Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Sars-Cov-2 Vaccines: A Double-Edged Sword Throughout Rapid Evolution of Covid-19 Publisher Pubmed



Zolfaghari MA1, 2 ; Ghadiri Moghaddam F3 ; Rajput S4 ; Karimi A2, 5 ; Naghi Vishteh M6 ; Mahmoodpoor A7 ; Dolati S8 ; Yousefi M9, 10
Authors
Show Affiliations
Authors Affiliations
  1. 1. Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
  2. 2. Department of Molecular Medicine, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
  3. 3. Department of Biology, Faculty of Science, Azarbaijan Shahid Madani University, Tabriz, Iran
  4. 4. Department of Pediatrics, School of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran
  5. 5. Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  6. 6. Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  7. 7. Department of Anesthesiology, Tabriz University of Medical Sciences, Tabriz, Iran
  8. 8. Physical Medicine and Rehabilitation Research Center, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran
  9. 9. Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  10. 10. Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

Source: Cell Biology International Published:2022


Abstract

After more than 2 years of the coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome coronavirus 2, several questions have remained unanswered that affected our daily lives. Although substantial vaccine development could resist this challenge, emerging new variants in different countries could be considered as potent concerns regarding the adverse effects of reinfection or postvaccination. Precisely, these concerns address some significant and probable outcomes in vaccinated or reinfected models, followed by some virus challenges, such as antibody-dependent enhancement and cytokine storm. Therefore, the importance of evaluating the effectiveness of neutralizing antibodies (nAbs) elicited by vaccination and the rise of new variants must be addressed. © 2022 International Federation for Cell Biology.
Related Docs
View other Related Docs
1. Covid-19 Pandemic: Insights Into Genetic Susceptibility to Sars-Cov-2 and Host Genes Implications on Virus Spread, Disease Severity and Outcomes, Human Antibodies (2022)
2. Novel and Emerging Mutations of Sars-Cov-2: Biomedical Implications, Biomedicine and Pharmacotherapy (2021)
3. Genetics and Genomics of Sars-Cov-2: A Review of the Literature With the Special Focus on Genetic Diversity and Sars-Cov-2 Genome Detection, Genomics (2021)
4. Sars-Cov-2 (Covid-19): New Discoveries and Current Challenges, Applied Sciences (Switzerland) (2020)
5. Covid-19 Vaccines: Current and Future Challenges, Frontiers in Pharmacology (2024)
6. Nanobased Platforms for Diagnosis and Treatment of Covid-19: From Benchtop to Bedside, ACS Biomaterials Science and Engineering (2021)
7. Mesenchymal Stem Cells: A Potent Cell Source for Covid-19, Coronaviruses (2021)
8. The Immunological Therapeutic Strategies for Controlling Multiple Sclerosis: Considerations During the Covid-19 Pandemic, Biomolecules (2021)
Experts (# of related papers)
View all Related Experts
Shaghayegh Haghjooy Javanmard (13)
Behrooz Ataei (9)
Other Related Docs
9. Covid-19 Vaccine Boosters: The Good, the Bad, and the Ugly, Vaccines (2021)
10. Epidemiology, Virology, Clinical Features, Diagnosis, and Treatment of Sars-Cov-2 Infection, Journal of Experimental and Clinical Medicine (Turkey) (2021)
11. Current Status of Covid-19 Pandemic; Characteristics, Diagnosis, Prevention, and Treatment, Journal of Research in Medical Sciences (2020)
12. Immune and Bioinformatics Identification of T Cell and B Cell Epitopes in the Protein Structure of Sars-Cov-2: A Systematic Review, International Immunopharmacology (2020)
13. Cancer Care Management During the Covid-19 Pandemic, Risk Management and Healthcare Policy (2020)
14. Sars-Cov-2, Sars and Mers: Three Formidable Coronaviruses Which Have Originated From Bats; [Sars-Cov-2, Sars-Cov I Mers-Cov: Trzy Grozne Koronawirusy Pochodzace Od Nietoperzy], Postepy Higieny i Medycyny Doswiadczalnej (2021)
15. A Review of Novel Coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2), Iranian Journal of Medical Microbiology (2020)
16. Cytokines and Micrornas in Sars-Cov-2: What Do We Know?, Molecular Therapy Nucleic Acids (2022)
17. Emerging Technologies for the Treatment of Covid-19, Advances in Experimental Medicine and Biology (2021)
18. Aspects of Epidemiology, Pathology, Virology, Immunology, Transmission, Prevention, Prognosis, Diagnosis, and Treatment of Covid.19 Pandemic: A Narrative Review, International Journal of Preventive Medicine (2021)
