Antihypertensive Effect of Iranian Crataegus Curvisepala Lind.: A Randomized, Double-Blind Study

Isfahan University of Medical Sciences

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Antihypertensive Effect of Iranian Crataegus Curvisepala Lind.: A Randomized, Double-Blind Study Pubmed

Asgary S^{1, 3} ; Naderi GH¹ ; Sadeghi M¹ ; Kelishadi R¹ ; Amiri M²

Show Affiliations

1. Isfahan Cardiovasc. Research Center, Isfahan, Iran
2. Department of Epidemiology, Shahrekord University, Shahrekord, Iran
3. Isfahan Cardiovasc. Research Center, Sedigheh Tahereh Hospital, Isfahan, Khorram St. Jomhoori Islami Sq., Iran

Source: Drugs under Experimental and Clinical Research Published:2004

Abstract

The aim of the present study was to investigate the potential antihypertensive effects of extracts of the flavonoid-rich Iranian flower, Crataegus curvisepala Lind., a member of the Rosaceae family. The hydroalcoholic extract of the leaves and flowers were studied in a double-blind, placebo-controlled clinical trial to determine its effects. A total of 92 men and women with primary mild hypertension, aged 40-60 years, were selected and divided randomly into two groups, receiving either hydroalcoholic extract of C. curvisepala Lind. or placebo three times daily for more than 4 months. Blood pressure (BP) was measured each month. Statistical analysis was carried out using Student's t-test. The results obtained showed a significant decrease in both systolic and diastolic BP after 3 months (p < 0.05). C. curvisepala has a time-dependent antihypertensive effect.

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Style	Citing Format
MLA	Asgary S, et al.. "Antihypertensive Effect of Iranian Crataegus Curvisepala Lind.: A Randomized, Double-Blind Study." Drugs under Experimental and Clinical Research, vol. 30, no. 5-6, 2004, pp. 221-225.
APA	Asgary S, Naderi GH, Sadeghi M, Kelishadi R, Amiri M (2004). Antihypertensive Effect of Iranian Crataegus Curvisepala Lind.: A Randomized, Double-Blind Study. Drugs under Experimental and Clinical Research, 30(5-6), 221-225.
Chicago	Asgary S, Naderi GH, Sadeghi M, Kelishadi R, Amiri M. "Antihypertensive Effect of Iranian Crataegus Curvisepala Lind.: A Randomized, Double-Blind Study." Drugs under Experimental and Clinical Research 30, no. 5-6 (2004): 221-225.
Harvard	Asgary S et al. (2004) 'Antihypertensive Effect of Iranian Crataegus Curvisepala Lind.: A Randomized, Double-Blind Study', Drugs under Experimental and Clinical Research, 30(5-6), pp. 221-225.
Vancouver	Asgary S, Naderi GH, Sadeghi M, Kelishadi R, Amiri M. Antihypertensive Effect of Iranian Crataegus Curvisepala Lind.: A Randomized, Double-Blind Study. Drugs under Experimental and Clinical Research. 2004;30(5-6):221-225.
BibTex	@article{ author = {Asgary S and Naderi GH and Sadeghi M and Kelishadi R and Amiri M}, title = {Antihypertensive Effect of Iranian Crataegus Curvisepala Lind.: A Randomized, Double-Blind Study}, journal = {Drugs under Experimental and Clinical Research}, volume = {30}, number = {5-6}, pages = {221-225}, year = {2004} }
RIS	TY - JOUR AU - Asgary S AU - Naderi GH AU - Sadeghi M AU - Kelishadi R AU - Amiri M TI - Antihypertensive Effect of Iranian Crataegus Curvisepala Lind.: A Randomized, Double-Blind Study JO - Drugs under Experimental and Clinical Research VL - 30 IS - 5-6 SP - 221 EP - 225 PY - 2004 ER -