  3. 3. Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran
  4. 4. Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  5. 5. Hamedan University of Medical Sciences and Health Services, Hamedan, Iran
  6. 6. Shahid Sadoughi University of Medical Sciences, International Campus, Yazd, Iran
  7. 7. School of Nursing and Midwifery, Iran University of Medical Science, Tehran, Iran
  8. 8. Student Research Committee, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran
  9. 9. Department of Microbiology, Young Researchers and Elite Club, Shahrekord Branch, Islamic Azad University, Isfahan, Iran
  10. 10. School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
  11. 11. Student Research Committee, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
  12. 12. School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  13. 13. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Nutrition and Metabolic Insights Published:2023


Abstract

The use of synthetic drugs has increased in recent years; however, herbal medicine is yet more trusted among a huge population worldwide; This could be due to minimal side effects, affordable prices, and traditional beliefs. Lemongrass (Melissa officinalis) has been widely used for reducing stress and anxiety, increasing appetite and sleep, reducing pain, healing wounds, and treating poisonous insect bites and bee stings for a long time. Today, research has shown that this plant can also fight viruses including Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Herpes Simplex Virus (HSV), and Human Immunodeficiency Virus (HIV) through various mechanisms such as inhibiting HSV-1 from binding to host cell, inhibiting HSV-1 replication during the post-adsorption or inhibiting main protease and spike protein of SARS-CoV-2, furthermore, be effective in treating related diseases. This Review investigated the antiviral properties of Melissa officinalis and its effect on viral diseases. More in vitro and in vivo studies are needed to determine Melissa officinaliss underlying mechanism, and more randomized controlled trials should be done to identify its effect in humans. Also, due to the usefulness and lack of side effects, it can be used more as a complementary medicine. © The Author(s) 2023.
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