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Neurosarcoidosis: Clinical Features, Diagnosis, and Management Publisher Pubmed



Schwendimann RN1 ; Harris MK1 ; Elliott DG1 ; Menon U1 ; Gonzaleztoledo E1, 2 ; Zivadinov R3 ; Pressly TA4, 5 ; Kelley RE1 ; Hoque R1 ; Fowler M6 ; Maghzi AH7 ; Etemadifar M7 ; Saadatnia M7 ; Minagar A1
Authors
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Authors Affiliations
  1. 1. Departments of 1Neurology, Health Sciences Center, Louisiana State University, Shreveport, LA, United States
  2. 2. Department of Radiology, Health Sciences Center, Louisiana State University, Shreveport, LA, United States
  3. 3. Department of Neurology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, United States
  4. 4. Department of Medicine, Division of Rheumatology, Louisiana State University, Shreveport, LA, United States
  5. 5. Juvenile Arthritis Center, Shriners' Hospital, Shreveport, LA, United States
  6. 6. Department of Pathology, Health Sciences Center, Louisiana State University, Shreveport, LA, United States
  7. 7. Department of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran

Source: American Journal of Therapeutics Published:2013


Abstract

Sarcoidosis is a multisystemic granulomatous disease, which uncommonly affects nervous system. However, when present, it may affect both central and peripheral nervous systems and potentially mimics other chronic diseases of the nervous system. Pathogenesis of neurosarcoidosis remains largely unknown, and its diagnosis and management pose serious challenges to clinicians. Early diagnosis and aggressive treatment of neurosarcoidosis are necessary to produce satisfactory clinical outcomes. This review discusses clinical manifestations, current diagnostic studies, and currently available modalities for management of neurosarcoidosis. © 2013 Lippincott Williams & Wilkins.