Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Prevalence of Congenital Hypothyroidism in Isfahan, Iran: Results of a Survey on 20,000 Neonates Publisher Pubmed



Hashemipour M1, 2, 6 ; Amini M1, 2 ; Iranpour R2 ; Sadri GH3 ; Javaheri N1 ; Haghighi S1 ; Hovsepian S1 ; Javadi AA4 ; Nematbakhsh M5 ; Sattari G1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Isfahan Endocr. and Metab. Res. Ctr., School of Medicine, Isfahan, Iran
  2. 2. Department of Pediatrics, School of Medicine, Isfahan, Iran
  3. 3. Department of Social Medicine, School of Medicine, Isfahan, Iran
  4. 4. Department of Infectious Diseases, School of Medicine, Isfahan, Iran
  5. 5. Department of Physiology, School of Medicine, Isfahan Univ. Med. Sci. Hlth. Serv., Isfahan, Iran
  6. 6. Isfahan Endocr. and Metab. Res. Ctr., Sedigheh Tahereh Med. Res. Complex, Isfahan 8187698191, Khorram Street, Iran

Source: Hormone Research Published:2004


Abstract

Aims: To evaluate the prevalence of congenital hypothyroidism (CH) in a screening program performed for the first time in Isfahan, Iran. Methods: From May 2002 to December 2002, T4 and TSH serum concentrations of 20,000 3- to 7-day-old newborns, born in all 17 hospitals of the city, were measured by radioimmunoassay and immunoradiometric assay, respectively. The newborns with abnormal screening results (TSH >20 mIU/l, T4 <6.5 μg/dl and based on the weight) were re-examined. Results: Of 531 recalled subjects (recall rate 2.6%), 54 were confirmed to be hypothyroid, showing a prevalence of 1:370 for CH. Conclusion: Considering the high frequency of CH, the necessity of implementing a routine screening program in the healthcare system of Isfahan Province is emphasized. Copyright © 2004 S. Karger AG, Basel.
Other Related Docs
13. Prevalence of Transient Congenital Hypothyroidism in Central Part of Iran, Journal of Research in Medical Sciences (2013)
27. Congenital Cardiac Malformations in Congenital Hypothyroid Patients in Isfahan, Journal of Research in Medical Sciences (2006)
29. Age of Menarche and Final Height in Patients With Permanent Congenital Hypothyroidism, Annals of Pediatric Endocrinology and Metabolism (2024)
38. The Role of Ultrasonography in Primary Congenital Hypothyroidism, Journal of Research in Medical Sciences (2011)
39. Spatial Distribution of Congenital Hypothyroidism, Archives of Iranian Medicine (2021)
40. Guideline for the Treatment of Hypothyroidism in Prematurity, International Journal of Preventive Medicine (2021)
46. Hearing Impairment in Congenitally Hypothyroid Patients, Iranian Journal of Pediatrics (2012)
47. Different Aspects of Kidney Function in Well-Controlled Congenital Hypothyroidism, JCRPE Journal of Clinical Research in Pediatric Endocrinology (2012)
50. Isfahan Thyroid Cohort Study (Itcs), Archives of Iranian Medicine (2021)