Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Weight Change, Blood Pressure, Lipids and Glycemic Control Among Patients With Type 2 Diabetes Publisher Pubmed



Janghorbani M1, 2 ; Amini M2 ; Salehimarzijarani M1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan 8144503500, Iran
  2. 2. Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Annals of Nutrition and Metabolism Published:2011


Abstract

Background/Aim: Although weight loss in patients with type 2 diabetes is very important, available data on the effects of long-term weight change on blood pressure (BP), lipids and glycemic control in these patients are limited. The aim of this study was to assess the long-term impact of weight change on BP, plasma lipids and glycemic control among patients with type 2 diabetes receiving routine care. Methods: During the mean [standard deviation (SD)] follow-up period of 9.2 (3.4; range 2-15) years, 7,712 patients with type 2 diabetes were examined to determine changes in weight, BP, plasma lipids and glycemic control using a linear mixed-effects model for repeated measures. The mean (SD) age of participants was 51.3 (10.5) years with a mean (SD) duration of diabetes of 6.3 (6.3) years at initial registration. Results: The change in fasting plasma glucose and glycosylated hemoglobin (HbA1c) from baseline to the last follow-up examination was significantly more favorable in those patients who gained weight during follow-up than in those who lost weight or whose weight remained stable. Systolic and diastolic BP and lipids also rose more significantly in the group with weight gain. Conclusions: Although this population of type 2 diabetes in Iran had negligible weight change over mean 9.2 years, this weight gain was associated with an increase in BP and plasma lipids, but also an improvement in glycemic control. Copyright © 2011 S. Karger AG, Basel.
Experts (# of related papers)
Other Related Docs
16. Associations of Dietary Glycemic Index and Glycemic Load With Glucose Intolerance in Iranian Adults, International Journal of Diabetes in Developing Countries (2014)
25. Relationship Between Dietary Patterns and Incidence of Type 2 Diabetes, International Journal of Preventive Medicine (2019)
30. Glycemic Control Among Iranian People With Type 2 Diabetes: A Systematic Review and Meta-Analysis, International Journal of Diabetes in Developing Countries (2023)
44. Risk of Diabetes According to the Metabolic Health Status and Degree of Obesity, Diabetes and Metabolic Syndrome: Clinical Research and Reviews (2017)
45. Brewer's Yeast Improves Glycemic Indices in Type 2 Diabetes Mellitus, International Journal of Preventive Medicine (2013)