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The Protective Effect of Garlic Extract on Diabetic Nephropathy



Rafieiankopaei M1 ; Ghobadi S1 ; Nasri H2
Authors
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Authors Affiliations
  1. 1. Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
  2. 2. Department of Nephrology, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2013

Abstract

Diabetes causes significant changes in urine and serum constituents such as albumin, creatinine, urea nitrogen, and glycated hemoglobin. Garlic extract, however, has been shown to restore all of these biochemicals, and cause histopathological changes. Administration of garlic extract or metformin, or their combinations has also been demonstrated to have both curative and protective effects against gentamicin nephrotoxicity. These findings can potentiate the clinical use of combinations of metformin and garlic extract in the prevention of diabetic nephropathy.
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