Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Predictors of Metabolic Syndrome in the Iranian Population: Waist Circumference, Body Mass Index, or Waist to Hip Ratio? Publisher



Gharipour M1 ; Sarrafzadegan N1 ; Sadeghi M2 ; Andalib E3 ; Talaie M1 ; Shafie D4 ; Aghababaie E4
Authors
Show Affiliations
Authors Affiliations
  1. 1. Isfahan Cardiovascular Research Centre, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, P.O. Box 81465-1148, Iran
  3. 3. Hypertension Research Centre, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Cardiology Department, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Cholesterol Published:2013


Abstract

This study aimed to investigate whether body mass index (BMI), waist circumference (WC), or waist to hip ratio (WHR) could be a better predictor of metabolic syndrome and, if so, what would be the cutoff points for these surrogates to appropriately differentiate metabolic syndrome in different age and sex subgroups. Methods. The present cross-sectional study was conducted on a sample of Isfahan Cohort Study (ICS). In total, 468 individuals (194 with and 274 subjects without metabolic syndrome) according to the National Cholesterol Education Program's Adult Treatment Panel III (ATP-III) criteria were selected. Anthropometric indices were measured and plotted using receiver-operating characteristic (ROC) curves. Results. According to ROC curve analysis, WC and WHR parameters were better indicators of metabolic syndrome compared to BMI in women, whereas in men WHR had a lower discriminating value compared to the other two parameters. Among these three anthropometric parameters, BMI had a lower sensitivity and WC and WHR both had a higher sensitivity for predicting metabolic syndrome in women compared with in men. The cut points for WC were nearly equal in men and women, 90.3 versus 90.0, respectively. Women had higher cut points for BMI (28.5 kg/m2) compared to men (26.0 kg/m 2). Our results showed the highest sensitivity and specificity for WC cut points specially in women. To predict metabolic syndrome, we looked into optimal age-specific cut points for BMI, WC, and WHR. The results indicated that WC had the highest discriminating value compared to other indicators in the different age subgroups. The optimal cut points for all three parameters gradually increased with age. Conclusion. Our results demonstrated that regardless of gender and age variables, WC could be a preferred parameter for predicting metabolic syndrome compared to BMI and WHR in Iranian population. © 2013 Mojgan Gharipour et al.
Related Docs
View other Related Docs
1. The Cut-Off Values of Anthropometric Indices for Identifying Subjects at Risk for Metabolic Syndrome in Iranian Elderly Men, Journal of Obesity (2014)
2. Assessing Body Shape Index As a Risk Predictor for Cardiovascular Diseases and Metabolic Syndrome Among Iranian Adults, Nutrition (2014)
3. Anthropometric Indices Predicting Incident Type 2 Diabetes in an Iranian Population: The Isfahan Cohort Study, Diabetes and Metabolism (2013)
4. Body Mass Index, Waist-Circumference and Cardiovascular Disease Risk Factors in Iranian Adults: Isfahan Healthy Heart Program, Journal of Health, Population and Nutrition (2013)
5. Determinants of Changes in Metabolic Syndrome Components in a 12-Year Cohort of Iranian Adults, Metabolic Syndrome and Related Disorders (2019)
6. Cardiovascular Disease Risk Factors, Metabolic Syndrome and Obesity in an Iranian Population, Eastern Mediterranean Health Journal (2008)
7. The First Cut-Off Points for Generalized and Abdominal Obesity in Predicting Lipid Disorders in a Nationally Representative Population in the Middle East: The National Survey of Risk Factors for Non-Communicable Diseases of Iran, Archives of Medical Science (2009)
8. Left Ventricular Diastolic Function in Subjects With Metabolic Syndrome: Isfahan Cohort Study, Iranian Heart Journal (2013)
Experts (# of related papers)
View all Related Experts
Roya Kelishadi (210)
Nizal Sarrafzadegan (149)
Other Related Docs
9. Determinants of Incident Metabolic Syndrome in a Middle Eastern Population: Isfahan Cohort Study, Metabolic Syndrome and Related Disorders (2017)
10. Paediatric Metabolic Syndrome and Associated Anthropometric Indices: The Caspian Study, Acta Paediatrica, International Journal of Paediatrics (2006)
11. Multiparity and Risk of Metabolic Syndrome: Isfahan Healthy Heart Program, Metabolic Syndrome and Related Disorders (2009)
12. Metabolic Syndrome: An Emerging Public Health Problem in Iranian Women: Isfahan Healthy Heart Program, International Journal of Cardiology (2008)
13. Tri-Ponderal Mass Index and Body Mass Index in Prediction of Pediatric Metabolic Syndrome: The Caspian-V Study, Archives of Endocrinology and Metabolism (2020)
14. Assessing Metabolic Syndrome Through Increased Heart Rate During Exercise, Acta Medica Iranica (2016)
15. Appropriate Cut-Off Values of Waist Circumference to Predict Cardiovascular Outcomes: 7-Year Follow-Up in an Iranian Population, Internal Medicine (2012)
16. First Nationwide Study of the Prevalence of the Metabolic Syndrome and Optimal Cutoff Points of Waist Circumference in the Middle East: The National Survey of Risk Factors for Noncommunicable Diseases of Iran, Diabetes Care (2009)
