Analyzing the Efficacy of Apache Iii Versus Apache Ii on Duration of Mechanical Ventilation and Icu Stay Publisher



Abrishamkar S¹ ; Masoudifar M² ; Sabouri M¹ ; Rouhani F² ; Arrabian M¹ Show Affiliations
Source: Journal of Medical Sciences Published:2010

Abstract

This study have been designed to compare Apache II and Apache III scores as a predictor factors for mechanical ventilation, mortality rate, duration of mechanical ventilation and ICU stay. This is a prospective study conducted in Alzahra General Hospital, Isfahan-Iran University of medical sciences, from September 2005 to September 2006. All patients with respiratory failure due to COPD, Bronchectasis, Asthma, pulmonary edema and pulmonary emboli admitted to ICU, were evaluated. The Apache II and Apache III scores obtained were calculated at admission. Other variables recorded were clinical outcome (dead/survival), mandatory intubation and mechanical ventilation, duration of mechanical ventilation and ICU stay. Correlation between Apache II and Apache III with duration of mechanical ventilation and ICU stay analyzed by Pearson correlation coefficient and p<0.05 considered meaningful. One hundred eighty patients were enrolled, that 38% were women and 62% men. Of the 180 patients 52 (28.9%) died and 128 (71.1%) survived. Correlation between duration of ventilation and Apache II and III were, respectively p = 0.09 and p = 0.019 and correlation between of ICU stay and Apache II and III were p = 0.09 and p = 0.019. Apache III and Apache II both were used to predict outcome and necessity of intubation and mechanical ventilation but Apache III was more significant predictive factor for ICU stay and duration of mechanical ventilation.