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Applications of Chemically Modified Carbon Nanotubes for Tissue Engineering Publisher



Esmaeili Y1 ; Mirahmadizare SZ2 ; Bigham A3 ; Boshtam M4 ; Gharghish S5 ; Zomorrodi R6
Authors
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Authors Affiliations
  1. 1. Isfahan University of Medical Sciences, Biosensor Research Center, School of Advanced Technologies in Medicine, Hezarjerib Ave, Isfahan, 8174673461, Iran
  2. 2. Royan Institute for Biotechnology, ACECR, Reproductive Biomedicine Research Center, Department of Animal Biotechnology, Isfahan, 8159358686, Iran
  3. 3. Institute of Polymers, Composites and Biomaterials-National Research Council (IPCB-CNR), Viale J.F. Kennedy 54-Mostra d’Oltremare pad. 20, Naples, 80125, Italy
  4. 4. Isfahan University of Medical Sciences, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan, 8158388994, Iran
  5. 5. Tabriz University of Medical Science, Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Tabriz, 5154853431, Iran
  6. 6. Islamic Azad University, Department of Chemistry, Science and Research Branch, Simon Bulivar Blvd, Tehran, 1477893855, Iran

Source: Chemically Modified Carbon Nanotubes for Commercial Applications Published:2022


Abstract

Advances in carbon nanotube production and chemical modifications have significant effects on biomedical applications, including tissue engineering and regenerative medicine. Unique properties of carbon nanotubes such as a high surface-area-to-volume ratio, tailorable characteristics, and optical properties have made them a potential candidate for sensing microenvironments, tracking cells, and delivering therapeutic agents, as well as scaffolding for integration into the host’s body. Indeed, because of the biocompatibility and hemocompatibility of carbon structures, they can be used as fibers in artificial organs as a strengthening agent or as implant coating materials. This chapter summarizes the faithful applications of carbon nanotubes, their rational modifications, and current shortcomings in tissue engineering, with a focus on their usage in bone, nerve, and cardiac tissue regeneration. Overall, this chapter offers carbon nanotubes as a promising mechanistic infrastructure for the next-generation tissue engineering and regenerative medicine. © 2023 WILEY-VCH GmbH, Boschstr. 69469 Weinheim, Germany.
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