Suggested Indications of Clinical Practice Guideline for Stem Cell-Therapy in Cardiovascular Diseases: A Stepwise Appropriate Use Criteria for Regeneration Therapy



Behjati M¹ Show Affiliations
Source: ARYA Atherosclerosis Published:2013

Abstract

Despite astonishing progress concerning cardiovascular diseases, patients are still suffering from complications of acute insults. Due to reverse remodeling and improper myocyte rebuilding, heart failure has become a common problem these days which needs more powerful myocardial reconstructing strategies. Indeed, no option cases afflicted with non-healing peripheral vascular diseases; refractory stable and unstable angina is the other field with paucity of proper treatments. For these cases, stem cell-based therapies became optimistic treatment, but lack of guideline-based indications regarding stem-cell is still a major problem which limits application of these cells for such end-stage cases. Here, an outline of appropriateness criteria for stem cell-based therapy is suggested.