Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Relations Between Dietary Antioxidant Vitamins Intake and Oxidative Stress in Follicular Fluid and Art Outcomes



Kazemi A1 ; Ramezanzadeh F2 ; Nasresfahani MH3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Reproductive Health Department, Nursing and Midwifery Care Research Centere, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Vali-e-Asr Reproductive Health Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Reproductive Biomedicine Center, Royan Institute for Animal Biotechnology, ACECR, Department of Reproduction and Development, Isfahan, Iran

Source: Iranian Journal of Reproductive Medicine Published:2015

Abstract

Background: Oxidative stress (OS) in the follicular environment may affect on oocyte competence and antioxidant vitamins may modify its effects. Objective: This study was conducted to examine the effect of dietary intake of vitamin A, C and E on OS in follicular environment and assisted reproduction technology (ART) outcomes. Materials and Methods: In this obsevationalprospective study, the intake levels of vitamin A, C, and E were matured by validated food frequency questionnaire and Malondialdehyde and the total antioxidant capacity (TAC) levels of follicular fluid (FF) in 219 women undergoing ART were assessed. The number of retrieved oocytes, percentages of metaphase II MII) stage oocytes, fertilization rate, and embryo quality were also determined. Results: No significant association was found between vitamins intake levels and OS biomarkers, but the mean of TAC level in FF among women who received vitamin C greater than 75 mg/d was higher than women with lower intakes (p < 0.05). The ART parameters were not related to the vitamin E intake level, but the normal cleaved embryo rate was positively related to vitamin A (p < 0.05) and vitamin C (p=0.02) intake levels. Also, the percentage of MII oocytes (p=0.02) and the fertilization rate (p < 0.05) were related to the vitamin C intake level. The relation between the TAC level in FF and ART outcomes were not significant. Conclusion: Current results indicated that high dietary intake of vitamin C would be followed by increasing the TAC level in FF and improving the oocyte competence, but this effect of vitamin C is not dependent of increasing of antioxidant defense in follicular environment. © 2015 Research and Clinical Center for Infertitlity. All rights reserved.
Related Docs
View other Related Docs
1. Relationship Between Energy Expenditure Related Factors and Oxidative Stress in Follicular Fluid, International Journal of Fertility and Sterility (2014)
2. Impact of Environmental Tobacco Smoke Exposure in Women on Oxidative Stress in the Antral Follicle and Assisted Reproduction Outcomes, Journal of Research in Medical Sciences (2013)
3. Relationship Between Dietary Antioxidant Intake and Sperm Analysis Parameters, Iranian Journal of Obstetrics, Gynecology and Infertility (2018)
4. Omega-3 and Vitamin E Co-Supplementation Can Improve Antioxidant Markers in Obese/Overweight Women With Polycystic Ovary Syndrome, International Journal for Vitamin and Nutrition Research (2020)
5. Role of Dietary Antioxidants and Vitamins Intake in Semen Quality Parameters: A Cross-Sectional Study, Clinical Nutrition ESPEN (2022)
6. Relationship Between Dietary Fat Intake, Its Major Food Sources and Assisted Reproduction Parameters, Journal of Reproduction and Infertility (2014)
7. The Effect of Iron-Vitamin C Co-Supplementation on Biomarkers of Oxidative Stress in Iron-Deficient Female Youth, Biological Trace Element Research (2013)
8. The Effects of Serum and Follicular Fluid Vitamin D Levels on Assisted Reproductive Techniques: A Prospective Cohort Study, International Journal of Fertility and Sterility (2021)
