Butanol Fraction of Kelussia Odoratissima Mozaff Inhibits the Growth of Leishmania Major Promastigote and Amastigote

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Butanol Fraction of Kelussia Odoratissima Mozaff Inhibits the Growth of Leishmania Major Promastigote and Amastigote Publisher

Summary: Research shows Kelussia odoratissima extract effectively fights Leishmania major, offering a potential natural treatment. #Leishmaniasis #HerbalMedicine

Mirzaei F^{1, 2} ; Norouzi R³ ; Siyadatpanah A⁴ ; Mitsuwan W⁵ ; Nilforoushzadeh M^{6, 7} ; Maleksabet A⁸ ; Hosseini M⁹ ; De Lourdes Pereira M¹⁰ ; Nissapatorn V⁵ ; Hejazi SH^{2, 7}

Source: World's Veterinary Journal Published:2020

Abstract

Naturally derived compounds have been used to treat several infectious diseases including leishmaniasis. The study aimed to investigate the in vitro effects of Kelussia odoratissima Mozaff extract on Leishmania major promastigote and amastigote. Dried leaves of K. odoratissima were fractionated by 3 solvents including aqueous, butanol, and ethyl acetate. The results showed that the butanol fraction of K. odoratissima showed the highest anti-Leishmania effects against L. major promastigotes. Ninety four percent growth inhibition of the promastigote was observed when cells were treated with the 1,280 μg/mL butanol fractions. Moreover, 100% inhibition of amastigotes was detected after treatment with the butanol fraction. Half maximal inhibitory concentration (IC50>) of the butanol fraction in promastigotes and amastigotes was 264.1 and 154.1 μg/mL, respectively. The obtained results suggested the potential medicinal benefits of K. odoratissima butanol fraction as an alternative treatment for leishmaniasis caused by L. major infections. © 2020 Scienceline Publication .

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Butanol Fraction of Kelussia Odoratissima Mozaff Inhibits the Growth of Leishmania Major Promastigote and Amastigote

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Style	Citing Format
MLA	Mirzaei F, et al.. "Butanol Fraction of Kelussia Odoratissima Mozaff Inhibits the Growth of Leishmania Major Promastigote and Amastigote." World's Veterinary Journal, vol. 10, no. 2, 2020, pp. 254-259.
APA	Mirzaei F, Norouzi R, Siyadatpanah A, Mitsuwan W, Nilforoushzadeh M, Maleksabet A, Hosseini M, De Lourdes Pereira M, Nissapatorn V, Hejazi SH (2020). Butanol Fraction of Kelussia Odoratissima Mozaff Inhibits the Growth of Leishmania Major Promastigote and Amastigote. World's Veterinary Journal, 10(2), 254-259.
Chicago	Mirzaei F, Norouzi R, Siyadatpanah A, Mitsuwan W, Nilforoushzadeh M, Maleksabet A, Hosseini M, De Lourdes Pereira M, Nissapatorn V, Hejazi SH. "Butanol Fraction of Kelussia Odoratissima Mozaff Inhibits the Growth of Leishmania Major Promastigote and Amastigote." World's Veterinary Journal 10, no. 2 (2020): 254-259.
Harvard	Mirzaei F et al. (2020) 'Butanol Fraction of Kelussia Odoratissima Mozaff Inhibits the Growth of Leishmania Major Promastigote and Amastigote', World's Veterinary Journal, 10(2), pp. 254-259.
Vancouver	Mirzaei F, Norouzi R, Siyadatpanah A, Mitsuwan W, Nilforoushzadeh M, Maleksabet A, et al.. Butanol Fraction of Kelussia Odoratissima Mozaff Inhibits the Growth of Leishmania Major Promastigote and Amastigote. World's Veterinary Journal. 2020;10(2):254-259.
BibTex	@article{ author = {Mirzaei F and Norouzi R and Siyadatpanah A and Mitsuwan W and Nilforoushzadeh M and Maleksabet A and Hosseini M and De Lourdes Pereira M and Nissapatorn V and Hejazi SH}, title = {Butanol Fraction of Kelussia Odoratissima Mozaff Inhibits the Growth of Leishmania Major Promastigote and Amastigote}, journal = {World's Veterinary Journal}, volume = {10}, number = {2}, pages = {254-259}, year = {2020} }
RIS	TY - JOUR AU - Mirzaei F AU - Norouzi R AU - Siyadatpanah A AU - Mitsuwan W AU - Nilforoushzadeh M AU - Maleksabet A AU - Hosseini M AU - De Lourdes Pereira M AU - Nissapatorn V AU - Hejazi SH TI - Butanol Fraction of Kelussia Odoratissima Mozaff Inhibits the Growth of Leishmania Major Promastigote and Amastigote JO - World's Veterinary Journal VL - 10 IS - 2 SP - 254 EP - 259 PY - 2020 ER -

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