Quantification of Depth of Anesthesia by Means of Adaptive Calculation of Correlation Dimension Parameters Publisher



Ahmadi B^{1, 2} ; Zaghari B^{1, 2} ; Amirfattahi R^{1, 2} ; Mansouri M² Show Affiliations
Source: Fractals Published:2009

Abstract

This paper proposes an approach for quantifying Depth of Anesthesia (DOA) based on correlation dimension (D2) of electroencephalogram (EEG). The single-channel EEG data was captured in both ICU and operating room while different anesthetic drugs, including propofol and isoflurane, were used. Correlation dimension was computed using various optimized parameters in order to achieve the maximum sensitivity to anesthetic drug effects and to enable real time computation. For better analysis, application of adaptive segmentation on EEG signal for estimating DOA was evaluated and compared to fixed segmentation, too. Prediction probability (PK) was used as a measure of correlation between the predictors and BIS index to evaluate the proposed methods. Appropriate correlation between DOA and correlation dimension is achieved while choosing (D2) parameters adaptively in comparison to fixed parameters due to the nonstationary nature of EEG signal. © 2009 World Scientific Publishing Company.