Experts (# of related papers)
View all Related Experts
Reza Amani (5)
Mahboube Taebi (5)
Other Related Docs
9. Vitamin D Supplementation Affects Serum High-Sensitivity C-Reactive Protein, Insulin Resistance, and Biomarkers of Oxidative Stress in Pregnant Women, Journal of Nutrition (2013)
10. Dietary Patterns and the Outcomes of Assisted Reproductive Techniques in Women With Primary Infertility: A Prospective Cohort Study, International Journal of Fertility and Sterility (2019)
11. The Effects of Lycopene Supplement on the Spermatogram and Seminal Oxidative Stress in Infertile Men: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial, Phytotherapy Research (2019)
12. The Association Between Non-Enzymatic Dietary Total Antioxidant Capacity and Phytochemical Index With Semen Parameters: A Cross-Sectional Study in Isfahan Infertile Men, Journal of Nutrition and Food Security (2022)
13. The Association Between Dietary Antioxidants and Semen Parameters: A Cross-Sectional Study Among Iranian Infertile Men, Biological Trace Element Research (2022)
14. Effect of Vitamin D Supplementation on Intracytoplasmic Sperm Injection Outcomes: A Randomized Double-Blind Placebo-Controlled Trial, International Journal of Fertility and Sterility (2019)
15. The Association of Food Pattern and Sperm Quality Parameters and Biochemical Markers in Infertile Men: A Review Study, Journal of Health System Research (2020)
16. Dietary Fatty Acid Intakes and the Outcomes of Assisted Reproductive Technique in Infertile Women, Journal of Reproduction and Infertility (2021)
17. Vitamin D and Biomarkers of Inflammation and Oxidative Stress Among Pregnant Women: A Systematic Review of Observational Studies, BMC Immunology (2023)
18. The Association Between Vitamin C Dietary Intake and Its Serum Levels With Anthropometric Indices: A Systematic Review and Meta-Analysis, Complementary Therapies in Clinical Practice (2023)
19. The Effect of Antioxidant Vitamins E and C on Cognitive Performance of the Elderly With Mild Cognitive Impairment in Isfahan, Iran: A Double-Blind, Randomized, Placebo-Controlled Trial, European Journal of Nutrition (2014)
20. Effect of Cholesterol, Iron and Vitamin E on Protamine Deficiency and Dna Fragmentation of Male Rabbit Sperm, Journal of Isfahan Medical School (2014)
21. Vitamin D Supplementation for Premenstrual Syndrome-Related Inflammation and Antioxidant Markers in Students With Vitamin D Deficient: A Randomized Clinical Trial, Scientific Reports (2019)
22. The Association Between Serum Vitamin D Level and Sperm Parameters: A Pilot Study in a Subset of Iranian Infertile Males, Immunopathologia Persa (2020)
23. The Therapeutic Impact of Garlic (Allium Sativum) on Oxidative Stress Markers Among Polycystic Ovary Syndrome Patients: A Randomized, Double-Blinded Clinical Trial, International Journal of Preventive Medicine (2023)
24. The Effects of Zinc Methionine on Reproductive and Thyroid Hormones in Rats With Polycystic Ovarian Syndrome, Advanced Biomedical Research (2020)
25. The Effect of Multi Mineral‑Vitamin D Supplementation on Pregnancy Outcomes in Pregnant Women at Risk for Pre‑Eclampsia, International Journal of Preventive Medicine (2015)
26. Dietary Fats, Minerals and Semen Quality and Quantity Among Men Attending a Fertility Clinic: A Cross-Sectional Study in Iran, Journal of Nutrition and Food Security (2022)
27. Effect of a Plant-Based Diet on Oxidative Stress Biomarkers in Male Footballers, Scientific Reports (2024)
28. Evaluation of Correlation Between Antral Follicle Diameters With Follicular Output Rate (Fort) in Women Under Controlled Ovarian Hyperstimulation for Assisted Reproductive Techniques, Beni-Suef University Journal of Basic and Applied Sciences (2022)
