Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
A Review on the Genetic, Environmental, and Lifestyle Aspects of the Early-Life Origins of Cardiovascular Disease Publisher Pubmed



Kelishadi R1, 2 ; Poursafa P3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Child Growth and Development Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Environment Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Current Problems in Pediatric and Adolescent Health Care Published:2014


Abstract

This article is a comprehensive review on developmental origins of health and disease regarding various factors related to the origins of cardiovascular diseases from early life. It presents a summary of the impacts of various factors such as epigenetics; gene-environment interaction; ethnic predisposition to cardiovascular diseases and their underlying risk factors; prenatal factors; fetal programming; maternal weight status and weight gain during pregnancy; type of feeding during infancy; growth pattern during childhood; obesity; stunting; socioeconomic status; dietary and physical activity habits; active, secondhand, and thirdhand smoking, as well as environmental factors including air pollution and global climate change on the development and progress of cardiovascular diseases and their risk factors. The importance of early identification of predisposing factors for cardiovascular diseases for primordial and primary prevention of cardiovascular diseases from early life is highlighted. © 2014 Mosby, Inc.
Related Docs
View other Related Docs
1. Gene-Environment Interaction in Origins of Chronic Non-Communicable Disease, Gene-Environment Interactions and Human Diseases (2016)
2. Low Birthweight or Rapid Catch-Up Growth: Which Is More Associated With Cardiovascular Disease and Its Risk Factors in Later Life? a Systematic Review and Cryptanalysis, Paediatrics and International Child Health (2015)
3. Duration of Breast-Feeding and Cardiovascular Risk Factors Among Iranian Children and Adolescents: The Caspian Iii Study, Nutrition (2013)
4. Overweight, Air and Noise Pollution: Universal Risk Factors for Pediatric Pre-Hypertension, Journal of Research in Medical Sciences (2011)
5. Role of Environmental Chemicals in Obesity: A Systematic Review on the Current Evidence, Journal of Environmental and Public Health (2013)
6. Air Pollution and Non-Respiratory Health Hazards for Children, Archives of Medical Science (2010)
7. Pediatric Metabolic Syndrome: From Prevention to Treatment, Cholesterol (2012)
8. Is Air Quality Index Associated With Cardiometabolic Risk Factors in Adolescents? the Caspian-Iii Study, Environmental Research (2014)
Experts (# of related papers)
View all Related Experts
Roya Kelishadi (110)
Marjan Mansourian (17)
Other Related Docs
9. National and Sub-National Prevalence, Trend, and Burden of Cardiometabolic Risk Factors in Iranian Children and Adolescents, 1990 - 2013, Archives of Iranian Medicine (2014)
10. Factor Analysis of Markers of Inflammation and Oxidation and Echocardiographic Findings in Children With a Positive Family History of Premature Coronary Heart Disease, Pediatric Cardiology (2009)
11. The Effects of Climate Change and Air Pollution on Children and Mothers' Health, Global Climate Change and Public Health (2014)
12. Association of Cell Blood Counts and Cardiometabolic Risk Factors Among Young Obese Children, Saudi Medical Journal (2011)
13. Dual Burden of Body Weight Among Iranian Children and Adolescents in 2003 and 2010: The Caspian-Iii Study, Archives of Medical Science (2014)
14. An Overview on the Successes, Challenges and Future Perspective of a National School-Based Surveillance Program: The Caspian Study, Journal of Diabetes and Metabolic Disorders (2014)
15. Reference Curves of Anthropometric Indices in Two National Studies Conducted Among Iranian Children in 2003-2004 and 2009-2010: The Caspian Study, Journal of Research in Medical Sciences (2014)
16. Is Duration of Breastfeeding Associated With Anthropometric Measures in Children and Adolescents? the Weight Disorders Survey of the Caspian- Iv Study, International Journal of Pediatrics (2016)
17. First Reference Curves of Waist Circumference for German Children in Comparison to International Values: The Pep Family Heart Study, World Journal of Pediatrics (2008)
18. Effect of Particulate Air Pollution and Passive Smoking on Surrogate Biomarkers of Endothelial Dysfunction in Healthy Children, Paediatrics and International Child Health (2014)
19. Inflammation-Induced Atherosclerosis As a Target for Prevention of Cardiovascular Diseases From Early Life, Open Cardiovascular Medicine Journal (2010)
20. Association of Exposure to Fine Particulate Matter and Risk Factors of Non-Communicable Diseases in Children and Adolescents, International Journal of Pediatrics (2017)
21. Obesity and Air Pollution: Global Risk Factors for Pediatric Non-Alcoholic Fatty Liver Disease, Hepatitis Monthly (2011)
