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Triglyceride-Glucose Index (Tyg) As a Novel Biomarker in the Era of Cardiometabolic Medicine Publisher Pubmed

Summary: Study finds TyG index may predict diabetes and heart disease risk, aiding early prevention. #Cardiometabolic #HealthScreening

Avagimyan A1 ; Pogosova N2, 3 ; Fogacci F4 ; Aghajanova E5 ; Djndoyan Z6 ; Patoulias D7 ; Sasso LL8 ; Bernardi M9 ; Faggiano A10, 11 ; Mohammadifard N12 ; Neglia D13 ; Carugo S10, 11 ; Cicero A14, 15 ; Rizzo M16, 17 Show All Authors
Authors
  1. Avagimyan A1
  2. Pogosova N2, 3
  3. Fogacci F4
  4. Aghajanova E5
  5. Djndoyan Z6
  6. Patoulias D7
  7. Sasso LL8
  8. Bernardi M9
  9. Faggiano A10, 11
  10. Mohammadifard N12
  11. Neglia D13
  12. Carugo S10, 11
  13. Cicero A14, 15
  14. Rizzo M16, 17
  15. Biondizoccai G9, 18
  16. De Caterina R19
  17. Sarrafzadegan N20, 21

Source: International Journal of Cardiology Published:2025


Abstract

In the period of increasing prevalence of metabolic disorders such as obesity and diabetes, healthcare professionals are facing significant challenges. Therefore, an accurate global assessment of insulin resistance is of utmost importance. Current medical research is focused on identifying an easily accessible and reproducible gold-standard surrogate marker for insulin resistance. Ideally, such a marker would enable healthcare providers to predict the risk of type 2 diabetes and cardiovascular diseases. The triglyceride-glucose index (TyG) is a promising marker for preventive cardiology and cardiometabolic medicine. This narrative review article aims to provide a comprehensive evaluation of the credibility of TyG as a surrogate marker of insulin resistance among patients at different stages across the cardiometabolic continuum. This assessment fully complies with evidence-based medicine and offers valuable insight into the clinical utility of TyG. © 2024
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