19. A Comprehensive Review of Therapeutic Options for Covid-19, Ethiopian Journal of Health Development (2022)
20. Recent Findings of Coronavirus: The Pathogenesis and Treatment, Journal of Isfahan Medical School (2020)
21. Covid-19 Management in the Emergency Ward, Journal of Research in Medical Sciences (2021)
22. Prevention of Covid-19: Preventive Strategies for General Population, Healthcare Setting, and Various Professions, Advances in Experimental Medicine and Biology (2021)
23. Potential Immune Indicators for Predicting the Prognosis of Covid-19 and Trauma: Similarities and Disparities, Frontiers in Immunology (2022)
24. Nervous System Involvement in Covid-19: A Review of the Current Knowledge, Molecular Neurobiology (2021)
25. Classification of Viral Proteins Expressed by the Sars-Cov-2 Genome, Acta Microbiologica Hellenica (2022)
26. Efficacy and Side Effects of Sputnik V, Sinopharm and Astrazeneca Vaccines to Stop Covid-19; a Review and Discussion, Immunopathologia Persa (2021)
27. Impact of Sars-Cov-2 Pandemic on Patients With Primary Immunodeficiency, Journal of Clinical Immunology (2021)
28. Cardiovascular Complications of Sars-Cov-2 Vaccines: An Overview, Cardiology and Therapy (2022)
29. Effect of Polyphenols Against Complications of Covid-19: Current Evidence and Potential Efficacy, Pharmacological Reports (2024)
30. Convalescent Plasma Therapy for Covid-19: Lessons From Sars-Cov, Mers-Cov, and H1n1 Infection, Acta Medica Indonesiana (2021)
31. Epidemiological Study of Covid-19 in Iran and the World: A Review Study, Infectious Disorders - Drug Targets (2022)
32. Covid-19 and Substance Use Disorders: Recommendations to a Comprehensive Healthcare Response. an International Society of Addiction Medicine Practice and Policy Interest Group Position Paper, Basic and Clinical Neuroscience (2020)
33. Thymus Vulgaris, a Natural Pharmacy Against Covid-19: A Molecular Review, Journal of Herbal Medicine (2023)
34. Characterizing the Immune Responses of Those Who Survived or Succumbed to Covid-19: Can Immunological Signatures Predict Outcome?, Cytokine (2021)
35. Vaccine Design and Delivery Approaches for Covid-19, International Immunopharmacology (2021)
36. Association of Clinical Features With Spike Glycoprotein Mutations in Iranian Covid-19 Patients, Journal of Clinical Medicine (2022)
37. Cancer Occurrence As the Upcoming Complications of Covid-19, Frontiers in Molecular Biosciences (2022)
38. Evaluation of Anti-Sars-Cov-2 Rbd Antibody Response After Booster Dose of Spikogen® in Individuals With Two Previous Doses of Sinopharm and Its Association With Hla-Dr and -Dq Alleles, Human Immunology (2025)
39. Association of Prior Covid‑19 Infection With Risk of Breakthrough Infection Following Vaccination: A Cohort Study in Isfahan, Iran, International Journal of Preventive Medicine (2024)
40. Pulmonary Function, Anxiety, Depression, and Sleep Quality After Recovery From Covid-19, Tanaffos (2023)
41. Exploring the Out of Sight Antigens of Sars-Cov-2 to Design a Candidate Multi-Epitope Vaccine by Utilizing Immunoinformatics Approaches, Vaccine (2020)
42. Cardiovascular Complications of Covid-19 Vaccines: A Review of Case-Report and Case-Series Studies, Heart and Lung (2023)
43. A Mini-Review on Sofosbuvir and Daclatasvir Treatment in Coronavirus Disease 2019, New Microbes and New Infections (2021)
44. Use of Complementary and Alternative Medicine in General Population During Covid-19 Outbreak: A Survey in Iran, Journal of Integrative Medicine (2022)
45. Outcomes of Cerebral Venous Thrombosis Due to Vaccine-Induced Immune Thrombotic Thrombocytopenia After the Acute Phase, Stroke (2022)
46. Using in Silico Bioinformatics Algorithms for the Accurate Prediction of the Impact of Spike Protein Mutations on the Pathogenicity, Stability, and Functionality of the Sars-Cov-2 Virus and Analysis of Potential Therapeutic Targets, Biochemical Genetics (2023)
47. The Potential Effect of Royal Jelly on Biomarkers Related to Covid-19 Infection and Severe Progression, Advances in Experimental Medicine and Biology (2023)
48. Conceptual Framework for Sars-Cov-2-Related Lymphopenia, Advanced Biomedical Research (2022)
49. Sars-Cov-2 Serology Among People With Multiple Sclerosis on Disease-Modifying Therapies After Bbibp-Corv (Sinopharm) Inactivated Virus Vaccination: Same Story, Different Vaccine, Multiple Sclerosis and Related Disorders (2022)
50. Fulminant Neuromyelitis Optica Spectrum Disorder (Nmosd) Following Covid-19 Vaccination: A Need for Reconsideration?, Multiple Sclerosis and Related Disorders (2022)