Combination of Continuous Wave Co2 Laser and Topical Application of Trichloroacetic Acid 50% Vs Co2 Laser Alone the Treatment of Cutaneous Leishmaniasis (A Case Series of 6 Patients) Publisher Pubmed



Iraji F¹ ; Asilian A¹ ; Heidari A^{1, 2} ; Shariat S¹ ; Bokaie Jazi S^{2, 3} ; Siadat AH²
Source: Journal of Cosmetic Dermatology Published:2020

Abstract

Background: Cutaneous leishmaniasis (CL) is an endemic disease of Iran and despite self-healing nature of this disease and many suggested treatments, scar is usually inevitable results of the affection with this cutaneous infection. CO2 laser in CL has a specific thermolysis effect on infected tissues and application of trichloroacetic acid (TCA) 50% solution for treatment of leishmaniasis scars showed promising results. Aim: To evaluate CO2 laser plus TCA 50% versus CO2 laser alone for treatment of CL. Patients/Methods: In the current report, we present 6 cases of noduloulcerative CL that were treated successfully by the combination of the continuous wave CO2 laser plus topical application of TCA 50%. Results: Five patients improved after 3 weeks of starting treatment, and 1 patient needed to repeat treatment. The scars were flat and good. Conclusions: The CO2 laser plus topical TCA 50% may be more effective in treatment of the cutaneous leishmaniasis and results in shorter healing time. © 2019 Wiley Periodicals, Inc.