The Quality of Life in Children With Nephritic Syndrome in Isfahan, Iran



Gheissari A¹ ; Farajzadegan Z² ; Shahverdi G³ ; Merikhi A⁴ ; Madihi Y⁴ Show Affiliations
Source: Journal of Isfahan Medical School Published:2013

Abstract

Background: The children with nephrotic syndrome suffer from various complications such as nutritional deprivations, frequent hospitalization and drug side-effects. In this study, we aimed to evaluate the quality of life in children with nephrotic syndrome who have not been progressing to endstage renal disease (ESRD) yet. Methods: In this cross-sectional study, after receiving written consent from both child and his/her parents, children who have nephrotic syndrome, with age of less than 18 years and glomerular filtration rate (GFR) of more than 90 ml/min, were entered. PedsQL Tm 4.0 generic core scale was used for data recording. Demographic and laboratory data, as well as drugs history and period of disease and being responsive or irresponsive to steroids, were recorded and analyzed either. Findings: 25.3% were between 2 to 4 years, 42.7% between 5 to 7 years, 21.3% between 8 to 12 years, and 10.6% were between 13 to 18 years. There was significant statistical difference among groups regarding physical, emotional, social and school performance. The differences between groups were analyzed and the most significant difference was among the children of 5 to 7 years old when considering quality of life in social and school performance. But, we did not find any co-relation between the measured quality of life and paraclinical data. Conclusion: In this study, we concluded that children with nephrotic syndrome need more attention regarding social activities to help them in improving their quality of life.