Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Vaccine Production by Recognizing the Functional Mechanisms of Covid-19 Publisher



Mirzaei A1 ; Taheri D2 ; Reis LO3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Isfahan Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Urology, UroScience, State University of Campinas, Unicamp and Pontifical Catholic University of Campinas, PUC-Campinas, SP, Campinas, Brazil

Source: Translational Research in Urology Published:2020


Abstract

With the rapid worldwide spread of a new coronavirus with the scientific name severe acute respiratory syndrome coronavirus (SARS-CoV-2) at the beginning of 2020, attempts to produce a vaccine started in different countries. This study aimed to review the mechanisms and functions of the coronavirus protein as a basis for vaccine production. A rapid review of available studies is conducted. Related information was extracted and summarized, compared, and discussed with regards to the coronavirus mechanisms and acts as a pathogen, including apoptosis and autophagy. An overview of available information on coronavirus functional mechanisms was performed to aid researchers in the development and production of vaccines against it. © 2020 Urology Research Center (URC).
Related Docs
View other Related Docs
1. Sars-Cov-2, Sars and Mers: Three Formidable Coronaviruses Which Have Originated From Bats; [Sars-Cov-2, Sars-Cov I Mers-Cov: Trzy Grozne Koronawirusy Pochodzace Od Nietoperzy], Postepy Higieny i Medycyny Doswiadczalnej (2021)
2. Nanobased Platforms for Diagnosis and Treatment of Covid-19: From Benchtop to Bedside, ACS Biomaterials Science and Engineering (2021)
3. Nervous System Involvement in Covid-19: A Review of the Current Knowledge, Molecular Neurobiology (2021)
4. Covid-19 Pandemic: Insights Into Genetic Susceptibility to Sars-Cov-2 and Host Genes Implications on Virus Spread, Disease Severity and Outcomes, Human Antibodies (2022)
5. Current Status of Covid-19 Pandemic; Characteristics, Diagnosis, Prevention, and Treatment, Journal of Research in Medical Sciences (2020)
6. Corticosteroid Therapy for 2019 Novel Coronavirus: Lessons From Sars and Mers, Avicenna Journal of Clinical Microbiology and Infection (2021)
7. Gastrointestinal and Renal Complications in Sars-Cov-2-Infected Patients: Role of Immune System, Scandinavian Journal of Immunology (2021)
8. Cancer Care Management During the Covid-19 Pandemic, Risk Management and Healthcare Policy (2020)
Experts (# of related papers)
View all Related Experts
Shaghayegh Haghjooy Javanmard (8)
Shahrzad Ahangarzadeh (6)
Other Related Docs
9. Potential Inhibitors of Sars-Cov-2: Recent Advances, Journal of Drug Targeting (2021)
10. An Updated Review of the Association of Host Genetic Factors With Susceptibility and Resistance to Covid-19, Journal of Cellular Physiology (2021)
11. Epigenetic Regulation of Autophagy in Coronavirus Disease 2019 (Covid-19), Biochemistry and Biophysics Reports (2022)
12. Emerging Technologies for the Treatment of Covid-19, Advances in Experimental Medicine and Biology (2021)
13. Conceptual Framework for Sars-Cov-2-Related Lymphopenia, Advanced Biomedical Research (2022)
14. Cardiovascular Complications of Sars-Cov-2 Vaccines: An Overview, Cardiology and Therapy (2022)
15. Prevention of Covid-19: Preventive Strategies for General Population, Healthcare Setting, and Various Professions, Advances in Experimental Medicine and Biology (2021)
16. Comprehensive Overview of Covid-19-Related Respiratory Failure: Focus on Cellular Interactions, Cellular and Molecular Biology Letters (2022)
17. Mesenchymal Stem Cells: A Potent Cell Source for Covid-19, Coronaviruses (2021)
18. In Silico Investigation of Critical Binding Pattern in Sars-Cov-2 Spike Protein With Angiotensin-Converting Enzyme 2, Scientific Reports (2021)
19. A Review of Novel Coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2), Iranian Journal of Medical Microbiology (2020)
20. Aspects of Epidemiology, Pathology, Virology, Immunology, Transmission, Prevention, Prognosis, Diagnosis, and Treatment of Covid.19 Pandemic: A Narrative Review, International Journal of Preventive Medicine (2021)