17. Association of a Body Shape Index and Hip Index With Cardiometabolic Risk Factors in Children and Adolescents: The Caspian-V Study, Journal of Diabetes and Metabolic Disorders (2021)
18. Utility of Waist Circumference-To-Height Ratio As a Screening Tool for Generalized and Central Obesity Among Iranian Children and Adolescents: The Caspian-V Study, Pediatric Diabetes (2019)
19. Anthropometric Assessment to Predict Hypertension Among Women in Tehran, Iran, Tehran University Medical Journal (2008)
20. Impact of Metabolic Syndrome on Ischemic Heart Disease - a Prospective Cohort Study in an Iranian Adult Population: Isfahan Cohort Study, Nutrition, Metabolism and Cardiovascular Diseases (2012)
21. Association of Lipid Accumulation Product With Cardio-Metabolic Risk Factors in Postmenopausal Women, Acta Medica Iranica (2016)
22. Are Non-High-Density Lipoprotein Fractions Associated With Pediatric Metabolic Syndrome? the Caspian-V Study, Lipids in Health and Disease (2018)
23. Cholesterol to Saturated Fat Index (Csi), Metabolic Parameters and Inflammatory Factors Among Obese Individuals, BMC Endocrine Disorders (2024)
24. The Relationship Between Diet Quality Index and Components of Metabolic Syndrome, Journal of Health System Research (2024)
25. Apopulation-Based Metabolic Syndrome Risk Score and Its Determinants: The Isfahan Healthy Heart Program, Journal of Research in Medical Sciences (2014)
26. Adherence to Healthy Eating Index-2010 Is Inversely Associated With Metabolic Syndrome and Its Features Among Iranian Adult Women, European Journal of Clinical Nutrition (2017)
27. Association of Anthropometric Indices With Metabolic Phenotypes of Obesity in Children and Adolescents: The Caspian-V Study, Frontiers in Endocrinology (2019)
28. Cardiovascular Disease Risk Assessment: Triglyceride/High-Density Lipoprotein Versus Metabolic Syndrome Criteria, Journal of Research in Health Sciences (2019)
29. Reference Curves of Anthropometric Indices and Serum Lipid Profiles in Representative Samples of Asian and European Children, Archives of Medical Science (2008)
30. Anthropometric Indices Associated With Dyslipidemia in Obese Children and Adolescents: A Retrospective Study in Isfahan, ARYA Atherosclerosis (2011)
31. Predicting the 10-Year Incidence of Dyslipidemia Based on Novel Anthropometric Indices, Using Data Mining, Lipids in Health and Disease (2024)
32. Dietary Energy Density and the Metabolic Syndrome Among Iranian Women, European Journal of Clinical Nutrition (2011)
33. Socioeconomic and Reproductive Determinants of Waist-Hip Ratio Index in Menopausal Women, Journal of Mid-Life Health (2017)
34. The Metabolic Syndrome in Hypertensive and Normotensive Subjects: The Isfahan Healthy Heart Programme, Annals of the Academy of Medicine Singapore (2005)
35. Correlation of Circulating Inflammatory Markers, Ghrelin, Adiponectin With Obesity Indices in Subjects With Metabolic Syndrome, Pakistan Journal of Medical Sciences (2013)
36. Adherence to a Healthy Diet and Odds of Metabolic Syndrome: A Cross-Sectional Study, Clinical Nutrition ESPEN (2023)
37. First Report on the Validity of a Continuous Metabolic Syndrome Score As an Indicator for Metabolic Syndrome in a National Sample of Paediatric Population - the Caspian-Iii Study, Endokrynologia Polska (2013)
38. Association of Glycaemic Index and Glycaemic Load With Metabolic Syndrome in an Iranian Adult Population: Isfahan Healthy Heart Program, Nutrition and Dietetics (2017)
39. Evaluating the Relation Between Metabolic Syndrome and Its Components With Low Ankle to Brachial Index in an Iranian Population, Journal of Isfahan Medical School (2011)
40. Adherence to Lifelines Diet Score and Risk Factors of Metabolic Syndrome Among Overweight and Obese Adults: A Cross-Sectional Study, Frontiers in Nutrition (2022)
41. Obesity and Metabolic Syndrome Among a Representative Sample of Iranian Adolescents, Southeast Asian Journal of Tropical Medicine and Public Health (2012)
42. Prevalence of Metabolic Syndrome According to Atpiii and Idf Criteria in the Iranian Population, Koomesh (2012)
43. The Relationship Between Hematologic Variables and Metabolic Syndrome, Iranian Heart Journal (2011)
44. Anthropometric Indicators of Adiposity Related to Body Weight and Body Shape As Cardiometabolic Risk Predictors in British Young Adults: Superiority of Waist-To-Height Ratio, Journal of Obesity (2018)
45. Validity of Triglyceride–Glucose Index As an Indicator for Metabolic Syndrome in Children and Adolescents: The Caspian-V Study, Eating and Weight Disorders (2018)
46. Association of Anthropometric Indices With Continuous Metabolic Syndrome in Children and Adolescents: The Caspian-V Study, Eating and Weight Disorders (2018)
47. Validity of Self-Reported Height, Weight, Body Mass Index, and Waist Circumference in Iranian Adults, International Journal of Preventive Medicine (2021)
48. Association of Anthropometric Measures With Cardiovascular Risk Factors and Metabolic Syndrome in Normal-Weight Children and Adolescents: The Caspian Iii Study, Obesity Facts (2013)
49. Correlation of Dyslipidemia With Waist to Height Ratio, Waist Circumference, and Body Mass Index in Iranian Adults, Asia Pacific Journal of Clinical Nutrition (2007)
50. Dietary and Non-Dietary Determinants of Central Adiposity Among Tehrani Women, Public Health Nutrition (2008)