29. The Effects of Chromium Supplementation on Endocrine Profiles, Biomarkers of Inflammation, and Oxidative Stress in Women With Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial, Biological Trace Element Research (2016)
30. Dietary Patterns Among Pregnant Women in the West-North of Iran, Pakistan Journal of Biological Sciences (2008)
31. Influence of Ω-3 Fatty Acid Eicosapentaenoic Acid on Igf-1 and Cox-2 Gene Expression in Granulosa Cells of Pcos Women, Iranian Journal of Reproductive Medicine (2015)
32. The Role of Micronutrients in Male and Female Fertility: A Review Study, Iranian Journal of Obstetrics, Gynecology and Infertility (2021)
33. Can Vitamin C Supplementation Reverse the Effects of Exercise Training in Polluted Air on Oxidative Stress Markers? a Randomized Controlled Trial, ARYA Atherosclerosis (2021)
34. Calcium Plus Vitamin D Supplementation Influences Biomarkers of Inflammation and Oxidative Stress in Overweight and Vitamin D-Deficient Women With Polycystic Ovary Syndrome: A Randomized Double-Blind Placebo-Controlled Clinical Trial, Clinical Endocrinology (2015)
35. Comparison of Oxidative Stress Indices in Pregnant Women With and Without Gestational Diabetes Mellitus, Journal of Isfahan Medical School (2019)
36. The Effect of Concentrated Pomegranate Juice on Biomarkers of Inflammation, Oxidative Stress, and Sex Hormones in Overweight and Obese Women With Polycystic Ovary Syndrome: A Randomized Controlled Trial, Phytotherapy Research (2023)
37. Dietary Total Antioxidant Capacity and Gestational Diabetes Mellitus: A Case-Control Study, Oxidative Medicine and Cellular Longevity (2020)
38. The Effect of Folic Acid and Nicotinic Acid on Malondialdehyde Levels of Semen in Oligospermia Men After Cryopreservation, Journal of Isfahan Medical School (2021)
39. The a Ssociation of 25-Hydroxy Vitamin D Level in Mothers With Term and Preterm Delivery and Their Neonates, Journal of Research in Medical Sciences (2020)
40. The Association Between Dietary Antioxidants, Oxidative Stress Markers, Abdominal Obesity and Poly-Cystic Ovary Syndrome: A Case Control Study, Journal of Obstetrics and Gynaecology (2020)
41. Antioxidant and Bone; Protect Your Future: A Brief Review, Iranian Journal of Public Health (2021)
42. Calcium-Vitamin D Co-Supplementation Affects Metabolic Profiles, But Not Pregnancy Outcomes, in Healthy Pregnant Women, International Journal of Preventive Medicine (2016)
43. Is There a Relationship Between Serum Vitamin D and Semen Parameters? a Cross-Sectional Sample of the Iranian Infertile Men, Basic and Clinical Andrology (2021)
44. Association of Anti-Mullerian Hormone on Oocyte Maturation, Fertilization, and Pregnancy Rates in Patients Under Assisted Reproductive Technology Cycles: A Cross-Sectional Study, International Journal of Fertility and Sterility (2024)
45. Multivitamin Versus Multivitamin-Mineral Supplementation and Pregnancy Outcomes: A Single-Blind Randomized Clinical Trial, International Journal of Preventive Medicine (2014)
46. Dietary Acid Load and Risk of Diminished Ovarian Reserve: A Case-Control Study, Reproductive Biology and Endocrinology (2024)
47. Determinants of Hypovitaminosis D in Pregnant Women and Their Newborns in a Sunny Region, International Journal of Endocrinology (2013)
48. Effects of Eicosapentaenoic Acid and Vitamin E on the Plasma Levels of Antioxidant Vitamins and Inflammatory Markers, and on Erythrocyte Antioxidant Enzyme Activities, in Male Basketball Players, Acta Medica Iranica (2009)
49. The Effect of Vitamin D on the Assisted Reproductive Techniques (Art) Outcomes: A Narrative Review, Iranian Journal of Obstetrics, Gynecology and Infertility (2024)
50. The Relationship Between Maternal Vitamin D Levels and Osteopenia Development in Preterm Infants: A Cross-Sectional Study, International Journal of Reproductive BioMedicine (2024)