21. Novel and Emerging Mutations of Sars-Cov-2: Biomedical Implications, Biomedicine and Pharmacotherapy (2021)
22. The Molecular Basis of Covid-19 Pathogenesis, Conventional and Nanomedicine Therapy, International Journal of Molecular Sciences (2021)
23. Study of the Possible Origin and Evolution of Coronaviruses, Focusing on Recent 2019 Novel Coronavirus (Covid-19), Journal of Isfahan Medical School (2021)
24. Potential Treatments for Covid-19; a Narrative Literature Review, Archives of Academic Emergency Medicine (2020)
25. An Overview on the Genomic Characteristics of the New Coronavirus (2019-Ncov) and the Prospective in Pathogenesis and Treatment of Covid-19 Infection, Journal of Isfahan Medical School (2020)
26. Classification of Viral Proteins Expressed by the Sars-Cov-2 Genome, Acta Microbiologica Hellenica (2022)
27. Reopening of Dental Clinics During Sars-Cov-2 Pandemic: An Evidence-Based Review of Literature for Clinical Interventions, Maxillofacial Plastic and Reconstructive Surgery (2020)
28. Recent Findings of Coronavirus: The Pathogenesis and Treatment, Journal of Isfahan Medical School (2020)
29. Herbal Medicines As Potential Inhibitors of Sars-Cov-2 Infection, Current Pharmaceutical Design (2022)
30. Using in Silico Bioinformatics Algorithms for the Accurate Prediction of the Impact of Spike Protein Mutations on the Pathogenicity, Stability, and Functionality of the Sars-Cov-2 Virus and Analysis of Potential Therapeutic Targets, Biochemical Genetics (2023)
31. Cancer Occurrence As the Upcoming Complications of Covid-19, Frontiers in Molecular Biosciences (2022)
32. Pi3k/Akt/Mtor Pathway: A Potential Target for Anti-Sars-Cov-2 Therapy, Immunologic Research (2022)
33. Controlling and Prevention of Novel Coronavirus Through Health and Safety Protocols in Food: Review Article, Tehran University Medical Journal (2021)
34. Novel Sars-Cov2 Poly Epitope Phage-Based Candidate Vaccine and Its Immunogenicity, Research in Pharmaceutical Sciences (2024)
35. Drug Repositioning Approach to Target Viral and Host Cells in Terms of Covid-19 Treatment: A Review of in Vivo Experiments and Clinical Studies, Journal of Experimental and Clinical Medicine (Turkey) (2022)
36. Nanosponges: An Overlooked Promising Strategy to Combat Sars-Cov-2, Drug Discovery Today (2022)
37. Vaccine Design and Delivery Approaches for Covid-19, International Immunopharmacology (2021)
38. Covid-19 Vaccines: Current and Future Challenges, Frontiers in Pharmacology (2024)
39. Acute Necrotizing Encephalopathy in Adult Patients With Covid-19: A Systematic Review of Case Reports and Case Series, Journal of Clinical Neurology (Korea) (2023)
40. A Review on the Diagnostic Approaches of Covid-19 Infection; Features and Limitations, Journal of Isfahan Medical School (2021)
41. Exploring the Out of Sight Antigens of Sars-Cov-2 to Design a Candidate Multi-Epitope Vaccine by Utilizing Immunoinformatics Approaches, Vaccine (2020)
42. A Mini-Review on Sofosbuvir and Daclatasvir Treatment in Coronavirus Disease 2019, New Microbes and New Infections (2021)
43. Sars-Cov-2 (Covid-19): New Discoveries and Current Challenges, Applied Sciences (Switzerland) (2020)
44. Time-Series Bioinformatics Analysis of Sars-Cov-Infected Cells to Identify the Biological Processes Associated With Severe Acute Respiratory Syndrome, Human Antibodies (2024)
45. An Overview on Role of Nutrition on Covid-19 Immunity: Accumulative Review From Available Studies, Clinical Nutrition Open Science (2023)
46. Interdisciplinary Approaches to Covid-19, Advances in Experimental Medicine and Biology (2021)
47. Genetics and Genomics of Sars-Cov-2: A Review of the Literature With the Special Focus on Genetic Diversity and Sars-Cov-2 Genome Detection, Genomics (2021)
48. Co-Infection Between the Severe Acute Respiratory Syndrome Coronavirus 2 and the Influenza Type B in Isfahan, Iran, Journal of Research in Medical Sciences (2021)
49. Chitin and Chitosan As Tools to Combat Covid-19: A Triple Approach, International Journal of Biological Macromolecules (2021)
50. Outlook of Therapeutic and Diagnostic Competency of Nanobodies Against Sars-Cov-2: A Systematic Review, Analytical Biochemistry (2022)