22. The Prospective Epidemiological Research Studies in Iran (Persian) Birth Cohort Protocol: Rationale, Design and Methodology, Longitudinal and Life Course Studies (2021)
23. Association of Serum Lead and Mercury Level With Cardiometabolic Risk Factors and Liver Enzymes in a Nationally Representative Sample of Adolescents: The Caspian-Iii Study, Environmental Science and Pollution Research (2014)
24. Association of Early Life Factors With Dyslipidemia in Children and Adolescents: The Caspian-V Study, Health Promotion Perspectives (2020)
25. Percentiles for Anthropometric Measures in Iranian Children and Adolescents: The Caspian-Iv Study, Journal of Pediatric Endocrinology and Metabolism (2016)
26. Height-Adjusted Percentiles Evaluated Central Obesity in Children and Adolescents More Effectively Than Just Waist Circumference, Acta Paediatrica, International Journal of Paediatrics (2017)
27. Ethnic Disparities of the Metabolic Syndrome in Population-Based Samples of German and Iranian Adolescents, Metabolic Syndrome and Related Disorders (2010)
28. Estimating Population Attributable Risk Fraction of Determinants of Pediatric Obesity, BMC Public Health (2025)
29. Lipid Regulatory Genes Polymorphism in Children With and Without Obesity and Cardiometabolic Risk Factors: The Caspian-Iii Study, Journal of Research in Medical Sciences (2018)
30. Effects of a Lifestyle Modification Trial Among Phenotypically Obese Metabolically Normal and Phenotypically Obese Metabolically Abnormal Adolescents in Comparison With Phenotypically Normal Metabolically Obese Adolescents, Maternal and Child Nutrition (2010)
31. Is Prehypertension a Risk Factors for Cardiovascular Diseases Among Iranian Women?, Journal of Research in Medical Sciences (2012)
32. The Association of Birth Weight With Cardiovascular Risk Factors and Mental Problems Among Iranian School-Aged Children: The Caspian-Iii Study, Nutrition (2014)
33. First Report on the Lipid Profile Late After Kawasaki Disease in Iranian Children, International Journal of Preventive Medicine (2014)
34. Genetic Association With Low Concentrations of High Density Lipoprotein-Cholesterol in a Pediatric Population of the Middle East and North Africa: The Caspian-Iii Study, Atherosclerosis (2014)
35. Obesity and Metabolic Syndrome Among a Representative Sample of Iranian Adolescents, Southeast Asian Journal of Tropical Medicine and Public Health (2012)
36. Geographical Distribution of Growth Disorders in Iranian Children and Adolescents: The Caspian-Iv Study, Iranian Journal of Public Health (2015)
37. A Systematic Review of Studies on Blood Pressure in Iranian Pediatric Population: First Report From the Middle East and North Africa, Iranian Journal of Pediatrics (2016)
38. Childhood Overweight, Obesity, and the Metabolic Syndrome in Developing Countries, Epidemiologic Reviews (2007)
39. Pediatric Metabolic Syndrome and Cell Blood Counts: Bivariate Bayesian Modeling, Journal of Tropical Pediatrics (2014)
40. An Overview of a National Surveillance Program in Iran for Prevention of Chronic Non-Communicable Diseases From Childhood: Caspian Study, Iranian Journal of Public Health (2009)
41. Metabolic Syndrome and Its Determinants in a Sample of Young Iranian Children With Obesity, Pakistan Journal of Medical Sciences (2013)
42. First Report on Path Analysis for Cardiometabolic Components in a Nationally Representative Sample of Pediatric Population in the Middle East and North Africa (Mena): The Caspian-Iii Study, Annals of Nutrition and Metabolism (2013)
43. Macro- and Micronutrients of Human Milk Composition: Are They Related to Maternal Diet? a Comprehensive Systematic Review, Breastfeeding Medicine (2017)
44. Risk Factors of Congenital Heart Diseases: A Hospital-Based Case-Control Study in Isfahan, Iran, ARYA Atherosclerosis (2020)
45. Trends in Health Burden of Ambient Particulate Matter Pollution in Iran, 1990–2010: Findings From the Global Burden of Disease Study 2010, Environmental Science and Pollution Research (2015)
46. The Thickness of the Intimal and Medial Layers of the Carotid Arteries, and the Index of Left Ventricular Mass, in Children of Patients With Premature Coronary Arterial Disease, Cardiology in the Young (2007)
47. Prevalence of Prehypertension and Hypertension in a Nationally Representative Sample of Iranian Children and Adolescents: The Caspian-Iv Study, International Journal of Preventive Medicine (2014)
48. First Report on the Association of Drinking Water Hardness and Endothelial Function in Children and Adolescents, Archives of Medical Science (2014)
49. Probiotics As a Novel Treatment for Non-Alcoholic Fatty Liver Disease; a Systematic Review on the Current Evidences, Hepatitis Monthly (2013)
50. Factors Associated With Insulin Resistance and Non-Alcoholic Fatty Liver Disease Among Youths, Atherosclerosis (2009)